synthetic-sciences/openscience

synthetic-sciences/openscience

Skill Claude CodeCodex

Framework for state-of-the-art sentence, text, and image embeddings. Provides 5000+ pre-trained models for semantic similarity, clustering, and retrieval. Supports multilingual, domain-specific, and multimodal models. Use for generating embeddings for RAG, semantic search, or similarity tasks. Best for production…

synthetic-sciences/openscience

Skill Claude CodeCodex

Language-independent tokenizer treating text as raw Unicode. Supports BPE and Unigram algorithms. Fast (50k sentences/sec), lightweight (6MB memory), deterministic vocabulary. Used by T5, ALBERT, XLNet, mBART. Train on raw text without pre-tokenization. Use when you need multilingual support, CJK languages, or…

synthetic-sciences/openscience

Skill Claude CodeCodex

State-of-the-art text-to-image generation with Stable Diffusion models via HuggingFace Diffusers. Use when generating images from text prompts, performing image-to-image translation, inpainting, or building custom diffusion pipelines.

synthetic-sciences/openscience

Skill Claude CodeCodex

This skill should be used when working with pre-trained transformer models for natural language processing, computer vision, audio, or multimodal tasks. Use for text generation, classification, question answering, translation, summarization, image classification, object detection, speech recognition, and fine-tuning…

synthetic-sciences/openscience

Skill Claude CodeCodex

OpenAI's general-purpose speech recognition model. Supports 99 languages, transcription, translation to English, and language identification. Six model sizes from tiny (39M params) to large (1550M params). Use for speech-to-text, podcast transcription, or multilingual audio processing. Best for robust, multilingual…

synthetic-sciences/openscience

Skill Claude CodeCodex

GGUF format and llama.cpp quantization for efficient CPU/GPU inference. Use when deploying models on consumer hardware, Apple Silicon, or when needing flexible quantization from 2-8 bit without GPU requirements.

synthetic-sciences/openscience

Skill Claude CodeCodex

Ultra-fast LLM inference on custom LPU hardware. OpenAI-compatible API at api.groq.com. Lowest latency in the industry (500-1000+ tok/s). Supports chat completions, vision, audio (Whisper STT + TTS), tool calling, JSON mode, and streaming. Free tier available. Inference only — no training.

synthetic-sciences/openscience

Skill Claude CodeCodex

Runs LLM inference on CPU, Apple Silicon, and consumer GPUs without NVIDIA hardware. Use for edge deployment, M1/M2/M3 Macs, AMD/Intel GPUs, or when CUDA is unavailable. Supports GGUF quantization (1.5-8 bit) for reduced memory and 4-10× speedup vs PyTorch on CPU.

synthetic-sciences/openscience

Skill Claude CodeCodex

Provides guidance for enterprise-grade RL training using miles, a production-ready fork of slime. Use when training large MoE models with FP8/INT4, needing train-inference alignment, or requiring speculative RL for maximum throughput.

synthetic-sciences/openscience

Skill Claude CodeCodex

Open-source AI observability platform for LLM tracing, evaluation, and monitoring. Use when debugging LLM applications with detailed traces, running evaluations on datasets, or monitoring production AI systems with real-time insights.

synthetic-sciences/openscience

Skill Claude CodeCodex

Fast structured generation and serving for LLMs with RadixAttention prefix caching. Use for JSON/regex outputs, constrained decoding, agentic workflows with tool calls, or when you need 5× faster inference than vLLM with prefix sharing. Powers 300,000+ GPUs at xAI, AMD, NVIDIA, and LinkedIn.

synthetic-sciences/openscience

Skill Claude CodeCodex

Accelerate LLM inference using speculative decoding, Medusa multiple heads, and lookahead decoding techniques. Use when optimizing inference speed (1.5-3.6× speedup), reducing latency for real-time applications, or deploying models with limited compute. Covers draft models, tree-based attention, Jacobi iteration…

synthetic-sciences/openscience

Skill Claude CodeCodex

Optimizes LLM inference with NVIDIA TensorRT for maximum throughput and lowest latency. Use for production deployment on NVIDIA GPUs (A100/H100), when you need 10-100x faster inference than PyTorch, or for serving models with quantization (FP8/INT4), in-flight batching, and multi-GPU scaling.

synthetic-sciences/openscience

Skill Claude CodeCodex

Serves LLMs with high throughput using vLLM's PagedAttention and continuous batching. Use when deploying production LLM APIs, optimizing inference latency/throughput, or serving models with limited GPU memory. Supports OpenAI-compatible endpoints, quantization (GPTQ/AWQ/FP8), and tensor parallelism.

synthetic-sciences/openscience

Skill Claude CodeCodex

Simplest distributed training API. 4 lines to add distributed support to any PyTorch script. Unified API for DeepSpeed/FSDP/Megatron/DDP. Automatic device placement, mixed precision (FP16/BF16/FP8). Interactive config, single launch command. HuggingFace ecosystem standard.

synthetic-sciences/openscience

Skill Claude CodeCodex

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API…

synthetic-sciences/openscience

Skill Claude CodeCodex

Activation-aware weight quantization for 4-bit LLM compression with 3x speedup and minimal accuracy loss. Use when deploying large models (7B-70B) on limited GPU memory, when you need faster inference than GPTQ with better accuracy preservation, or for instruction-tuned and multimodal models. MLSys 2024 Best Paper…

synthetic-sciences/openscience

Skill Claude CodeCodex needs its repo

Expert guidance for fine-tuning LLMs with Axolotl - YAML configs, 100+ models, LoRA/QLoRA, DPO/KTO/ORPO/GRPO, multimodal support.

synthetic-sciences/openscience

Skill Claude CodeCodex

Evaluates code generation models across HumanEval, MBPP, MultiPL-E, and 15+ benchmarks with pass@k metrics. Use when benchmarking code models, comparing coding abilities, testing multi-language support, or measuring code generation quality. Industry standard from BigCode Project used by HuggingFace leaderboards.

synthetic-sciences/openscience

Skill Claude CodeCodex

Quantizes LLMs to 8-bit or 4-bit for 50-75% memory reduction with minimal accuracy loss. Use when GPU memory is limited, need to fit larger models, or want faster inference. Supports INT8, NF4, FP4 formats, QLoRA training, and 8-bit optimizers. Works with HuggingFace Transformers.

synthetic-sciences/openscience

Skill Claude CodeCodex

Fine-tune LLMs on Google Colab GPUs directly from openscience. Connects to Colab runtimes via WebSocket bridge for remote training with Unsloth. Supports SFT, GRPO, DPO, vision, and TTS workflows on free T4 to Pro A100 GPUs.

synthetic-sciences/openscience

Skill Claude CodeCodex

Expert guidance for distributed training with DeepSpeed - ZeRO optimization stages, pipeline parallelism, FP16/BF16/FP8, 1-bit Adam, sparse attention.

synthetic-sciences/openscience

Skill Claude CodeCodex

Optimizes transformer attention with Flash Attention for 2-4x speedup and 10-20x memory reduction. Use when training/running transformers with long sequences (>512 tokens), encountering GPU memory issues with attention, or need faster inference. Supports PyTorch native SDPA, flash-attn library, H100 FP8, and sliding…

synthetic-sciences/openscience

Skill Claude CodeCodex

This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file…