molclaw-karmadock-tool

molclaw-karmadock-tool is a skill for Claude Code, Codex from InternScience/MolClaw. It costs 26 tokens per session (1,122 once invoked), scanned A, original, MIT.

A virtual-screening tool for drug discovery that ranks how small molecules, called ligands, may fit with a protein. It can generate docking poses, which are predicted molecule positions, and summary measurements from SMILES, PDB, and MOL2 files.

In plain words
What is it for?
Use it to run batch protein–ligand screening, rank candidates, export selected poses, validate inputs, and produce tracked output files.
Why use it?
It helps compare many candidate molecules and identify the ones most worth examining further, instead of inspecting each one manually.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to run batch protein–ligand screening, rank candidates, export selected poses, validate inputs, and produce tracked output files.

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Install with agentmods
npx agentmods add skills/internscience/molclaw/molclaw-karmadock-tool
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add InternScience/MolClaw --skill molclaw-karmadock-tool
Clone the repo
git clone --depth 1 https://github.com/InternScience/MolClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for molclaw-karmadock-tool

README.md
[![agentmods](https://agentmods.dev/badge/skills/internscience/molclaw/molclaw-karmadock-tool/github.svg)](https://agentmods.dev/skills/internscience/molclaw/molclaw-karmadock-tool)
Your own site
<a href="https://agentmods.dev/skills/internscience/molclaw/molclaw-karmadock-tool"><img src="https://agentmods.dev/badge/skills/internscience/molclaw/molclaw-karmadock-tool/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

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Your own site · 80×15
<a href="https://agentmods.dev/skills/internscience/molclaw/molclaw-karmadock-tool"><img src="https://agentmods.dev/badge/skills/internscience/molclaw/molclaw-karmadock-tool.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 26 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,122 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00026 $0.01122
Opus 5 $0.00013 $0.00561
Sonnet 5 $0.00005 $0.00224
Haiku 4.5 $0.00003 $0.00112

Measured 8d ago against content hash 999bba002448, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

molclaw-karmadock-tool scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/L1_tools/molclaw-karmadock-tool/SKILL.md · 112 lines

How it starts

The opening of the file, as written. The whole thing — 112 lines — stays where its author put it; the contents beside it link to each section on GitHub.

KarmaDock Virtual Screening

Note:

  • Local files are not directly accessible by the server. Please upload them to the server using molclaw-file-transfer before execution.
  • For PDB file inputs, it is recommended to preprocess them using molclaw-pdbfixer before execution.
  • Please refer to skill molclaw-scp-server to complete tool invocation.

Usage

1. KarmaDock Virtual Screening

The description of tool karmadock_tool.

Performs protein-ligand virtual screening with KarmaDock for batch ranking and optional pose export workflows.
Args:
    ligand_smi (str): Ligand SMILES input file path, required.
    protein_file (str): Protein PDB file path, required.
    crystal_ligand_file (str): Crystal ligand MOL2 file for pocket localization, required.
    score_threshold (float): Score threshold used for pose export mask, default 70.0.
    batch_size (int): Inference batch size, default 64.
    random_seed (int): Random seed for reproducibility, default 2020.
    dry_run (bool): Validate inputs and create tracked output directory without execution, default False.
Return:
    status (str): success, partial_success, or error execution status.
    msg (str): Human-readable execution summary.
    output_dir (str): Run-specific directory under tool_result/karmadock_tool_result.
    ligand_smi (str): Resolved ligand SMILES file absolute path.
    protein_file (str): Resolved protein PDB file absolute path.
    crystal_ligand_file (str): Resolved crystal ligand MOL2 absolute path.
    score_threshold (float): Effective score threshold used in this run.
    batch_size (int): Effective batch size used.
    random_seed (int): Effective random seed used.
    out_init (bool): Always True in wrapper.
    out_uncorrected (bool): Always True in wrapper.
    out_corrected (bool): Always True in wrapper.
    dry_run (bool): Effective dry-run flag.
    return_code (int | None): Delegated process return code.
    pose_export_hint (str | None): Diagnostic message when SDF export is requested but missing.
    key_files (dict): Key output files including score_csv and pose_sdf_files.
    metrics (dict): Summary metrics including num_ligands_scored and karma score extrema.

Read the full file on GitHub · 112 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 112 lines · 26 tokens per session scan A 999bba002448

Subscribe to this mod's changes

molclaw-karmadock-tool is a skill published in the GitHub repository InternScience/MolClaw (33 stars, last pushed 1mo ago), licensed MIT. It adds 26 tokens to every session and 1,122 once invoked, about $0.0001 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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