opentargets-database

opentargets-database is a skill for Claude Code, Codex from google-deepmind/science-skills. It costs 40 tokens per session (2,404 once invoked), scanned A, original, Apache-2.0.

A tool for querying Open Targets, a research database that connects genes and biological targets with diseases, medicines, genetics, and other evidence.

In plain words
What is it for?
Use it to investigate possible treatment targets, compare target-disease links, review genetic or experimental evidence, and check known drugs, safety, and drug-development potential.
Why use it?
It brings several kinds of biomedical evidence together instead of requiring separate searches across research sources.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

About the project

Science Skills is a collection of add-ons that give AI agents structured instructions, scripts, and references for scientific research, including genomics, structural biology, cheminformatics, and literature search. Researchers use it to guide agents through specialized scientific tasks with information from databases and tools such as AlphaGenome, AFDB, and UniProt. The catalogue entries are individual skills from this collection.

google-deepmind/science-skills · 2,845 stars · on GitHub · antigravity.google

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/google-deepmind/science-skills/opentargets_database
Any agent
npx skills add google-deepmind/science-skills --skill opentargets_database
Clone the repo
git clone --depth 1 https://github.com/google-deepmind/science-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for opentargets-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/google-deepmind/science-skills/opentargets_database.svg)](https://agentmods.dev/skills/google-deepmind/science-skills/opentargets_database)
Your own site
<a href="https://agentmods.dev/skills/google-deepmind/science-skills/opentargets_database"><img src="https://agentmods.dev/badge/skills/google-deepmind/science-skills/opentargets_database.svg" alt="Measured on agentmods" height="20"></a>
Per session 40 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,404 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00040 $0.02404
Opus 5 $0.00020 $0.01202
Sonnet 5 $0.00008 $0.00481
Haiku 4.5 $0.00004 $0.00240

Measured 7d ago against content hash 06f42275cb2a, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-06, from the pricing page.

Security

Grade A, and why

opentargets-database scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 7d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/query_opentargets.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

automatically truncates overly large responses. NEVER write your own curl or
skills/opentargets_database/SKILL.md · 204 lines

How it starts

The opening of the file, as written. The whole thing — 204 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Open Targets Database Skill

Overview

This skill provides access to the Open Targets Platform GraphQL API. It aggregates multi-modal evidence from genetics (GWAS/eQTL), pathways, animal models, and clinical trials to rank target-disease associations and identify druggable genes.

Prerequisites

  1. uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
  2. User Notification: If .licenses/opentargets_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://platform-docs.opentargets.org/licence, then (2) create the file recording the notification text and timestamp.

Core Rules

  • Use the Wrapper: ALWAYS execute the provided helper scripts to query the database rather than accessing the database directly. The scripts automatically enforce fair use and implement retry logic.
  • Output Flag: The --output flag is always required as output can be very large. Use jq or write your own code to process this JSON file.
  • Notification: If this skill is used, ensure this is mentioned in the output.

Quick Reference

Always use the provided Python script scripts/query_opentargets.py to quickly query the database. It handles API communication, retries, formatting, and automatically truncates overly large responses. NEVER write your own curl or similar requests.

Usage:

uv run scripts/query_opentargets.py --output /tmp/opentargets_results.json [OPTIONS] COMMAND [ARGS]...

Common Options:

  • --output PATH: Required. Path to write the JSON output file.
  • --limit N: Limit the number of items returned in arrays (default is 50). Use a smaller number like 10 when doing preliminary exploration.
  • --page-size N: Set the API pagination size (default is 200). Increase if you need more results (e.g., a study with many credible sets).

Available Commands:

Read the full file on GitHub · 204 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 7d ago First seen · 204 lines · 40 tokens per session scan A 06f42275cb2a

Subscribe to this mod's changes

opentargets-database is a skill published in the GitHub repository google-deepmind/science-skills (2,845 stars, last pushed 2mo ago), licensed Apache-2.0. It adds 40 tokens to every session and 2,404 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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