bayesian_finemapping_with_deep_vi

bayesian_finemapping_with_deep_vi is a skill for Claude Code from GGbond-bo/MemOmics-Agent. It costs 40 tokens per session (1,710 once invoked), scanned A, original, MIT.

A Bayesian method for fine-mapping genetic variants from GWAS summary statistics and linkage disequilibrium data. GWAS studies associations between genetic variants and traits; fine-mapping narrows those associations to likely causal variants.

In plain words
What is it for?
Use it to analyse GWAS summary files and LD matrices, estimate posterior inclusion probabilities, and produce credible sets such as 95% sets.
Why use it?
It helps distinguish which variants in a correlated group are most likely to affect a trait. It also calculates the probability assigned to each variant and groups variants into credible sets.

Skill for Claude Code

Written for Claude Code: when-to-use in frontmatter.

Good fit Use it to analyse GWAS summary files and LD matrices, estimate posterior inclusion probabilities, and produce credible sets such as 95% sets.

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Install with agentmods
npx agentmods add skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add GGbond-bo/MemOmics-Agent --skill bayesian_finemapping_with_deep_vi
Clone the repo
git clone --depth 1 https://github.com/GGbond-bo/MemOmics-Agent

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bayesian_finemapping_with_deep_vi

README.md
[![agentmods](https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi/github.svg)](https://agentmods.dev/skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi)
Your own site
<a href="https://agentmods.dev/skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi"><img src="https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bayesian_finemapping_with_deep_vi

Your own site · 80×15
<a href="https://agentmods.dev/skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi"><img src="https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/bayesian_finemapping_with_deep_vi.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 40 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,710 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00040 $0.01710
Opus 5 $0.00020 $0.00855
Sonnet 5 $0.00008 $0.00342
Haiku 4.5 $0.00004 $0.00171

Measured 9d ago against content hash c178af9099ff, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

bayesian_finemapping_with_deep_vi scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/run.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

hermes_home/skills/bioinformatics/bayesian_finemapping_with_deep_vi/SKILL.md · 129 lines

How it starts

The opening of the file, as written. The whole thing — 129 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Bayesian Finemapping With Deep Vi

Performs Bayesian fine-mapping from GWAS summary statistics using deep variational inference to compute posterior inclusion probabilities and credible sets for putative causal variants.

When to Use

When you need bayesian finemapping with deep vi analysis

Parameters

Parameter Default Notes
gwas_summary_path [Required] Path to CSV or TSV file containing GWAS summary statistics with variant_id, effect_size, pvalue, and optional se columns (str)
ld_matrix [Required] Linkage disequilibrium matrix with pairwise correlations between variants (numpy.ndarray)
n_iterations [Optional] Number of training iterations for the variational inference algorithm (default: 5000)
learning_rate [Optional] Learning rate for the optimization algorithm (default: 0.01)
hidden_dim [Optional] Hidden dimension size for the neural network (default: 64)
credible_threshold [Optional] Threshold for defining the credible set (e.g., 0.95 for a 95% credible set) (default: 0.95)

Parameter Adaptation: Adjust parameters based on tissue quality, species, and condition. Literature values take priority, then official defaults, then tissue-specific adjustments.

Proven Scripts

Scripts that have been successfully executed and passed analysis review. These are automatically saved after successful runs.

Species Tissue Condition Date Score
(none yet)

Common Issues

Error Cause Solution
(accumulated from runs)

References

  • Source: Biomni
  • Category: genomics
  • Language: Python

🗣️ 辩论机制(debate_analysis)

本 skill 在执行后,如果涉及参数选择、方法决策、结果判断等不确定环节,必须调用 工具进行多角色辩论。

辩论规则

  • 正方 3 位专业编辑(各自独立,互相看不到):生物学编辑 / 统计学编辑 / 生信编辑
  • 反方 4 位专业编辑(各自独立,互相看不到,也看不到正方):生物学编辑 / 统计学编辑 / 生信编辑 / 历史经验编辑
  • 裁判:看到所有 7 方论点后给出裁决 + 置信度(高/中/低)
  • 上下文隔离:每个编辑是独立的 LLM API 调用,messages 只包含自己的 prompt
  • 分科知识库:生物学编辑用 biology_kb / 统计学编辑用 statistics_kb / 生信编辑用 bioinfo_kb / 历史经验编辑用 history_errors
  • 辩论结果自动归档到 results/.../log/debate_*.json

Read the full file on GitHub · 129 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 129 lines · 40 tokens per session scan A c178af9099ff

Subscribe to this mod's changes

bayesian_finemapping_with_deep_vi is a skill published in the GitHub repository GGbond-bo/MemOmics-Agent (19 stars, last pushed 2d ago), licensed MIT. It adds 40 tokens to every session and 1,710 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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