cryocore: Instructions file for Codex

AGENTS.md

cryocore AGENTS.md is an instructions file for Codex, OpenCode from BioSymphony/cryocore. It costs 945 tokens per session, scanned A, original, MIT.

Repository instructions for BioSymphony CryoCore, a software control plane for producing and checking evidence from cryo-electron microscopy, a method for studying biological structures.

In plain words
What is it for?
Use them when developing CryoCore, validating microscopy maps or models, reviewing structural variation, rendering structures, or recording project-specific lessons.
Why use it?
They help an agent keep documentation, campaign files, scripts, examples, tool records, and private research data in the right places while following project boundaries.

Instructions file for CodexOpenCode

Written for Codex and OpenCode: the file is AGENTS.md.

This is BioSymphony/cryocore's own configuration. It tells Codex and OpenCode how to work on cryocore itself, so it is not a mod to install elsewhere. Copy it as a starting point and replace the rules that are about this project. Everything cryocore configures →

Reuse

Borrowing it

Nothing to install: this file belongs to BioSymphony/cryocore. Take a copy, put it at the same path in your own repository, and replace the rules that are about this project with yours.

Copy the file
curl -O https://raw.githubusercontent.com/BioSymphony/cryocore/main/AGENTS.md
Clone the repo
git clone --depth 1 https://github.com/BioSymphony/cryocore

Made for: Codex, OpenCode.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

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README.md
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Per session 945 This file is loaded in full into every session.
When invoked 945 The same file — it is already loaded in full.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00945 $0.00945
Opus 5.5 $0.00378 $0.00378
Sonnet 5.5 $0.00189 $0.00189
Haiku 4.5 $0.00094 $0.00094

Measured 2mo ago against content hash 6e103b3921ab, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

cryocore AGENTS.md scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2mo ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

AGENTS.md · 75 lines

How it starts

The opening of the file, as written. The whole thing — 75 lines — stays where its author put it; the contents beside it link to each section on GitHub.

BioSymphony CryoCore Agent Guide

This repo is the public BioSymphony CryoCore control plane. It owns cryo-EM evidence production, map/model validation, heterogeneity review, and structural rendering lanes that should not be coupled to AI design runtimes.

Operating Rules

  • Keep durable design docs in docs/.
  • Keep campaign specs in campaigns/<campaign-id>/.
  • Keep public-safe example manifests and tiny fixtures in examples/.
  • Keep reusable module contracts in modules/.
  • Keep tool and licensing posture in references/software-registry.yaml and docs/tooling-and-licensing.md.
  • Keep reusable scripts under scripts/cryocore/.
  • Use templates/linear-issue.md when drafting tracker-neutral external-agent issues.
  • Record durable learnings (tool surprises, failed paths, provider gotchas, doctrine corrections) in .cryocore-memory/ in this checkout (gitignored, never committed) or in your harness's own memory store. See Agent Memory And Learnings for scope, exclusions, harness pointers, and the note shape at skills/cryocore/references/memory-note-template.md.
  • Do not store API keys, tokens, raw cryo-EM movies, maps, half-maps, private structures, unpublished sequences, model weights, license files, or heavy outputs in this repo.
  • Store heavy outputs under ignored directories such as .runtime/, artifacts/, outputs/, provider volumes, or secure local storage.
  • Treat ChimeraX as intentionally duplicated with Structure Factory: runtime-gated, noncommercial/commercial-license posture recorded per campaign, and never redistributed in this public repo.

Ownership Boundary

CryoCore owns:

  • raw cryo-EM movie intake contracts
  • motion correction, CTF, picking, classification, refinement, and map postprocessing plans
  • map/model validation and atomic model build lanes
  • heterogeneity and conformational-state evidence lanes
  • ChimeraX/Coot/PyMOL/Blender/Mol* figure and review scaffolding
  • provider-neutral cryo-EM execution contracts for local, RunPod, AWS Batch, SSH/HPC, and neocloud-style backends

Read the full file on GitHub · 75 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2mo ago First seen · 75 lines · 945 tokens per session scan A 6e103b3921ab

Subscribe to this mod's changes

cryocore AGENTS.md is an instructions file published in the GitHub repository BioSymphony/cryocore (6 stars, last pushed 12d ago), licensed MIT. It adds 945 tokens to every session, about $0.0038 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

Related

cryocore AGENTS.md compared with instructions from other repositories

cryocore AGENTS.md next to 6 instructions from other repositories
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cryocore AGENTS.mdBioSymphony/cryocoreInstructions file612d agoMITA945Codex, OpenCode
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