MoleCode AGENTS.md

Repository instructions for MoleCode, an LLM-oriented way to represent molecules as typed Mermaid graphs. A molecule is a chemical structure; the format can convert to and from SMILES or MOL files using RDKit.

In plain words
What is it for?
Understanding and editing small molecules, polymers, and Markush structures, converting chemical formats, and using the repository’s MoleCode skill and command-line tools.
Why use it?
They tell coding agents to use the project’s explicit graph representation when understanding or editing molecules, making atoms and bonds easier to inspect and modify.

Instructions file for CodexOpenCode

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add instructions/atomflow-ai/molecode/agents-md
Clone the repo
git clone --depth 1 https://github.com/AtomFlow-AI/MoleCode

Made for: Codex, OpenCode.

Per session 847 This file is loaded in full into every session.
When invoked 847 The same file — it is already loaded in full.
Security scan A 0 findings. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5 $0.00847 $0.00847
Opus 5 $0.00424 $0.00424
Sonnet 5 $0.00169 $0.00169
Haiku 4.5 $0.00085 $0.00085

Measured yesterday against content hash c3ea17bbaa0b, method: parsed. Prices are Anthropic first-party input rates as of 2026-08-30, from the pricing page.

Security

Grade A, and why

MoleCode AGENTS.md scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured yesterday.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

AGENTS.md · 70 lines

How it starts

The opening of the file, as written. The whole thing — 70 lines — stays where its author put it; the contents beside it link to each section on GitHub.

AGENTS.md — MoleCode

Guidance for coding agents (Claude Code, Codex, and compatible tools) working in this repository.

What this repo is

MoleCode is an LLM-native molecular representation: it serializes a molecule as an explicit Mermaid graph where every atom and bond is a typed, named node/edge, losslessly inter-convertible with SMILES / MOL via RDKit. It covers three domains with one grammar — small molecules, polymers (PSMILES repeat units), and Markush structures ({} R-groups).

The installable library lives in molecode/; user-facing docs are in docs/; runnable examples in examples/.

Use the MoleCode skill

A ready-to-use Agent Skill ships in this repo at .claude/skills/molecode/:

MoleCode-first rule

For any molecule understanding or editing task, work at the explicit graph level: convert SMILES → MoleCode, inspect/edit the named nodes and edges, then validate and convert back. This is more reliable than reasoning over linear SMILES and safer than hand-writing a new SMILES for structural edits.

CLI quick start

# from the repo root (the script finds the molecode package automatically)
python .claude/skills/molecode/scripts/molecode_convert.py doctor
python .claude/skills/molecode/scripts/molecode_convert.py smiles-to-molecode "CCO" --name Ethanol
python .claude/skills/molecode/scripts/molecode_convert.py validate --input edited.mmd
python .claude/skills/molecode/scripts/molecode_convert.py molecode-to-smiles --input edited.mmd

Read the full file on GitHub · 70 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. yesterday First seen · 70 lines · 847 tokens per session scan A c3ea17bbaa0b

Subscribe to this mod's changes

MoleCode AGENTS.md is an instructions file published in the GitHub repository AtomFlow-AI/MoleCode (297 stars, last pushed 2mo ago), licensed MIT. It adds 847 tokens to every session, about $0.0042 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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