create_scvi_embeddings_scRNA

create_scvi_embeddings_scRNA is a skill for Claude Code from GGbond-bo/MemOmics-Agent. It costs 32 tokens per session (2,409 once invoked), scanned A, original, MIT.

A tool for creating scVI and scANVI embeddings from single-cell RNA sequencing data and saving them in an AnnData object. An embedding is a compact numerical representation that places similar cells near each other for later analysis.

In plain words
What is it for?
Use it to load an AnnData file, use its batch and cell-type information, create the embeddings, and save the updated data.
Why use it?
It provides a consistent way to prepare single-cell data for visualisation, clustering, or annotation while checking that the batch and cell-label columns are sensible.

Skill for Claude Code

Written for Claude Code: when-to-use in frontmatter.

Good fit Use it to load an AnnData file, use its batch and cell-type information, create the embeddings, and save the updated data.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add GGbond-bo/MemOmics-Agent --skill create_scvi_embeddings_scrna
Clone the repo
git clone --depth 1 https://github.com/GGbond-bo/MemOmics-Agent

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for create_scvi_embeddings_scRNA

README.md
[![agentmods](https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna/github.svg)](https://agentmods.dev/skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna)
Your own site
<a href="https://agentmods.dev/skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna"><img src="https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for create_scvi_embeddings_scRNA

Your own site · 80×15
<a href="https://agentmods.dev/skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna"><img src="https://agentmods.dev/badge/skills/ggbond-bo/memomics-agent/create_scvi_embeddings_scrna.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 32 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,409 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00032 $0.02409
Opus 5 $0.00016 $0.01205
Sonnet 5 $0.00006 $0.00482
Haiku 4.5 $0.00003 $0.00241

Measured 9d ago against content hash 8f052c889db9, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

create_scvi_embeddings_scRNA scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/run.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

hermes_home/skills/bioinformatics/create_scvi_embeddings_scRNA/SKILL.md · 193 lines

How it starts

The opening of the file, as written. The whole thing — 193 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Create Scvi Embeddings Scrna

Create scVI and scANVI embeddings for single-cell RNA-seq data, saving the results to an AnnData object.

When to Use

When you need create scvi embeddings scRNA analysis

Parameters

Parameter Default Notes
adata_filename [Required] Filename of the AnnData object to load (str)
batch_key [Required] Column name in adata.obs for batch information (str)
label_key [Required] Column name in adata.obs for cell type labels (str)
data_dir [Required] Directory path where the AnnData file is located and where output will be saved (str)

⚠️ batch_key 预检查(写代码前必须执行):使用 batch_key 前必须先用 adata.obs['<batch_key>'].nunique() 检查唯一条目数。若 >100 且 ≠ 预期样本数 → 阻断执行,提示用户可能误用了 barcode/cells 列。已有 sample_id (16,003 unique) 的前车之鉴。

Parameter Adaptation: Adjust parameters based on tissue quality, species, and condition. Literature values take priority, then official defaults, then tissue-specific adjustments.

Proven Scripts

Scripts that have been successfully executed and passed analysis review. These are automatically saved after successful runs.

Species Tissue Condition Date Score
(none yet)

Common Issues

Error Cause Solution
(accumulated from runs)

References

  • Source: Biomni
  • Category: genomics
  • Language: Python

📊 集成质量评估(必输出)

铁轨规则:scVI 嵌入后,必须运行 4 项评估并输出图表。未输出 → rail_review(post) 阻断。

必输出指标(4 项铁轨)

# 指标 通过 警告 阻断
1 LISI > N_batch×0.8 0.5-0.8 < 0.5
2 ASW(batch) < 0.1 0.1-0.15 > 0.15
3 kBET rejection < 0.05 0.05-0.15 > 0.15
4 ELBO 收敛 loss 平稳 loss 波动 < 10% loss 未收敛

scVI 额外检查

  • latent 维度adata.obsm['X_scVI'].shape[1] ≤ 30,过大 → 过拟合
  • 重构误差:NMSE 应在 0.1-0.5

Read the full file on GitHub · 193 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 193 lines · 32 tokens per session scan A 8f052c889db9

Subscribe to this mod's changes

create_scvi_embeddings_scRNA is a skill published in the GitHub repository GGbond-bo/MemOmics-Agent (19 stars, last pushed 2d ago), licensed MIT. It adds 32 tokens to every session and 2,409 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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