Local-first DNA and VCF analysis copilot for evidence-bound genomics workflows, confidence tiers, and Claude/Codex support.
22 files for Claude Code, Codex and OpenCode: annotate-variants, detect-build-normalize, generate-report, ingest-vcf and 18 more — 1,422 tokens loaded in every session.
AGENTS.md A 712 tok CLAUDE.md A 710 tok .claude/settings.json A — .claude/settings.json A — .claude/settings.json A — .agents/skills/annotate-variants/SKILL.md A 32 tok .agents/skills/detect-build-normalize/SKILL.md A 29 tok .agents/skills/generate-report/SKILL.md A 26 tok .agents/skills/ingest-vcf/SKILL.md A 36 tok .agents/skills/nextflow-runner/SKILL.md A 31 tok .agents/skills/pharmacogenomics/SKILL.md B 32 tok .agents/skills/polygenic-risk/SKILL.md A 34 tok .agents/skills/prioritize-findings/SKILL.md A 24 tok .agents/skills/query-variants/SKILL.md A 31 tok .agents/skills/setup-workstation/SKILL.md A 29 tok .claude/agents/annotation-worker.md A 14 tok .claude/agents/evidence-reviewer.md A 22 tok .claude/agents/explorer.md A 27 tok .claude/agents/orchestrator.md A 31 tok .claude/agents/qc-worker.md A 23 tok .claude/agents/report-writer.md A 21 tok .claude/agents/workflow-ops.md A 30 tok These files are 45ck/open-genome-agent's own configuration — they tell Claude Code, Codex and OpenCode how to work on this repository, so they are not mods to install elsewhere. Copy one as a starting point and replace the parts that are about this project.