boltz

boltz is a skill for Claude Code from GGbond-bo/MemOmics-Agent. It costs 53 tokens per session (1,409 once invoked), scanned A, a copy of boltz, MIT.

A structure-prediction tool for modelling complexes made from proteins, DNA, RNA, and small molecules. It uses Boltz-2 to produce molecular structure files and confidence measures for the predicted complex.

In plain words
What is it for?
Use it to predict protein, nucleic-acid, and ligand complexes from a YAML description, including designed binder–target complexes.
Why use it?
It helps assess whether a designed protein binder may fit and interact with its target before laboratory testing. Confidence measures help show how much to trust each prediction.

Skill for Claude Code

Written for Claude Code: when-to-use in frontmatter.

Good fit Use it to predict protein, nucleic-acid, and ligand complexes from a YAML description, including designed binder–target complexes.

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Install with agentmods
npx agentmods add skills/ggbond-bo/memomics-agent/boltz
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add GGbond-bo/MemOmics-Agent --skill boltz
Clone the repo
git clone --depth 1 https://github.com/GGbond-bo/MemOmics-Agent

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for boltz

README.md
[![agentmods](https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/boltz/github.svg)](https://agentmods.dev/skills/ggbond-bo/memomics-agent/boltz)
Your own site
<a href="https://agentmods.dev/skills/ggbond-bo/memomics-agent/boltz"><img src="https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/boltz/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for boltz

Your own site · 80×15
<a href="https://agentmods.dev/skills/ggbond-bo/memomics-agent/boltz"><img src="https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/boltz.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 53 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,409 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 89% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00053 $0.01409
Opus 5 $0.00026 $0.00705
Sonnet 5 $0.00011 $0.00282
Haiku 4.5 $0.00005 $0.00141

Measured 7d ago against content hash 62f342cc03b2, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

boltz scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 7d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

89% identical to boltz — 240 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

hermes_home/skills/bioinformatics/boltz/SKILL.md · 119 lines

How it starts

The opening of the file, as written. The whole thing — 119 lines — stays where its author put it; the contents beside it link to each section on GitHub.

📦 本 skill 由 OpenAI4S (PKU-YuanGroup, MIT/Apache-2.0) 移植。 原仓库: https://github.com/PKU-YuanGroup/OpenAI4S

Boltz-2

Boltz-2 is the open-weights diffusion co-folder closest in surface to AlphaFold3: a YAML describing protein, DNA, RNA, and ligand chains in, mmCIF plus pTM/ipTM/pLDDT confidences out, with an optional small-molecule affinity head. Among our four co-fold skills it is the default for binder-validation campaigns — fully open MIT weights and the fastest sampler; pick chai1 when you want a second independent model for consensus, openfold3 when AF3-faithful settings matter, and esmfold2 when you can live without an MSA. Code and weights are MIT (PyPI boltz, github.com/jwohlwend/boltz).

Running it

# complex.yaml
version: 1
sequences:
  - protein:
      id: A
      sequence: MVTPEGNVSLVDESLLVGVTDEDRAVRS...   # target
  - protein:
      id: B
      sequence: AIQRTPKIQVYSRHPAENG...            # binder
  - ligand:
      id: L
      smiles: 'N[C@@H](Cc1ccc(O)cc1)C(=O)O'      # or  ccd: SAH
boltz predict complex.yaml \
    --use_msa_server --out_dir out/ --recycling_steps 3 --diffusion_samples 5

Each protein chain needs an MSA; without one the run exits before the model loads. --use_msa_server queries api.colabfold.com (expect a 30–90 s pause per chain) and is the right default unless you already have an .a3m to name under msa: in the YAML. Setting msa: empty forces single-sequence mode — that is an accuracy sacrifice, not a speed or memory optimization, because the MSA search runs on CPU before the GPU stage starts.

Per input the output lands at out/boltz_results_complex/predictions/complex/. Read confidence_complex_model_0.json first: iptm > 0.5 is the community pass line for an interface, complex_plddt > 0.7 for the fold itself, and confidence_score is the weighted aggregate the structures are ranked by. Structures themselves are complex_model_{0..N-1}.cif (or .pdb with --output_format pdb).

Read the full file on GitHub · 119 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 7d ago First seen · 119 lines · 53 tokens per session scan A 62f342cc03b2

Subscribe to this mod's changes

boltz is a skill published in the GitHub repository GGbond-bo/MemOmics-Agent (19 stars, last pushed 8d ago), licensed MIT. It adds 53 tokens to every session and 1,409 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. It is 89% identical to boltz, differing in 240 lines, and is treated as a copy.

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