biomni

biomni is a skill for Claude Code, Codex from AndyZhuang/Opentest. It costs 82 tokens per session (2,445 once invoked), scanned A, a copy of biomni, MIT.

A biomedical research framework that helps an AI agent work through complex tasks in areas such as genomics, drug discovery, molecular biology, and clinical analysis.

In plain words
What is it for?
It supports tasks such as designing CRISPR screens, analyzing single-cell RNA sequencing data, predicting drug properties, and interpreting genome-wide association studies.
Why use it?
Biomedical questions often require several analysis steps and information from different scientific databases and research areas.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit It supports tasks such as designing CRISPR screens, analyzing single-cell RNA sequencing data, predicting drug properties, and interpreting genome-wide association studies.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/andyzhuang/opentest/biomni
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AndyZhuang/Opentest --skill biomni
Clone the repo
git clone --depth 1 https://github.com/AndyZhuang/Opentest

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for biomni

README.md
[![agentmods](https://agentmods.dev/badge/skills/andyzhuang/opentest/biomni/github.svg)](https://agentmods.dev/skills/andyzhuang/opentest/biomni)
Your own site
<a href="https://agentmods.dev/skills/andyzhuang/opentest/biomni"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/biomni/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for biomni

Your own site · 80×15
<a href="https://agentmods.dev/skills/andyzhuang/opentest/biomni"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/biomni.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 82 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,445 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 100% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00082 $0.02445
Opus 5 $0.00041 $0.01222
Sonnet 5 $0.00016 $0.00489
Haiku 4.5 $0.00008 $0.00245

Measured 11d ago against content hash f85aececbfbb, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

biomni scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 11d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

100% identical to biomni — 0 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/labclaw/bio/biomni/SKILL.md · 315 lines

How it starts

The opening of the file, as written. The whole thing — 315 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Biomni

Overview

Biomni is an open-source biomedical AI agent framework from Stanford's SNAP lab that autonomously executes complex research tasks across biomedical domains. Use this skill when working on multi-step biological reasoning tasks, analyzing biomedical data, or conducting research spanning genomics, drug discovery, molecular biology, and clinical analysis.

Core Capabilities

Biomni excels at:

  1. Multi-step biological reasoning - Autonomous task decomposition and planning for complex biomedical queries
  2. Code generation and execution - Dynamic analysis pipeline creation for data processing
  3. Knowledge retrieval - Access to ~11GB of integrated biomedical databases and literature
  4. Cross-domain problem solving - Unified interface for genomics, proteomics, drug discovery, and clinical tasks

When to Use This Skill

Use biomni for:

  • CRISPR screening - Design screens, prioritize genes, analyze knockout effects
  • Single-cell RNA-seq - Cell type annotation, differential expression, trajectory analysis
  • Drug discovery - ADMET prediction, target identification, compound optimization
  • GWAS analysis - Variant interpretation, causal gene identification, pathway enrichment
  • Clinical genomics - Rare disease diagnosis, variant pathogenicity, phenotype-genotype mapping
  • Lab protocols - Protocol optimization, literature synthesis, experimental design

Quick Start

Installation and Setup

Install Biomni and configure API keys for LLM providers:

uv pip install biomni --upgrade

Configure API keys (store in .env file or environment variables):

export ANTHROPIC_API_KEY="your-key-here"
# Optional: OpenAI, Azure, Google, Groq, AWS Bedrock keys

Use scripts/setup_environment.py for interactive setup assistance.

Basic Usage Pattern

from biomni.agent import A1

# Initialize agent with data path and LLM choice
agent = A1(path='./data', llm='claude-sonnet-4-20250514')

# Execute biomedical task autonomously
agent.go("Your biomedical research question or task")

# Save conversation history and results
agent.save_conversation_history("report.pdf")

Read the full file on GitHub · 315 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 11d ago First seen · 315 lines · 82 tokens per session scan A f85aececbfbb

Subscribe to this mod's changes

biomni is a skill published in the GitHub repository AndyZhuang/Opentest (22 stars, last pushed 6mo ago), licensed MIT. It adds 82 tokens to every session and 2,445 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. It is 100% identical to biomni, differing in 0 lines, and is treated as a copy.

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