trial-readout-analysis

trial-readout-analysis is a skill for Claude Code from agentii-ai/agentii-investment-intelligence. It costs 56 tokens per session (1,230 once invoked), scanned A, original, Apache-2.0.

A research workflow for evaluating clinical-trial results and estimating how financial markets may respond. It examines endpoints, statistics, safety, subgroups, missing data, and benefit versus risk, then compares the result with historical cases.

In plain words
What is it for?
Use it to review a trial readout, find weaknesses in its design or results, assess phase-three evidence, create a readout checklist, and estimate possible stock reactions for a biotech company.
Why use it?
It helps separate a promising trial result from evidence that is reliable, clinically meaningful, and likely to support approval. It also replaces a single prediction with base, optimistic, and pessimistic scenarios grounded in past events.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Part of the bio-pharm plugin — 7 skills shipped together

Good fit Use it to review a trial readout, find weaknesses in its design or results, assess phase-three evidence, create a readout checklist, and estimate possible stock reactions for a biotech company.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add agentii-ai/agentii-investment-intelligence --skill trial-readout-analysis
Clone the repo
git clone --depth 1 https://github.com/agentii-ai/agentii-investment-intelligence

Made for: Claude Code.

Or install bio-pharm, the plugin that ships this one along with the rest of its 7 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for trial-readout-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis/github.svg)](https://agentmods.dev/skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis)
Your own site
<a href="https://agentmods.dev/skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis"><img src="https://agentmods.dev/badge/skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for trial-readout-analysis

Your own site · 80×15
<a href="https://agentmods.dev/skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis"><img src="https://agentmods.dev/badge/skills/agentii-ai/agentii-investment-intelligence/trial-readout-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 56 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,230 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00056 $0.01230
Opus 5 $0.00028 $0.00615
Sonnet 5 $0.00011 $0.00246
Haiku 4.5 $0.00006 $0.00123

Measured 2d ago against content hash 47dd82675774, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

trial-readout-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

plugins/vertical-plugins/bio-pharm/skills/agentii/trial-readout-analysis/SKILL.md · 148 lines

How it starts

The opening of the file, as written. The whole thing — 148 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Methodology inspired by publicly taught clinical-trial frameworks; all text is an original paraphrase.

Defaults

Parameter Default Value Rationale
scrutiny_axes all six Safety/stats/subgroups/missing data/endpoints/benefit-risk
outcome_framing base/bull/bear Binary readouts need scenario sizing
reaction_context historical cases Size moves from past analogues

Preflight

Run canonical pre-flight per contracts/preflight.md. Propagate X-Agentii-Trace per contracts/x-agentii-trace-header.md.

Triggers

  • "Evaluate [ticker]'s upcoming trial readout."
  • "What should I look for in [trial]'s data?"
  • "Size the readout for [drug] phase 3."
  • "What did the AdCom-style scrutiny say about similar trials?"
  • "Base/bull/bear for [ticker]'s readout."
  • "Which endpoints matter for [trial]?"
  • "How has the market reacted to similar readouts?"
  • "Readout checklist for [ticker]."
  • "Is this trial design adequate?"
  • "What are the red flags in [trial]'s design?"

Production Grounding

  • Readout ≠ approval: phase-3 success is necessary but not sufficient; FDA re-analyzes sponsor data.
  • Apply the six scrutiny axes (safety signals, statistical adequacy, subgroup analyses, missing data, endpoint appropriateness, benefit-risk) — the 道/法 frameworks in references/knowledge-frameworks.md are the authoritative checklist.
  • Readout framing: readout design, then stock sizing (binary-risk expected value), then historical analogue comparison.

Data Source Priority

  1. search_clinical_trials / get_clinical_trial — design, status, endpoints, dates.
  2. search_documents / read_source_* — sponsor disclosure, prior data cuts.
  3. search_fda_approvals — regulatory history of the drug/program.
  4. Knowledge layer: search_investment_cases(event_type=trial_readout|adcom_vote) + strategies for judgment frameworks.

Methodology

Retrieval Scope

unstructured_document_search

Retrieval Strategy

  1. Pull the trial record (get_clinical_trial by NCT id, or search_clinical_trials by drug/ticker).
  2. Assess design + endpoint quality against scrutiny axes.
  3. Frame base/bull/bear outcomes with sizing.
  4. Ground in historical readout/adcom cases via knowledge tools.

Read the full file on GitHub · 148 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2d ago Changed · +1 lines 47dd82675774
  2. 7d ago First seen · 147 lines · 56 tokens per session scan A 019a0805f4b6

Subscribe to this mod's changes

trial-readout-analysis is a skill published in the GitHub repository agentii-ai/agentii-investment-intelligence (204 stars, last pushed 2d ago), licensed Apache-2.0. It adds 56 tokens to every session and 1,230 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-05.

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