lifesciences-research: Instructions file for Claude Code

CLAUDE.md

lifesciences-research CLAUDE.md is an instructions file for Claude Code from donbr/lifesciences-research. It costs 4,822 tokens per session, scanned A, original, MIT.

Repository instructions for a life-sciences project that provides agent-accessible interfaces to biological databases used in drug discovery and drug repurposing.

In plain words
What is it for?
Use them when developing or reviewing its FastMCP database wrappers, integrations, tests, and specification-driven workflow.
Why use it?
They explain the project structure, documentation, development process, and testing status so coding work follows the repository’s conventions.

Instructions file for Claude Code

Written for Claude Code: the file is CLAUDE.md. Also seen: mentions CLAUDE.md; mentions Claude Code.

This is donbr/lifesciences-research's own configuration. It tells Claude Code how to work on lifesciences-research itself, so it is not a mod to install elsewhere. Copy it as a starting point and replace the rules that are about this project. Everything lifesciences-research configures →

Reuse

Borrowing it

Nothing to install: this file belongs to donbr/lifesciences-research. Take a copy, put it at the same path in your own repository, and replace the rules that are about this project with yours.

Copy the file
curl -O https://raw.githubusercontent.com/donbr/lifesciences-research/main/CLAUDE.md
Clone the repo
git clone --depth 1 https://github.com/donbr/lifesciences-research

Made for: Claude Code.

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Per session 4,822 This file is loaded in full into every session.
When invoked 4,822 The same file — it is already loaded in full.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.04822 $0.04822
Opus 5 $0.02411 $0.02411
Sonnet 5 $0.00964 $0.00964
Haiku 4.5 $0.00482 $0.00482

Measured 9d ago against content hash e42f7e501889, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

lifesciences-research CLAUDE.md scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

- ClinicalTrials.gov server v0.1.0 - ✅ Complete (3 tools, 13 unit tests passing | Manual curl testing required due to Cloudflare blocking)
CLAUDE.md · 347 lines

How it starts

The opening of the file, as written. The whole thing — 347 lines — stays where its author put it; the contents beside it link to each section on GitHub.

CLAUDE.md

This file provides guidance to Claude Code (claude.ai/code) when working with code in this repository.

Project Overview

FastMCP wrappers for essential life sciences APIs, enabling LLM agents to query biological databases for drug discovery and repurposing.

Status:

  • HGNC server v0.1.0 - ✅ Complete (7 integration tests passing)
  • UniProt server v0.1.0 - ✅ Complete (12 integration tests passing, all 4 User Stories)
  • ChEMBL server v0.1.0 - ✅ Complete (62 tests: 20 integration + 42 unit, PR #10 merged)
  • Open Targets server v0.1.0 - ✅ Complete (9 tests, PR #11 merged)
  • DrugBank server v0.1.0 - ⛔ BLOCKED (33 unit tests, PR #12 open - API key required)
  • STRING server v0.1.0 - ✅ Complete (3 tools, 11 integration tests passing)
  • BioGRID server v0.1.0 - ✅ Complete (11 integration tests passing, all 4 User Stories)
  • Ensembl server v0.1.0 - ✅ Complete (86 tests: 62 unit + 24 integration)
  • Entrez server v0.1.0 - ✅ Complete (58 tests: 38 unit + 20 integration)
  • PubChem server v0.1.0 - ✅ Complete (85 tests: 66 unit + 19 integration)
  • IUPHAR/GtoPdb server v0.1.0 - ✅ Complete (59 tests: 48 integration + 11 unit, all 5 User Stories)
  • WikiPathways server v0.1.0 - ✅ Complete (4 tools, 17 integration tests passing)
  • ClinicalTrials.gov server v0.1.0 - ✅ Complete (3 tools, 13 unit tests passing | Manual curl testing required due to Cloudflare blocking)

Platform Skills:

  • lifesciences-crispr - ✅ Complete (BioGRID ORCS 5-phase synthetic lethality validation workflow)
  • lifesciences-genomics - ✅ Complete (Ensembl, NCBI, HGNC curl endpoints)
  • lifesciences-proteomics - ✅ Complete (UniProt, STRING, BioGRID curl endpoints)
  • lifesciences-pharmacology - ✅ Complete (ChEMBL, PubChem, DrugBank, IUPHAR curl endpoints)
  • lifesciences-clinical - ✅ Complete (Open Targets, ClinicalTrials.gov curl endpoints)
  • lifesciences-graph-builder - ✅ Complete (Fuzzy-to-Fact orchestration workflow)

Key Documentation

Document Purpose
docs/platform-engineering-rationale.md Start here - WHY we use Platform Engineering for agents
docs/competency-questions/competency-questions-catalog.md Research questions catalog for knowledge graph building
docs/adr/accepted/adr-001-v1.4.md Binding architecture specification (schemas, protocols, error codes)
docs/adr/accepted/adr-002-v1.0.md Project Skills (the "Hardware")
docs/adr/accepted/adr-003-v1.0.md SpecKit SDLC (the "Operating System")
docs/adr/accepted/adr-004-v1.0.md FastMCP Lifecycle Management (shutdown hook antipattern)
docs/adr/accepted/adr-005-v1.0.md Git Worktrees for Parallel Development
docs/adr/accepted/adr-006-v1.0.md Single Writer Package Architecture
docs/speckit-standard-prompt.md Standard prompt template for new MCP servers

Read the full file on GitHub · 347 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 347 lines · 4,822 tokens per session scan A e42f7e501889

Subscribe to this mod's changes

lifesciences-research CLAUDE.md is an instructions file published in the GitHub repository donbr/lifesciences-research (7 stars, last pushed 6d ago), licensed MIT. It adds 4,822 tokens to every session, about $0.0241 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

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