Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.
xuzhougeng/wisp-science is a local-first desktop workbench for scientific research that combines AI assistants with Python and R computing, literature search, scientific databases, and remote runtimes. Researchers use it to run analyses, manage project artifacts, and preserve evidence and decisions on their own machines. Its catalogue skills and instruction extend the workbench’s reusable agent workflows.
Latest release v1.21.0 — v1.21.0: Context Reuse · 上下文复用 · 24 Oct 2026
1 file for Codex and OpenCode: wisp-science AGENTS.md — 2,988 tokens loaded in every session.
AGENTS.md A 2,988 tok These files are xuzhougeng/wisp-science's own configuration — they tell Codex and OpenCode how to work on this repository, so they are not mods to install elsewhere. Copy one as a starting point and replace the parts that are about this project.