tooluniverse-gwas-study-explorer

tooluniverse-gwas-study-explorer is a skill for Claude Code, Codex from AndyZhuang/Opentest. It costs 88 tokens per session (2,709 once invoked), scanned A, original, MIT.

A tool for comparing genome-wide association studies (GWAS), which look for links between genetic differences and traits or diseases.

In plain words
What is it for?
Use it to compare GWAS designs and cohorts, combine genetic effect estimates in meta-analyses, measure differences between studies, and assess replicated findings.
Why use it?
It brings study results together so researchers can judge whether findings agree, apply across populations, and replicate in other groups.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to compare GWAS designs and cohorts, combine genetic effect estimates in meta-analyses, measure differences between studies, and assess replicated findings.

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Install with agentmods
npx agentmods add skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AndyZhuang/Opentest --skill tooluniverse-gwas-study-explorer
Clone the repo
git clone --depth 1 https://github.com/AndyZhuang/Opentest

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for tooluniverse-gwas-study-explorer

README.md
[![agentmods](https://agentmods.dev/badge/skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer/github.svg)](https://agentmods.dev/skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer)
Your own site
<a href="https://agentmods.dev/skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for tooluniverse-gwas-study-explorer

Your own site · 80×15
<a href="https://agentmods.dev/skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/tooluniverse-gwas-study-explorer.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 88 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,709 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00088 $0.02709
Opus 5 $0.00044 $0.01354
Sonnet 5 $0.00018 $0.00542
Haiku 4.5 $0.00009 $0.00271

Measured 8d ago against content hash fd47a721fe88, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

tooluniverse-gwas-study-explorer scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/labclaw/bio/tooluniverse-gwas-study-explorer/SKILL.md · 343 lines

How it starts

The opening of the file, as written. The whole thing — 343 lines — stays where its author put it; the contents beside it link to each section on GitHub.

GWAS Study Deep Dive & Meta-Analysis

Compare GWAS studies, perform meta-analyses, and assess replication across cohorts


Overview

The GWAS Study Deep Dive & Meta-Analysis skill enables comprehensive comparison of genome-wide association studies (GWAS) for the same trait, meta-analysis of genetic loci across studies, and systematic assessment of replication and study quality. It integrates data from the NHGRI-EBI GWAS Catalog and Open Targets Genetics to provide a complete picture of the genetic architecture of complex traits.

Key Capabilities

  1. Study Comparison: Compare all GWAS studies for a trait, assessing sample sizes, ancestries, and platforms
  2. Meta-Analysis: Aggregate effect sizes across studies and calculate heterogeneity statistics
  3. Replication Assessment: Identify replicated vs novel findings across discovery and replication cohorts
  4. Quality Evaluation: Assess statistical power, ancestry diversity, and data availability

Use Cases

1. Comprehensive Trait Analysis

Scenario: "I want to understand all available GWAS data for type 2 diabetes"

Workflow:

  • Search for all T2D studies in GWAS Catalog
  • Filter by sample size and ancestry
  • Extract top associations from each study
  • Identify consistently replicated loci
  • Assess ancestry-specific effects

Outcome: Complete landscape of T2D genetics with replicated findings and population-specific signals

2. Locus-Specific Meta-Analysis

Scenario: "Is the TCF7L2 association with T2D consistent across all studies?"

Workflow:

  • Retrieve all TCF7L2 (rs7903146) associations for T2D
  • Calculate combined effect size and p-value
  • Assess heterogeneity (I² statistic)
  • Generate forest plot data
  • Interpret heterogeneity level

Outcome: Quantitative assessment of effect size consistency with heterogeneity interpretation

3. Replication Analysis

Scenario: "Which findings from the discovery cohort replicated in the independent sample?"

Read the full file on GitHub · 343 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 343 lines · 88 tokens per session scan A fd47a721fe88

Subscribe to this mod's changes

tooluniverse-gwas-study-explorer is a skill published in the GitHub repository AndyZhuang/Opentest (22 stars, last pushed 6mo ago), licensed MIT. It adds 88 tokens to every session and 2,709 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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