tooluniverse-precision-medicine-stratification

tooluniverse-precision-medicine-stratification is a skill for Claude Code, Codex from AndyZhuang/Opentest. It costs 193 tokens per session (13,762 once invoked), scanned A, original, MIT.

A clinical analysis workflow that combines a patient's genetic, tumor, treatment, and other health data to estimate risks and suggest personalised care options.

In plain words
What is it for?
Use it to stratify patients by risk, review pharmacogenomic drug and dose choices, and prepare evidence-referenced treatment strategies for cancer, metabolic, or rare diseases.
Why use it?
It brings several kinds of medical evidence together in one structured assessment, so important factors are less likely to be considered separately or missed.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to stratify patients by risk, review pharmacogenomic drug and dose choices, and prepare evidence-referenced treatment strategies for cancer, metabolic, or rare diseases.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AndyZhuang/Opentest --skill tooluniverse-precision-medicine-stratification
Clone the repo
git clone --depth 1 https://github.com/AndyZhuang/Opentest

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for tooluniverse-precision-medicine-stratification

README.md
[![agentmods](https://agentmods.dev/badge/skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification/github.svg)](https://agentmods.dev/skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification)
Your own site
<a href="https://agentmods.dev/skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for tooluniverse-precision-medicine-stratification

Your own site · 80×15
<a href="https://agentmods.dev/skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/tooluniverse-precision-medicine-stratification.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 193 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 13,762 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00193 $0.13762
Opus 5 $0.00097 $0.06881
Sonnet 5 $0.00039 $0.02752
Haiku 4.5 $0.00019 $0.01376

Measured 9d ago against content hash b90211d88655, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

tooluniverse-precision-medicine-stratification scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/labclaw/med/tooluniverse-precision-medicine-stratification/SKILL.md · 1,144 lines

How it starts

The opening of the file, as written. The whole thing — 1,144 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Precision Medicine Patient Stratification

Transform patient genomic and clinical profiles into actionable risk stratification, treatment recommendations, and personalized therapeutic strategies. Integrates germline genetics, somatic alterations, pharmacogenomics, pathway biology, and clinical evidence to produce a quantitative risk score with tiered management recommendations.

KEY PRINCIPLES:

  1. Report-first approach - Create report file FIRST, then populate progressively
  2. Disease-specific logic - Cancer vs metabolic vs rare disease pipelines diverge at Phase 2
  3. Multi-level integration - Germline + somatic + expression + clinical data layers
  4. Evidence-graded - Every finding has an evidence tier (T1-T4)
  5. Quantitative output - Precision Medicine Risk Score (0-100) with transparent components
  6. Pharmacogenomic guidance - Drug selection AND dosing recommendations
  7. Guideline-concordant - Reference NCCN, ACC/AHA, ADA, and other guidelines
  8. Source-referenced - Every statement cites the tool/database source
  9. Completeness checklist - Mandatory section showing data availability and analysis coverage
  10. English-first queries - Always use English terms in tool calls. Respond in user's language

When to Use

Apply when user asks:

  • "Stratify this breast cancer patient: ER+/HER2-, BRCA1 mutation, stage II"
  • "What is the risk profile for this diabetes patient with HbA1c 8.5 and CYP2C19 poor metabolizer?"
  • "NSCLC patient with EGFR L858R, stage IV, TMB 25 - treatment strategy?"
  • "Predict prognosis and recommend treatment for this cardiovascular patient"
  • "Patient has Marfan syndrome with FBN1 mutation - risk stratification"
  • "Alzheimer's risk assessment: APOE e4/e4, family history positive"
  • "Personalized treatment plan for type 2 diabetes with genetic risk factors"
  • "Which therapy is best for this patient's molecular profile?"

NOT for (use other skills instead):

  • Single variant interpretation -> Use tooluniverse-variant-interpretation or tooluniverse-cancer-variant-interpretation
  • Immunotherapy-specific prediction -> Use tooluniverse-immunotherapy-response-prediction
  • Drug safety profiling only -> Use tooluniverse-adverse-event-detection
  • Target validation -> Use tooluniverse-drug-target-validation
  • Clinical trial search only -> Use tooluniverse-clinical-trial-matching
  • Drug-drug interaction analysis only -> Use tooluniverse-drug-drug-interaction
  • PRS calculation only -> Use tooluniverse-polygenic-risk-score

Read the full file on GitHub · 1,144 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 1,144 lines · 193 tokens per session scan A b90211d88655

Subscribe to this mod's changes

tooluniverse-precision-medicine-stratification is a skill published in the GitHub repository AndyZhuang/Opentest (22 stars, last pushed 6mo ago), licensed MIT. It adds 193 tokens to every session and 13,762 once invoked, about $0.0010 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

Related

Other skills, from other repositories

arboreto

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for…

K-Dense-AI/scientific-agent-skills · 66 tokens

pyhealth

Build clinical/healthcare deep-learning pipelines with PyHealth — loading EHR/signal/imaging datasets (MIMIC-III/IV, eICU, OMOP, SleepEDF, ChestXray14, EHRShot), defining tasks (mortality, readmission, length-of-stay, drug recommendation, sleep staging, ICD coding, EEG events), instantiating models (Transformer…

K-Dense-AI/scientific-agent-skills · 216 tokens

torchdrug

Build and troubleshoot TorchDrug 0.2.1 workflows for molecular graphs, property prediction, self-supervised pretraining, molecule generation, retrosynthesis, protein representation learning, and knowledge graph reasoning. Use when code imports torchdrug or needs its datasets, models, tasks, or Engine.

K-Dense-AI/scientific-agent-skills · 61 tokens

deepspot-m

Generate transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Use when you need spatial gene expression in log1p-CPM for 224x224 tiles at about 20x, want to query protein-coding genes by symbol instead of a fixed panel, or want to run prediction across a whole slide after tiling with…

K-Dense-AI/scientific-agent-skills · 80 tokens

nemo-mbridge-perf-expert-parallel-overlap

Validate and use MoE expert-parallel communication overlap in Megatron-Bridge, including overlapmoeexpertparallelcomm, delaywgradcompute, and flex dispatcher backends such as DeepEP and HybridEP.

NVIDIA/skills · 56 tokens

pick-a-pii-model

Select an on-device OpenMed PII model from the committed registry by language, runtime format, and size budget, then require recall validation before deployment. Use when an agent must choose a local PII detector for CPU, Apple Silicon, or a mobile export without relying on live model discovery.

maziyarpanahi/openmed · 64 tokens