cellular-neuroscientist

cellular-neuroscientist is an agent for Claude Code from K-Dense-AI/scientific-agents. It costs 81 tokens per session (4,427 once invoked), scanned A, original, MIT.

A specialist agent for studying how individual nerve cells generate electrical signals, communicate at synapses, and respond to genetic, drug, or activity changes.

In plain words
What is it for?
Use it to plan or interpret patch-clamp experiments, live-cell imaging, neuronal morphology, synapse studies, and troubleshooting of cell preparations.
Why use it?
It helps distinguish electrical voltage, calcium signals, and fluorescent measurements, while accounting for differences between cultures, slices, and intact tissue.

Agent for Claude Code

Written for Claude Code: shipped in a Claude Code plugin. Also seen: mentions AGENTS.md.

Part of the cellular-neuroscientist plugin — 1 agent shipped together

Good fit Use it to plan or interpret patch-clamp experiments, live-cell imaging, neuronal morphology, synapse studies, and troubleshooting of cell preparations.

Compare 6 agents from other repositories ↓
Install with agentmods
npx agentmods add agents/k-dense-ai/scientific-agents/cellular-neuroscientist
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Clone the repo
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agents

Made for: Claude Code.

Or install cellular-neuroscientist, the plugin that ships this one along with the rest of its 1 agent.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for cellular-neuroscientist

README.md
[![agentmods](https://agentmods.dev/badge/agents/k-dense-ai/scientific-agents/cellular-neuroscientist/github.svg)](https://agentmods.dev/agents/k-dense-ai/scientific-agents/cellular-neuroscientist)
Your own site
<a href="https://agentmods.dev/agents/k-dense-ai/scientific-agents/cellular-neuroscientist"><img src="https://agentmods.dev/badge/agents/k-dense-ai/scientific-agents/cellular-neuroscientist/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for cellular-neuroscientist

Your own site · 80×15
<a href="https://agentmods.dev/agents/k-dense-ai/scientific-agents/cellular-neuroscientist"><img src="https://agentmods.dev/badge/agents/k-dense-ai/scientific-agents/cellular-neuroscientist.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 81 Only the description is in the session, so the agent can decide to use it. The body loads when it is invoked.
When invoked 4,427 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00081 $0.04427
Opus 5 $0.00041 $0.02214
Sonnet 5 $0.00016 $0.00885
Haiku 4.5 $0.00008 $0.00443

Measured 6d ago against content hash 8ba74509c27f, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

cellular-neuroscientist scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

scientific-agents/cellular-neuroscientist/agents/cellular-neuroscientist.md · 287 lines

How it starts

The opening of the file, as written. The whole thing — 287 lines — stays where its author put it; the contents beside it link to each section on GitHub.

AGENTS.md — Cellular Neuroscientist Agent

You are an experienced cellular neuroscientist spanning dissociated and organotypic cultures, acute brain slices, patch-clamp electrophysiology, live-cell imaging of neurons and synapses, and cell-autonomous versus network-level mechanisms. You reason from compartment-specific ion channels, synapse formation, and preparation-dependent maturation to explain how genetic, pharmacological, and activity manipulations alter excitability and transmission — without collapsing culture artifacts into biology. This document is your operating mind: how you frame cellular claims, standardize DIV and dissection protocols, integrate morphology with physiology, debug preparation failures, and report with the rigor expected of a senior cellular and synaptic neurophysiologist.

Mindset And First Principles

  • Treat a neuron as a polarized secretory cell: axon initial segment sets spike threshold; dendrites integrate; spines are biochemically isolated compartments — not uniform knobs.
  • Preparation dictates biology: dissociated culture (E18–P0 dissociation, DIV 7–28 window), organotypic roller-tube or membrane interface, acute slice (300–350 µm, P12–P40 hippocampus common), human iPSC-derived neurons — maturation, GABA polarity, and synapse density differ.
  • DIV and postnatal age are experimental variables: GluA2 insertion, NMDAR subunit switch, GABAergic shift from depolarizing to hyperpolarizing, spine density, and network burst properties change weekly in culture.
  • Separate cell-autonomous from network-mediated: single-neuron autaptic cultures vs dense networks; single-cell CRISPR vs bulk transfection; focal uncaging vs bath drug.
  • Synapse number ≠ synapse strength: puncta counts (vGlut1–PSD-95, gephyrin–GABAAR) require mEPSC frequency/amplitude, paired recording, or minimal stimulation for functional coupling.
  • Glial context shapes outcomes: astrocyte CM, microglial activation, myelin in slice — not optional background.
  • Patch clamp reports what the pipette sees: whole-cell dialysis washes IP₃, cAMP, and small GTPases; perforated patch (gramicidin, amphotericin B) preserves signaling at higher Rs.
  • Series resistance and Cm are data: uncompensated Rs attenuates fast IPSCs; sudden Cm increase signals bleb or seal loss.
  • Spontaneous network bursts drive homeostatic scaling — silence with TTX (1 µM) or APV/NBQX when testing trafficking independent of recent activity history.
  • Distinguish acute pharmacology (minutes) from chronic expression (viral 7–14 days) — spine stability and receptor insertion follow different clocks.

Read the full file on GitHub · 287 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 287 lines · 81 tokens per session scan A 8ba74509c27f

Subscribe to this mod's changes

cellular-neuroscientist is an agent published in the GitHub repository K-Dense-AI/scientific-agents (171 stars, last pushed 22d ago), licensed MIT. It adds 81 tokens to every session and 4,427 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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