gtex-database

gtex-database is a skill for Claude Code, Codex from google-deepmind/science-skills. It costs 43 tokens per session (1,647 once invoked), scanned A, original, Apache-2.0.

A data tool for the GTEx Project, a research project that records how active genes are in different human tissues and how genetic variants affect that activity. It provides RNA expression measurements and eQTL data, which links DNA variants to gene activity.

In plain words
What is it for?
Use it to identify a gene, find where it is most active, retrieve its typical expression levels by tissue, or find significant variant–gene activity links in a tissue or genomic region.
Why use it?
It helps you compare gene activity across 54 non-diseased tissue types and investigate whether variants influence a gene's activity. This avoids collecting and comparing these measurements manually.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

About the project

Science Skills is a collection of add-ons that give AI agents structured instructions, scripts, and references for scientific research, including genomics, structural biology, cheminformatics, and literature search. Researchers use it to guide agents through specialized scientific tasks with information from databases and tools such as AlphaGenome, AFDB, and UniProt. The catalogue entries are individual skills from this collection.

google-deepmind/science-skills · 2,835 stars · on GitHub · antigravity.google

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/google-deepmind/science-skills/gtex_database
Any agent
npx skills add google-deepmind/science-skills --skill gtex_database
Clone the repo
git clone --depth 1 https://github.com/google-deepmind/science-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for gtex-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/google-deepmind/science-skills/gtex_database.svg)](https://agentmods.dev/skills/google-deepmind/science-skills/gtex_database)
Your own site
<a href="https://agentmods.dev/skills/google-deepmind/science-skills/gtex_database"><img src="https://agentmods.dev/badge/skills/google-deepmind/science-skills/gtex_database.svg" alt="Measured on agentmods" height="20"></a>
Per session 43 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,647 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00043 $0.01647
Opus 5 $0.00022 $0.00823
Sonnet 5 $0.00009 $0.00329
Haiku 4.5 $0.00004 $0.00165

Measured 6d ago against content hash bbd4c8ac358d, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-06, from the pricing page.

Security

Grade A, and why

gtex-database scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/gtex_cli.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/gtex_database/SKILL.md · 177 lines

How it starts

The opening of the file, as written. The whole thing — 177 lines — stays where its author put it; the contents beside it link to each section on GitHub.

GTEx Database Integration

This skill retrieves transcriptomics data (RNA expression baselines) and expression Quantitative Trait Loci (eQTLs) from the GTEx Portal API V2. It provides access to median TPM (Transcripts Per Million) values for genes and significant eQTLs for variants across 54 human tissue sites.

Prerequisites

  1. uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
  2. User Notification: If .licenses/gtex_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://gtexportal.org/home/license and https://gtexportal.org/home/documentationPage#gtexApi, then (2) create the file recording the notification text and timestamp.

When to Use

Use this skill when you need to:

  • Map a gene symbol to its Versioned GENCODE ID.
  • Retrieve the baseline median expression level (in TPM) of a gene across various tissues.
  • Find the top tissues where a particular gene is most highly expressed.
  • Fetch significant single-tissue eQTLs for a variant or within a chromosomal window.
  • Get all significant eQTLs associated with a specific gene.
  • Contextualise a variant within GWAS loci using eQTL data.

Do NOT use when you need to:

  • Query for protein-level expression or post-translational modifications (PTMs). GTEx only measures mRNA abundance.
  • Query gene expression in diseased tissues (e.g., tumor samples, cirrhosis). GTEx is a baseline atlas of normal, non-diseased tissues.
  • Query embryonic or fetal gene expression. GTEx donors are adults only.

Core Rules

CRITICAL: You MUST respect GTEx Portal API Terms of Use.

  • Use the Wrapper: ALWAYS execute the provided helper scripts to query the database rather than accessing the database directly. The scripts automatically enforce the required rate limit gracefully.
  • Limit requests to maximum 250 items per page where applicable.
  • Notification: If this skill is used, ensure this is mentioned in the output.

Read the full file on GitHub · 177 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 177 lines · 43 tokens per session scan A bbd4c8ac358d

Subscribe to this mod's changes

gtex-database is a skill published in the GitHub repository google-deepmind/science-skills (2,835 stars, last pushed 2mo ago), licensed Apache-2.0. It adds 43 tokens to every session and 1,647 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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