Agent
Expert in multiple testing procedures and multiplicity adjustment optimization. Handles Holm, Hochberg, Hommel, chain procedures, and gatekeeping strategies for Type I error control.
11 3mo ago A 38 tokens
original MIT
Agent
Power and sample size optimization using direct and tradeoff-based strategies. Performs qualitative and quantitative sensitivity assessments.
11 3mo ago A 24 tokens
original MIT
Agent
Entry point for clinical trial simulation requests. Routes to appropriate specialists based on trial design (TTE, CSE, multiplicity, group sequential). Use PROACTIVELY for routing.
11 3mo ago A 41 tokens
original MIT
Agent
Time-to-event simulation specialist using simtrial. Handles piecewise exponential survival, weighted logrank tests, MaxCombo, RMST, and milestone analyses. Use PROACTIVELY for survival/TTE simulations.
11 3mo ago A 45 tokens
original MIT
cse-analysis
29Command
Full Clinical Scenario Evaluation workflow using Mediana framework.
11 3mo ago A 14 tokens
original MIT
gs-design
30Command
Design group sequential trials with interim analyses, alpha spending, and futility stopping.
11 3mo ago A 19 tokens
original MIT
Command
Optimize multiplicity adjustment selection including procedure choice and parameter tuning.
11 3mo ago A 17 tokens
original MIT
Command
Calculate power for various clinical trial designs using simtrial or Mediana frameworks.
11 3mo ago A 18 tokens
original MIT
sample-size
33Command
Determine sample sizes given power requirements using simulation-based optimization.
11 3mo ago A 14 tokens
original MIT
Skill Claude CodeCodex
Common clinical trial design patterns including multi-arm, multi-endpoint, adaptive, and stratified designs. Use when selecting or implementing trial designs.
11 3mo ago A 35 tokens
original MIT
Skill Claude CodeCodex
Group sequential design methods for interim analyses, alpha spending, and futility stopping. Use when designing trials with interim looks or implementing spending functions.
11 3mo ago A 34 tokens
original MIT
Skill Claude CodeCodex
Core Mediana package functions for Clinical Scenario Evaluation (CSE). Use when designing data models, analysis models, evaluation models, and running comprehensive trial simulations.
11 3mo ago A 38 tokens
original MIT
Skill Claude CodeCodex
Multiple testing procedures reference for clinical trials. Use when selecting or implementing multiplicity adjustments, gatekeeping procedures, or graphical approaches.
11 3mo ago A 30 tokens
original MIT
Skill Claude CodeCodex
Direct and tradeoff-based optimization strategies for clinical trial design. Use when optimizing sample size, selecting design parameters, or performing sensitivity analysis.
11 3mo ago A 33 tokens
original MIT
Skill Claude CodeCodex
Core simtrial package functions for time-to-event clinical trial simulation. Use when generating survival data, performing weighted logrank tests, or running TTE simulations.
11 3mo ago A 38 tokens
original MIT
Skill Claude CodeCodex
Survival analysis methods including weighted logrank, MaxCombo, RMST, and milestone tests. Use when analyzing TTE data or choosing analysis methods for non-proportional hazards.
11 3mo ago A 42 tokens
original MIT
itc-modeling
41Plugin Claude Code
Expert agents for indirect treatment comparison modeling in R.
11 3mo ago A
tokens not measured
original MIT
Agent
Master ITC strategist specializing in evidence synthesis methodology, study design assessment, and indirect treatment comparison method selection. Helps choose between pairwise MA, NMA, MAIC, STC, and ML-NMR based on data availability and assumptions. Use PROACTIVELY when planning ITC analyses or needing guidance on…
11 3mo ago A 70 tokens
original MIT
Agent
Expert ITC R code reviewer who identifies methodological errors, statistical issues, and code quality problems. Offers comprehensive or summary reviews, and can amend code (saved to subfolder to prevent data loss). Use PROACTIVELY when reviewing ITC analysis code.
11 3mo ago A 57 tokens
original MIT
Agent
Expert in Matching-Adjusted Indirect Comparison using the maicplus package. Handles weight estimation, anchored/unanchored MAIC, binary/continuous/TTE endpoints, ESS diagnostics, and Bucher comparisons. Use PROACTIVELY for MAIC analyses.
11 3mo ago A 56 tokens
original MIT
Agent
Expert in Multilevel Network Meta-Regression using the multinma package. Handles combined IPD/AgD networks, population adjustment, covariate integration, and prediction to target populations. Use PROACTIVELY for ML-NMR analyses.
11 3mo ago A 54 tokens
original MIT
Agent
Expert in frequentist and Bayesian network meta-analysis using netmeta and gemtc packages. Handles network visualization, consistency assessment, treatment rankings, and league tables. Use PROACTIVELY for NMA tasks involving multiple treatment comparisons.
11 3mo ago A 50 tokens
original MIT
Agent
Expert in frequentist and Bayesian pairwise meta-analysis using meta, metafor, and bayesmeta packages. Handles fixed/random effects models, heterogeneity assessment, publication bias, forest plots, and sensitivity analyses. Use PROACTIVELY for pairwise MA tasks.
11 3mo ago A 60 tokens
original MIT
Agent
Expert in Simulated Treatment Comparison using transparent outcome-regression methods. Handles anchored and unanchored STC for binary, continuous, count, and survival outcomes with explicit assumptions and sensitivity analyses. Use PROACTIVELY for STC analyses.
11 3mo ago A 53 tokens
original MIT