dbsnp-database

dbsnp-database is a skill for Claude Code, Codex from google-deepmind/science-skills. It costs 84 tokens per session (3,688 once invoked), scanned A, original, Apache-2.0.

A lookup tool for dbSNP, the U.S. National Institutes of Health database of short DNA changes such as SNPs and indels. It connects rsIDs, genomic coordinates, and HGVS variant descriptions.

In plain words
What is it for?
Use it to find a variant by rsID, genomic position, or HGVS string; convert between these formats; and inspect its type, gene links, clinical information, and population frequencies.
Why use it?
It removes the need to search several variant formats and databases by hand. It can also return related genes, clinical significance, allele frequencies, and coordinates.

Skill for Claude CodeCodex

About the project

Science Skills is a collection of add-ons that give AI agents structured instructions, scripts, and references for scientific research, including genomics, structural biology, cheminformatics, and literature search. Researchers use it to guide agents through specialized scientific tasks with information from databases and tools such as AlphaGenome, AFDB, and UniProt. The catalogue entries are individual skills from this collection.

google-deepmind/science-skills · 2,835 stars · on GitHub · antigravity.google

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/google-deepmind/science-skills/dbsnp_database
Any agent
npx skills add google-deepmind/science-skills --skill dbsnp_database
Clone the repo
git clone --depth 1 https://github.com/google-deepmind/science-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for dbsnp-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/google-deepmind/science-skills/dbsnp_database.svg)](https://agentmods.dev/skills/google-deepmind/science-skills/dbsnp_database)
Your own site
<a href="https://agentmods.dev/skills/google-deepmind/science-skills/dbsnp_database"><img src="https://agentmods.dev/badge/skills/google-deepmind/science-skills/dbsnp_database.svg" alt="Measured on agentmods" height="20"></a>
Per session 84 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,688 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00084 $0.03688
Opus 5 $0.00042 $0.01844
Sonnet 5 $0.00017 $0.00738
Haiku 4.5 $0.00008 $0.00369

Measured 6d ago against content hash 261817ea3ca4, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-05, from the pricing page.

Security

Grade A, and why

dbsnp-database scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/dbsnp_cli.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

HTTP or curl requests. The script automatically handles rate limiting,
skills/dbsnp_database/SKILL.md · 351 lines

How it starts

The opening of the file, as written. The whole thing — 351 lines — stays where its author put it; the contents beside it link to each section on GitHub.

dbSNP Database Integration

Prerequisites

  1. uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
  2. User Notification: If .licenses/dbsnp_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://www.ncbi.nlm.nih.gov/snp/, then (2) create the file recording the notification text and timestamp.
  3. .env file: Make sure the .env file exists in your home directory. Create one if it does not exist.
  4. NCBI_API_KEY (optional): Raises the NCBI rate limit from 3 to 10 requests/second. The skill works without it, but a key is recommended if the user plans many queries or encounters a 429 error. You can register for a key for free at https://www.ncbi.nlm.nih.gov/account/settings/. You MUST use the safe credentials protocol in the credentials skill to check for and request this key if this skill looks relevant to the user's request.

Core Rules

  • Use the Wrapper: ALWAYS execute the provided wrapper script scripts/dbsnp_cli.py to query the database rather than constructing custom HTTP or curl requests. The script automatically handles rate limiting, retries, and JSON parsing.
  • Command Choice: Do NOT use search-region to find the rsID of a specific variant; use resolve-variant instead.
  • Output Size: Avoid using --full on get-variant unless specifically needed, as raw payloads can exceed 1 MB.
  • Shell Safety: Always wrap HGVS strings in single quotes to prevent shell expansion errors.
  • Notification: If this skill is used, ensure this is mentioned in the output.

When to Use

Use this skill when you need to:

  • Map a genomic variant to its canonical rsID (from VCF coordinates or HGVS notation).
  • Retrieve summary data for an rsID: variant type, gene associations, clinical significance, and population allele frequencies.
  • Convert an rsID back to genomic coordinates on a specific assembly.
  • Find all known variants within a chromosomal region.

Read the full file on GitHub · 351 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 351 lines · 84 tokens per session scan A 261817ea3ca4

Subscribe to this mod's changes

dbsnp-database is a skill published in the GitHub repository google-deepmind/science-skills (2,835 stars, last pushed 2mo ago), licensed Apache-2.0. It adds 84 tokens to every session and 3,688 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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