hypogenic

hypogenic is a skill for Claude Code, Codex from crazymsn/academic-skills. It costs 69 tokens per session (4,928 once invoked), scanned A, a copy of hypogenic, MIT.

A research tool that uses language models and tabular data to generate and test hypotheses. A hypothesis is a proposed explanation or pattern that can be checked against evidence.

In plain words
What is it for?
Use it to explore patterns in datasets, combine literature findings with data-driven ideas, generate a set of hypotheses, and run inference on those hypotheses.
Why use it?
It reduces the manual effort of thinking up many testable explanations and comparing them with both existing research and dataset patterns.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Needs its repository: it runs a file that does not travel with it, so clone the repository first. The line is bash ./modules/setup_grobid.sh.

Good fit Use it to explore patterns in datasets, combine literature findings with data-driven ideas, generate a set of hypotheses, and run inference on those hypotheses.

Compare 6 skills from other repositories ↓
Install

Getting it into your agent

It runs from inside its repository, so the clone comes first — what it calls does not travel with the file alone.

Clone the repo
git clone --depth 1 https://github.com/crazymsn/academic-skills
agentmods
npx agentmods add skills/crazymsn/academic-skills/hypogenic

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for hypogenic

README.md
[![agentmods](https://agentmods.dev/badge/skills/crazymsn/academic-skills/hypogenic/github.svg)](https://agentmods.dev/skills/crazymsn/academic-skills/hypogenic)
Your own site
<a href="https://agentmods.dev/skills/crazymsn/academic-skills/hypogenic"><img src="https://agentmods.dev/badge/skills/crazymsn/academic-skills/hypogenic/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for hypogenic

Your own site · 80×15
<a href="https://agentmods.dev/skills/crazymsn/academic-skills/hypogenic"><img src="https://agentmods.dev/badge/skills/crazymsn/academic-skills/hypogenic.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 69 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,928 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 97% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00069 $0.04928
Opus 5 $0.00034 $0.02464
Sonnet 5 $0.00014 $0.00986
Haiku 4.5 $0.00007 $0.00493

Measured 9d ago against content hash 611ae3cacaba, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

hypogenic scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

97% identical to hypogenic — 9 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

academic-skills/hypogenic/SKILL.md · 654 lines

How it starts

The opening of the file, as written. The whole thing — 654 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Hypogenic

Overview

Hypogenic provides automated hypothesis generation and testing using large language models to accelerate scientific discovery. The framework supports three approaches: HypoGeniC (data-driven hypothesis generation), HypoRefine (synergistic literature and data integration), and Union methods (mechanistic combination of literature and data-driven hypotheses).

Quick Start

Get started with Hypogenic in minutes:

# Install the package
uv pip install hypogenic

# Clone example datasets
git clone https://github.com/ChicagoHAI/HypoGeniC-datasets.git ./data

# Run basic hypothesis generation
hypogenic_generation --config ./data/your_task/config.yaml --method hypogenic --num_hypotheses 20

# Run inference on generated hypotheses
hypogenic_inference --config ./data/your_task/config.yaml --hypotheses output/hypotheses.json

Or use Python API:

from hypogenic import BaseTask

# Create task with your configuration
task = BaseTask(config_path="./data/your_task/config.yaml")

# Generate hypotheses
task.generate_hypotheses(method="hypogenic", num_hypotheses=20)

# Run inference
results = task.inference(hypothesis_bank="./output/hypotheses.json")

When to Use This Skill

Use this skill when working on:

  • Generating scientific hypotheses from observational datasets
  • Testing multiple competing hypotheses systematically
  • Combining literature insights with empirical patterns
  • Accelerating research discovery through automated hypothesis ideation
  • Domains requiring hypothesis-driven analysis: deception detection, AI-generated content identification, mental health indicators, predictive modeling, or other empirical research

Key Features

Automated Hypothesis Generation

  • Generate 10-20+ testable hypotheses from data in minutes
  • Iterative refinement based on validation performance
  • Support for both API-based (OpenAI, Anthropic) and local LLMs

Literature Integration

  • Extract insights from research papers via PDF processing
  • Combine theoretical foundations with empirical patterns
  • Systematic literature-to-hypothesis pipeline with GROBID

Read the full file on GitHub · 654 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 654 lines · 69 tokens per session scan A 611ae3cacaba

Subscribe to this mod's changes

hypogenic is a skill published in the GitHub repository crazymsn/academic-skills (22 stars, last pushed 3mo ago), licensed MIT. It adds 69 tokens to every session and 4,928 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. It is 97% identical to hypogenic, differing in 9 lines, and is treated as a copy.

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