tooluniverse-clinical-guidelines

Clinical Guidelines Search & Retrieval

Search and retrieve evidence-based clinical practice guidelines from 12+ authoritative sources spanning 41 tools. Covers disease management guidelines, society recommendations, pharmacogenomics guidance, and patient resources.

KEY PRINCIPLES:

1. Multi-source search — Search ≥3 databases in parallel for comprehensive coverage
2. Source-appropriate queries — Match query style to each database's strengths
3. Condition + society specific — When user names a disease or society, use targeted tools
4. English queries first — Use English medical terms in all tool calls; respond in user's language
5. Cite sources — Every guideline result must include source organization and URL

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When to Use

Apply when user asks:

• "What are the guidelines for [condition]?"
• "What does [ADA/AHA/NCCN/NICE/WHO] say about [topic]?"
• "Standard of care for [disease]?"
• "Drug-gene interactions for [drug/gene]?" (pharmacogenomics)
• "Screening recommendations for [condition]?"
• "Is there a guideline for [clinical question]?"
• "What do guidelines say about [treatment/drug]?"
• "Clinical recommendations for [oncology topic]?"

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Phase 0: Tool Verification (MANDATORY FIRST STEP)

Before searching, verify tools load:

from tooluniverse import ToolUniverse
tu = ToolUniverse()
tu.load_tools()
assert hasattr(tu.tools, 'NICE_Clinical_Guidelines_Search')

Correct call pattern (use either approach):

# Option A: direct attribute access
result = tu.tools.NICE_Clinical_Guidelines_Search(query='diabetes', limit=5)

# Option B: run_one_function
result = tu.run_one_function({'name': 'NICE_Clinical_Guidelines_Search', 'arguments': {'query': 'diabetes', 'limit': 5}})

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Phase 1: Identify Query Strategy

Determine which tools to use based on the user's question:

Query type	Primary tools	Secondary tools
General disease guideline	NICE, TRIP, GIN	PubMed, EuropePMC, CMA
Cardiology	AHA_ACC_search_guidelines, AHA_list_guidelines	NICE, TRIP
Oncology	NCCN_search_guidelines, NCCN_list_patient_guidelines	NICE, GIN
Diabetes / endocrinology	ADA_search_standards, ADA_list_standards_sections	NICE, SIGN
Pharmacogenomics	CPIC_get_gene_drug_pairs, CPIC_list_guidelines	CPIC_get_gene_info
Canadian guidelines	CMA_Guidelines_Search, CTFPHC_search_guidelines	—
Scottish/UK guidelines	SIGN_search_guidelines, NICE	CMA
International guidelines	GIN_Guidelines_Search	OpenAlex, EuropePMC
Living guidelines	MAGICapp_list_guidelines	GIN
Full-text retrieval	NICE_Guideline_Full_Text, WHO_Guideline_Full_Text, AHA_ACC_get_guideline	—