indication-dossier

A workflow for building an evidence-based biomedical report about a disease, treatment target, biomarker, patient group, or therapy. It separates human studies, laboratory evidence, clinical trials, safety information, and unanswered questions.

In plain words
What is it for?
Use it to prepare an indication dossier covering disease biology, treatment rationale, patient segments, biomarkers, trials, existing drugs, competing approaches, and evidence relevant to clinical development.
Why use it?
It helps researchers judge how strong and reproducible the evidence is without presenting limited findings as medical advice.

Skill for Claude CodeCodex

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/companion-inc/feynman/indication-dossier
Any agent
npx skills add companion-inc/feynman --skill indication-dossier
Clone the repo
git clone --depth 1 https://github.com/companion-inc/feynman

Made for: Claude Code, Codex.

Per session 43 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 215 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5 $0.00043 $0.00215
Opus 5 $0.00022 $0.00108
Sonnet 5 $0.00009 $0.00043
Haiku 4.5 $0.00004 $0.00021

Measured yesterday against content hash a53108d0a679, method: parsed. Prices are Anthropic first-party input rates as of 2026-08-30, from the pricing page.

Security

Grade A, and why

indication-dossier scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured yesterday.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/indication-dossier/SKILL.md · 19 lines

What it actually says

Indication Dossier

Use this skill to assemble a biomedical evidence packet for a disease, target, mechanism, biomarker, or therapy.

Workflow:

  1. Define the indication, patient segment, intervention or target, and decision the dossier must support.
  2. Gather evidence from literature, clinical trials, Open Targets, ChEMBL, CIViC, ClinGen, cBioPortal, DepMap/COSMIC-compatible sources, and other Feynman Bio Tools as relevant.
  3. Separate human evidence, model-system evidence, mechanism, biomarkers, clinical precedent, safety, and open questions.
  4. Rank claims by source strength and reproducibility. Flag missing cohorts, confounders, and assay limitations.
  5. Save the dossier and provenance sidecar in outputs/.

Do not turn sparse evidence into a clinical recommendation.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. yesterday First seen · 19 lines · 43 tokens per session scan A a53108d0a679

Subscribe to this mod's changes

indication-dossier is a skill published in the GitHub repository companion-inc/feynman (8,629 stars, last pushed 5d ago), licensed MIT. It adds 43 tokens to every session and 215 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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