bio-sra-data

bio-sra-data is a skill for Claude Code, Codex from thesecondfox/skill. It costs 44 tokens per session (2,662 once invoked), scanned D, original, MIT.

A guide to downloading raw DNA or RNA sequencing files from the NCBI Sequence Read Archive, a public database of sequencing experiments. It uses SRA accession codes to retrieve data as FASTQ files, which contain sequencing reads.

In plain words
What is it for?
Use it to download FASTQ files with the SRA Toolkit, prefetch large datasets, extract reads from accessions, and validate SRA downloads.
Why use it?
It gives a repeatable way to fetch large sequencing datasets and check that downloads completed correctly. It also points to tools for retrieving study metadata.

Skill for Claude CodeCodex

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/thesecondfox/skill/bio-database-access-sra-data
Any agent
npx skills add thesecondfox/skill --skill bio-database-access-sra-data
Clone the repo
git clone --depth 1 https://github.com/thesecondfox/skill

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-sra-data

README.md
[![agentmods](https://agentmods.dev/badge/skills/thesecondfox/skill/bio-database-access-sra-data.svg)](https://agentmods.dev/skills/thesecondfox/skill/bio-database-access-sra-data)
Your own site
<a href="https://agentmods.dev/skills/thesecondfox/skill/bio-database-access-sra-data"><img src="https://agentmods.dev/badge/skills/thesecondfox/skill/bio-database-access-sra-data.svg" alt="Measured on agentmods" height="20"></a>
Per session 44 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,662 The whole file, excluding the scripts and references it only reads on demand.
Security scan D 3 findings. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5 $0.00044 $0.02662
Opus 5 $0.00022 $0.01331
Sonnet 5 $0.00009 $0.00532
Haiku 4.5 $0.00004 $0.00266

Measured 3d ago against content hash 64eaa2379631, method: parsed. Prices are Anthropic first-party input rates as of 2026-08-30, from the pricing page.

Security

Grade D, and why

bio-sra-data scanned grade D with 3 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 3d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Asks for rootmediumPrivilege escalation

A mod that escalates privileges can change anything on the machine, not only the project.

sudo apt install sra-toolkit

Recursive force deletehighDestructive command

rm -rf with a variable or a broad path is one typo away from removing the wrong tree.

rm -rf ${OUTDIR}/${SRR}

Runs shell commandslowCapability

Expected in a hook, worth knowing in a rule or an instructions file.

- Python: `subprocess.run(['fasterq-dump', accession])` or `Entrez.efetch()` for metadata
Common_Skills/bio-database-access-sra-data/SKILL.md · 367 lines

How it starts

The opening of the file, as written. The whole thing — 367 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Version Compatibility

Reference examples tested with: BioPython 1.83+, Entrez Direct 21.0+, SRA Toolkit 3.0+

Before using code patterns, verify installed versions match. If versions differ:

  • Python: pip show <package> then help(module.function) to check signatures
  • CLI: <tool> --version then <tool> --help to confirm flags

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

SRA Data

Download raw sequencing data from the Sequence Read Archive using the SRA toolkit.

"Download FASTQ from SRA" → Fetch raw sequencing reads from an SRA accession as FASTQ files.

  • CLI: fasterq-dump SRR_ACCESSION (SRA Toolkit)
  • Python: subprocess.run(['fasterq-dump', accession]) or Entrez.efetch() for metadata

Installation

# macOS
brew install sratoolkit

# Ubuntu/Debian
sudo apt install sra-toolkit

# conda (recommended)
conda install -c bioconda sra-tools

# Verify installation
fasterq-dump --version

Core Commands

fasterq-dump - Download FASTQ (Recommended)

Fast, multithreaded FASTQ extraction. Preferred over fastq-dump.

# Download single SRA run as FASTQ
fasterq-dump SRR12345678

# Output: SRR12345678.fastq (single-end)
# Or: SRR12345678_1.fastq, SRR12345678_2.fastq (paired-end)

Key Options:

Option Description Example
-O / --outdir Output directory -O ./fastq/
-o / --outfile Output filename -o sample.fastq
-e / --threads Number of threads -e 8
-p / --progress Show progress bar -p
-S / --split-files Split paired reads (default) -S
-3 / --split-3 Also output unpaired reads -3
--skip-technical Skip technical reads --skip-technical
-t / --temp Temp directory -t /tmp
-f / --force Overwrite existing -f
# Common usage with options
fasterq-dump SRR12345678 -O ./data/ -e 8 -p --skip-technical

# Force split files (paired-end)
fasterq-dump SRR12345678 -S -O ./data/

Read the full file on GitHub · 367 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 3d ago First seen · 367 lines · 44 tokens per session scan D 64eaa2379631

Subscribe to this mod's changes

bio-sra-data is a skill published in the GitHub repository thesecondfox/skill (3 stars, last pushed 5mo ago), licensed MIT. It adds 44 tokens to every session and 2,662 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it D with 3 findings (asks for root, recursive force delete, runs shell commands). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

Related

Other skills, from other repositories

schema-exploration

Lists tables, describes columns and data types, identifies foreign key relationships, and maps entity relationships in a database. Use when the user asks about database schema, table structure, column types, what tables exist, ERD, foreign keys, or how entities relate.

langchain-ai/deepagents · 57 tokens

agent-platform-rag-engine-management

Manage and query Agent Platform RAG Engine Corpora and retrieve grounded contexts using the Google GenAI SDK. Use when listing RAG corpora or files, inspecting a corpus, retrieving contexts, or generating content grounded in a RAG corpus. Do not use for standard database queries (use SQL/Spanner skills), Google…

google/skills · 85 tokens

deploy-docker-compose

Run the Omnigent server as a Docker compose stack (server + Postgres) on any Docker host — your laptop, a VPS, EC2 by hand, or as the base layer of any container-platform deploy. Invoke when the user wants to build the image, bring up the compose stack, debug the stack on a host they already have, or extend the stack…

omnigent-ai/omnigent · 84 tokens

moderator-page-migration

Port a moderator page from the main Next.js app (src/pages/moderator/) into apps/moderator. Use when asked to migrate, move or cut over a /moderator/ page to the spoke, or to port its tRPC procedures and Prisma services to SvelteKit loads/actions and Kysely.

civitai/civitai · 71 tokens

dsql

Build with Aurora DSQL — manage schemas, execute queries, handle migrations, diagnose query plans, diagnose cluster performance, load data, and develop applications with a serverless, distributed SQL database. Covers IAM auth, multi-tenant patterns, MySQL-to-DSQL and PostgreSQL-to-DSQL schema conversion, foreign key…

awslabs/agent-plugins · 229 tokens

sql-translate

Translate SQL queries between database dialects (Snowflake, BigQuery, PostgreSQL, MySQL, etc.).

AltimateAI/altimate-code · 26 tokens