genomics-variant-interpretation

genomics-variant-interpretation is a skill for Claude Code, Codex from aws-samples/amazon-bedrock-agents-healthcare-lifesciences. It costs 49 tokens per session (1,400 once invoked), scanned A, original, MIT-0.

A workflow for interpreting genetic variants—DNA differences that may affect health—from VCF files and related databases.

In plain words
What is it for?
Use it to classify variants with ClinVar and VEP, compare frequencies from the 1000 Genomes project, and create reports for genetic counseling.
Why use it?
It helps turn variant data into classifications and reports by comparing annotations, clinical records, and population frequencies.

Skill for Claude CodeCodex ✓ vendor

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

Good fit Use it to classify variants with ClinVar and VEP, compare frequencies from the 1000 Genomes project, and create reports for genetic counseling.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation
About the project

Healthcare and Life Sciences Agents Toolkit is an AWS library of domain-specific AI capabilities for healthcare and life sciences workflows, including reference agents, reusable skills, and MCP tools. Builders, researchers, clinicians, scientists, and platform teams use it for tasks such as drug research, clinical trials, genomics, and commercialization. The catalogue add-ons expose parts of the toolkit as portable skills and MCP tools for coding assistants and other platforms.

aws-samples/amazon-bedrock-agents-healthcare-lifesciences · 275 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aws-samples/amazon-bedrock-agents-healthcare-lifesciences --skill genomics-variant-interpretation
Clone the repo
git clone --depth 1 https://github.com/aws-samples/amazon-bedrock-agents-healthcare-lifesciences

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for genomics-variant-interpretation

README.md
[![agentmods](https://agentmods.dev/badge/skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation/github.svg)](https://agentmods.dev/skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation)
Your own site
<a href="https://agentmods.dev/skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation"><img src="https://agentmods.dev/badge/skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for genomics-variant-interpretation

Your own site · 80×15
<a href="https://agentmods.dev/skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation"><img src="https://agentmods.dev/badge/skills/aws-samples/amazon-bedrock-agents-healthcare-lifesciences/genomics-variant-interpretation.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 49 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,400 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00049 $0.01400
Opus 5.5 $0.00020 $0.00560
Sonnet 5.5 $0.00010 $0.00280
Haiku 4.5 $0.00005 $0.00140

Measured 2mo ago against content hash a5e37518414b, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

genomics-variant-interpretation scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2mo ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/genomics-variant-interpretation/SKILL.md · 144 lines

The source is not reproduced here

Licensed MIT-0

The repository is licensed MIT-0, which this catalogue does not treat as permission to reproduce the file. Read it at the source.

Read it on GitHub

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2mo ago First seen · 144 lines · 49 tokens per session scan A a5e37518414b

Subscribe to this mod's changes

genomics-variant-interpretation is a skill published in the GitHub repository aws-samples/amazon-bedrock-agents-healthcare-lifesciences (275 stars, last pushed 8d ago), licensed MIT-0. It adds 49 tokens to every session and 1,400 once invoked, about $0.0002 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

genomics-variant-interpretation compared with skills from other repositories

genomics-variant-interpretation next to 6 skills from other repositories
ModTypeStarsLast pushLicenceScanTokensWorks with
genomics-variant-interpretationaws-samples/amazon-bedrock-agents-healthcare-lifesciencesSkill2758d agoMIT-0A49Claude Code, Codex
instrument-data-to-allotropeanthropics/knowledge-work-pluginsSkill35k2d agoApache-2.0A123Claude Code
exploratory-data-analysisK-Dense-AI/scientific-agent-skillsSkill56k4d agoMITA83Claude Code
matlabK-Dense-AI/scientific-agent-skillsSkill56k4d agoMITA44Claude Code
phylogeneticsK-Dense-AI/scientific-agent-skillsSkill56k4d agoMITA71Claude Code, Codex
research-engineerdavila7/claude-code-templatesSkill33ktodayMITA43Claude Code, Codex
mapping-to-snomedmaziyarpanahi/openmedSkill5.8kyesterdayApache-2.0A205Claude Code