ml-nmr-specialist

ml-nmr-specialist is an agent for Claude Code from choxos/BiostatAgent. It costs 54 tokens per session (2,204 once invoked), scanned A, original, MIT.

An expert agent for multilevel network meta-regression (ML-NMR), which combines evidence from studies with individual patient data and studies with summary data. It adjusts for population differences and can predict treatment effects for a defined target population.

In plain words
What is it for?
Use it for ML-NMR analyses with mixed data types, covariate integration, treatment-effect heterogeneity, Bayesian modelling, disconnected networks, and marginal or conditional effect estimates.
Why use it?
It helps apply complex population-adjusted evidence synthesis while accounting for uncertainty from the data and model. It also supports situations where standard network meta-analysis may not properly handle differing populations.

Agent for Claude Code

Written for Claude Code: shipped in a Claude Code plugin. Also seen: model in frontmatter.

Part of the itc-modeling plugin — 6 skills, 2 commands, 7 agents shipped together

Good fit Use it for ML-NMR analyses with mixed data types, covariate integration, treatment-effect heterogeneity, Bayesian modelling, disconnected networks, and marginal or conditional effect estimates.

Compare 6 agents from other repositories ↓
Install with agentmods
npx agentmods add agents/choxos/biostatagent/ml-nmr-specialist
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Clone the repo
git clone --depth 1 https://github.com/choxos/BiostatAgent

Made for: Claude Code.

Or install itc-modeling, the plugin that ships this one along with the rest of its 6 skills, 2 commands, 7 agents.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for ml-nmr-specialist

README.md
[![agentmods](https://agentmods.dev/badge/agents/choxos/biostatagent/ml-nmr-specialist/github.svg)](https://agentmods.dev/agents/choxos/biostatagent/ml-nmr-specialist)
Your own site
<a href="https://agentmods.dev/agents/choxos/biostatagent/ml-nmr-specialist"><img src="https://agentmods.dev/badge/agents/choxos/biostatagent/ml-nmr-specialist/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for ml-nmr-specialist

Your own site · 80×15
<a href="https://agentmods.dev/agents/choxos/biostatagent/ml-nmr-specialist"><img src="https://agentmods.dev/badge/agents/choxos/biostatagent/ml-nmr-specialist.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 54 Only the description is in the session, so the agent can decide to use it. The body loads when it is invoked.
When invoked 2,204 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00054 $0.02204
Opus 5 $0.00027 $0.01102
Sonnet 5 $0.00011 $0.00441
Haiku 4.5 $0.00005 $0.00220

Measured 11d ago against content hash ebca58dd1855, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

ml-nmr-specialist scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 11d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

plugins/itc-modeling/agents/ml-nmr-specialist.md · 315 lines

How it starts

The opening of the file, as written. The whole thing — 315 lines — stays where its author put it; the contents beside it link to each section on GitHub.

You are an expert biostatistician specializing in Multilevel Network Meta-Regression (ML-NMR), with deep expertise in the multinma package for population-adjusted evidence synthesis across networks.

Purpose

Expert ML-NMR specialist who synthesizes evidence across networks combining individual patient data (IPD) and aggregate data (AgD) with population adjustment. Masters Bayesian methodology with Stan backend, enabling prediction to specific target populations and proper uncertainty propagation following NICE DSU TSD 18 guidance.

Capabilities

Core ML-NMR Methodology

When to Use
  • Network of treatments with mixture of IPD and AgD
  • Population differences across trials
  • Want to leverage all available data (not just IPD trials)
  • Need prediction to specific target population
  • Treatment effect heterogeneity across populations
Key Features
  • Borrows strength across entire network
  • Proper uncertainty propagation from all sources
  • Prediction to any target population with known covariates
  • Handles disconnected networks (with stronger assumptions)
  • Marginal and conditional effect estimation

Network Data Setup

IPD Studies
  • set_ipd() - Individual patient-level data
  • Covariates at patient level
  • Outcomes per patient
AgD Studies (Arm-Level)
  • set_agd_arm() - Arm-level aggregate data
  • Event counts and sample sizes
  • Covariate summaries per arm
AgD Studies (Contrast-Level)
  • set_agd_contrast() - Contrast-level data
  • Treatment effects and standard errors
  • Correlation for multi-arm trials
Network Combination
  • combine_network() - Merge IPD and AgD
  • Consistent treatment coding
  • Covariate harmonization

Population Adjustment

Integration Points
  • add_integration() - Numerical integration for AgD
  • Quasi-Monte Carlo integration
  • Gaussian quadrature
  • Number of integration points selection
Covariate Handling
  • Effect modifier specification
  • Prognostic factor adjustment
  • Continuous and categorical covariates
  • Interaction specification

Read the full file on GitHub · 315 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 11d ago First seen · 315 lines · 54 tokens per session scan A ebca58dd1855

Subscribe to this mod's changes

ml-nmr-specialist is an agent published in the GitHub repository choxos/BiostatAgent (11 stars, last pushed 3mo ago), licensed MIT. It adds 54 tokens to every session and 2,204 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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