reactome-database

reactome-database is a skill for Claude Code, Codex from google-deepmind/science-skills. It costs 73 tokens per session (2,801 once invoked), scanned A, original, Apache-2.0.

A connector for Reactome, a curated database of biological pathways—sets of reactions and processes in living systems. It supports pathway analysis, identifier mapping, reaction details, hierarchy browsing, diagram export, and related searches.

In plain words
What is it for?
Use it to analyse gene or protein lists, find enriched pathways, map identifiers, inspect reaction inputs and outputs, browse pathway relationships, and export pathway diagrams.
Why use it?
It avoids switching between separate Reactome services for gene-list analysis and pathway research. It can also show which identifiers were not found or could not be mapped.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to analyse gene or protein lists, find enriched pathways, map identifiers, inspect reaction inputs and outputs, browse pathway relationships, and export pathway diagrams.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/google-deepmind/science-skills/reactome_database
About the project

Science Skills is a collection of add-ons that give AI agents structured instructions, scripts, and references for scientific research, including genomics, structural biology, cheminformatics, and literature search. Researchers use it to guide agents through specialized scientific tasks with information from databases and tools such as AlphaGenome, AFDB, and UniProt. The catalogue entries are individual skills from this collection.

google-deepmind/science-skills · 3,307 stars · on GitHub · antigravity.google

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add google-deepmind/science-skills --skill reactome_database
Clone the repo
git clone --depth 1 https://github.com/google-deepmind/science-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for reactome-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/google-deepmind/science-skills/reactome_database/github.svg)](https://agentmods.dev/skills/google-deepmind/science-skills/reactome_database)
Your own site
<a href="https://agentmods.dev/skills/google-deepmind/science-skills/reactome_database"><img src="https://agentmods.dev/badge/skills/google-deepmind/science-skills/reactome_database/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for reactome-database

Your own site · 80×15
<a href="https://agentmods.dev/skills/google-deepmind/science-skills/reactome_database"><img src="https://agentmods.dev/badge/skills/google-deepmind/science-skills/reactome_database.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 73 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,801 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00073 $0.02801
Opus 5.5 $0.00029 $0.01120
Sonnet 5.5 $0.00015 $0.00560
Haiku 4.5 $0.00007 $0.00280

Measured 1mo ago against content hash bccfb05ac68a, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

reactome-database scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 1mo ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/reactome_analysis.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/reactome_database/SKILL.md · 282 lines

How it starts

The opening of the file, as written. The whole thing — 282 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Reactome Analysis & Content Service

Prerequisites

  1. uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
  2. User Notification: If .licenses/reactome_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://reactome.org/license and https://reactome.org/cite, then (2) create the file recording the notification text and timestamp.

Overview

Reactome is a free, open-source, curated pathway database. This skill wraps both the Analysis Service (https://reactome.org/AnalysisService/) and the Content Service (https://reactome.org/ContentService/) providing pathway enrichment analysis, identifier mapping, reaction details, pathway hierarchy navigation, diagram export, cross-reference mapping, and search.

When to Use This Skill

  • Performing pathway enrichment (overrepresentation) analysis on gene/protein lists
  • Retrieving analysis results using a token from previous enrichment
  • Identifying which genes or proteins were not found in a pathway analysis
  • Analyzing gene expression data against pathway annotations
  • Mapping identifiers to Reactome entities across species
  • Retrieving reaction participants (inputs, outputs, catalysts, regulators)
  • Navigating pathway hierarchy and listing top-level pathways
  • Finding which complexes or sets contain a protein
  • Exporting pathway/reaction diagrams (PNG/SVG) with gene highlighting
  • Cross-referencing identifiers across databases (UniProt, Ensembl, etc.)
  • Searching the Reactome knowledgebase
  • Downloading analysis reports (PDF, CSV, JSON)
  • Comparing pathways across species

Common Species IDs

Reference list for common research organisms:

  • Homo sapiens
    • ID: 9606
  • Mus musculus (Mouse)
    • ID: 48892
  • Rattus norvegicus (Rat)
    • ID: 48895

Common Pathway IDs

Reference list for commonly used Reactome pathway stable IDs:

Read the full file on GitHub · 282 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 1mo ago First seen · 282 lines · 73 tokens per session scan A bccfb05ac68a

Subscribe to this mod's changes

reactome-database is a skill published in the GitHub repository google-deepmind/science-skills (3,307 stars, last pushed 6d ago), licensed Apache-2.0. It adds 73 tokens to every session and 2,801 once invoked, about $0.0003 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

Other skills, from other repositories

torchdrug

Builds and troubleshoots TorchDrug 0.2.1 workflows for molecular graphs, property prediction, self-supervised pretraining, molecule generation, retrosynthesis, protein representation learning, and knowledge graph reasoning. Use when code imports torchdrug or needs its datasets, models, tasks, or Engine.

K-Dense-AI/scientific-agent-skills · 64 tokens

arboreto

Infers candidate gene regulatory networks from bulk or single-cell expression data using AertsLab Arboreto GRNBoost2 and GENIE3. Use for transcription factor-target association ranking, compatible Dask execution, sparse expression inputs, and network stability checks.

K-Dense-AI/scientific-agent-skills · 55 tokens

deepspot-m

Generates transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Used for predicted log1p-CPM expression from 224x224 tiles at about 20x, querying the released protein-coding gene panel by symbol, and whole-slide prediction after resolution-aware tiling with histolab.

K-Dense-AI/scientific-agent-skills · 70 tokens

pyhealth

Builds and validates PyHealth clinical machine-learning pipelines for EHR, signals, imaging, and medical codes. Use for PyHealth dataset loading, MIMIC-III/IV, eICU or OMOP prediction tasks, patient-level evaluation, mortality/readmission/length-of-stay modeling, medication recommendation, sleep staging, Trainer…

K-Dense-AI/scientific-agent-skills · 84 tokens

ml-training-recipes

Battle-tested PyTorch training recipes for all domains — LLMs, vision, diffusion, medical imaging, protein/drug discovery, spatial omics, genomics. Covers training loops, optimizer selection (AdamW, Muon), LR scheduling, mixed precision, debugging, and systematic experimentation. Use when training or fine-tuning…

Orchestra-Research/AI-Research-SKILLs · 88 tokens

nemo-mbridge-perf-expert-parallel-overlap

Validate and use MoE expert-parallel communication overlap in Megatron-Bridge, including overlapmoeexpertparallelcomm, delaywgradcompute, and flex dispatcher backends such as DeepEP and HybridEP.

NVIDIA/skills · 56 tokens