BioTender-max/awesome-bio-agent-skills

A curated collection of AI agent skills for biomedical research, covering genomics, proteomics, single-cell analysis, clinical AI, and protein design.

178Stars on the repository
200Mods indexed here, across every type
2mo agoLast push, which is what freshness is scored on
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small-rna-seq

99

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Workflow for small RNA and miRNA preprocessing, quantification, differential analysis, and target-oriented interpretation.

not rated 178 +6 2mo ago A 26 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

SPR and BLI assay planning, kinetic interpretation, and troubleshooting guidance. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.

not rated 178 +6 2mo ago A 63 tokens

systems-biology

102

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Workflow for constraint-based metabolic modeling, context-specific models, gene essentiality, and systems-level interpretation.

not rated 178 +6 2mo ago A 24 tokens

variant-calling

104

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Workflow for small-variant and structural-variant discovery, filtering, annotation, and interpretation from sequencing data.

not rated 178 +6 2mo ago A 25 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Species abundance estimation using Bracken with Kraken2 output. Redistributes reads from higher taxonomic levels to species for more accurate estimates. Use when accurate species-level abundances are needed from Kraken2 classification output.

not rated 178 +6 2mo ago A 48 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017…

not rated 178 +6 2mo ago A 161 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequences. Use when FastQC shows adapter contamination or before alignment of short reads.

not rated 178 +6 2mo ago A 60 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive…

not rated 178 +6 2mo ago A 147 tokens

bio-admet-prediction

110

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness…

not rated 178 +6 2mo ago A 115 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA…

not rated 178 +6 2mo ago A 152 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.

not rated 178 +6 2mo ago A 71 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Filter alignments by flags, mapping quality, and regions using samtools view and pysam. Use when extracting specific reads, removing low-quality alignments, or subsetting to target regions.

not rated 178 +6 2mo ago A 44 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Create and use BAI/CSI indices for BAM/CRAM files using samtools and pysam. Use when enabling random access to alignment files or fetching specific genomic regions.

not rated 178 +6 2mo ago A 41 tokens

bio-alignment-io

116

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.

not rated 178 +6 2mo ago A 64 tokens

bio-alignment-sorting

117

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.

not rated 178 +6 2mo ago A 37 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Trim multiple sequence alignments using ClipKIT, trimAl, BMGE, Divvier, or HMMcleaner with mode selection guidance per downstream goal. Use when removing unreliable columns or contaminating residues before phylogenetic inference, HMM building, or selection analysis.

not rated 178 +6 2mo ago A 60 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics. Use when verifying alignment data quality before variant calling or quantification.

not rated 178 +6 2mo ago A 43 tokens

BioTender-max/awesome-bio-agent-skills

Skill Claude CodeCodex

Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or…

not rated 178 +6 2mo ago A 93 tokens

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