pyopenms

pyopenms is a skill for Claude Code from dralkh/iktinah. It costs 74 tokens per session (2,052 once invoked), scanned A, a copy of pyopenms, MIT.

A Python platform for analyzing mass-spectrometry data, which measures molecules by their mass and charge, in proteomics and metabolomics.

In plain words
What is it for?
Use it to inspect and convert mass-spectrometry files, detect features, identify peptides and proteins, quantify samples, and build analysis pipelines.
Why use it?
It brings file handling, spectrum processing, molecule identification, and quantification into one workflow for complex LC-MS/MS experiments.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Good fit Use it to inspect and convert mass-spectrometry files, detect features, identify peptides and proteins, quantify samples, and build analysis pipelines.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/dralkh/iktinah/pyopenms
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add dralkh/iktinah --skill pyopenms
Clone the repo
git clone --depth 1 https://github.com/dralkh/iktinah

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for pyopenms

README.md
[![agentmods](https://agentmods.dev/badge/skills/dralkh/iktinah/pyopenms/github.svg)](https://agentmods.dev/skills/dralkh/iktinah/pyopenms)
Your own site
<a href="https://agentmods.dev/skills/dralkh/iktinah/pyopenms"><img src="https://agentmods.dev/badge/skills/dralkh/iktinah/pyopenms/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for pyopenms

Your own site · 80×15
<a href="https://agentmods.dev/skills/dralkh/iktinah/pyopenms"><img src="https://agentmods.dev/badge/skills/dralkh/iktinah/pyopenms.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 74 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,052 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 88% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00074 $0.02052
Opus 5 $0.00037 $0.01026
Sonnet 5 $0.00015 $0.00410
Haiku 4.5 $0.00007 $0.00205

Measured 8d ago against content hash 822bb1423fe2, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

pyopenms scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 16 executable files (scripts/accurate_mass_search.py, scripts/align_link_quantify.py, scripts/consensus_to_matrix.py, …), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

88% identical to pyopenms — 21 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/pyopenms/SKILL.md · 178 lines

How it starts

The opening of the file, as written. The whole thing — 178 lines — stays where its author put it; the contents beside it link to each section on GitHub.

PyOpenMS

Overview

PyOpenMS provides Python bindings to the OpenMS library for computational mass spectrometry, enabling analysis of proteomics and metabolomics data. Use it to read/write MS file formats, process raw spectra, detect and quantify features, identify peptides and proteins, and run end-to-end LC-MS/MS pipelines.

This skill ships ready-to-run scripts in scripts/ covering the most common high-level workflows. Prefer running a script over writing new code—each is a parameterized CLI tool that handles loading, processing, and export. Drop into the Python API (and the references/) only when no script fits.

Installation

uv pip install pyopenms

Verify (note: __version__ works, but the bundled binary prints a one-line memory-status notice on import that is harmless):

import pyopenms as ms
print(ms.__version__)  # 3.5.0

Scripts (start here)

Run with python scripts/<name>.py --help for full options. All accept standard MS file formats and write featureXML/consensusXML/CSV/mzTab/PNG as appropriate.

Inspect & convert

Script What it does
inspect_ms_data.py Summarize any mzML/mzXML/featureXML/consensusXML/idXML (counts, RT/m/z ranges, TIC, metadata); optional per-spectrum CSV.
convert_format.py Convert between mzML/mzXML/MGF with optional MS-level, RT, and intensity filtering.
process_spectra.py Configurable signal-processing chain: smoothing (Gauss/SGolay), centroiding (PeakPickerHiRes), normalization, S/N and intensity thresholds.

Feature detection & quantification

Script What it does
detect_features_metabo.py Untargeted metabolomics feature finding: MassTraceDetection → ElutionPeakDetection → FeatureFindingMetabo.
detect_features_centroided.py Peptide/centroided feature detection via FeatureFinderAlgorithmPicked.
align_link_quantify.py Multi-sample pipeline: detect (or load) features → RT alignment → consensus linking → quant matrix CSV.
consensus_to_matrix.py consensusXML → wide intensity matrix + metadata, with optional median/quantile normalization and long format.

Read the full file on GitHub · 178 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 178 lines · 74 tokens per session scan A 822bb1423fe2

Subscribe to this mod's changes

pyopenms is a skill published in the GitHub repository dralkh/iktinah (77 stars, last pushed 2mo ago), licensed MIT. It adds 74 tokens to every session and 2,052 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. It is 88% identical to pyopenms, differing in 21 lines, and is treated as a copy.

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