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esmfold2

esmfold2 is a skill for Claude Code, Codex from JimLiu/science-skills. It costs 223 tokens per session (3,099 once invoked), scanned A, original, no licence file.

A structure-prediction tool for folding proteins, DNA, RNA, and small molecules together. It supports single sequences, multiple-sequence alignments, ligands described by chemical formats, and modified residues.

In plain words
What is it for?
Use it to predict protein or nucleic-acid structures, model antibody-antigen or other complexes, and study protein-ligand interactions.
Why use it?
It helps estimate the three-dimensional shape of biological molecules and how they may fit together when experimental structures are unavailable.

Skill for Claude CodeCodex

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

not rated 229repo +1 8d ago A scan 223 tokens no licence

Good fit Use it to predict protein or nucleic-acid structures, model antibody-antigen or other complexes, and study protein-ligand interactions.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/jimliu/science-skills/esmfold2
View source ↗ JimLiu/science-skills
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add JimLiu/science-skills --skill esmfold2
Clone the repo
git clone --depth 1 https://github.com/JimLiu/science-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for esmfold2

README.md
[![agentmods](https://agentmods.dev/badge/skills/jimliu/science-skills/esmfold2/github.svg)](https://agentmods.dev/skills/jimliu/science-skills/esmfold2)
Your own site
<a href="https://agentmods.dev/skills/jimliu/science-skills/esmfold2"><img src="https://agentmods.dev/badge/skills/jimliu/science-skills/esmfold2/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for esmfold2

Your own site · 80×15
<a href="https://agentmods.dev/skills/jimliu/science-skills/esmfold2"><img src="https://agentmods.dev/badge/skills/jimliu/science-skills/esmfold2.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 223 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,099 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00223 $0.03099
Opus 5.5 $0.00089 $0.01240
Sonnet 5.5 $0.00045 $0.00620
Haiku 4.5 $0.00022 $0.00310

Measured 2mo ago against content hash 28e625bab51a, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

esmfold2 scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2mo ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/esmfold2/SKILL.md · 229 lines

The source is not reproduced here

No licence file

A repository with no LICENSE is all rights reserved by default, so the body is not copied here. The metadata, the measurements and the link are.

Read it on GitHub

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2mo ago First seen · 229 lines · 223 tokens per session scan A 28e625bab51a

Subscribe to this mod's changes

esmfold2 is a skill published in the GitHub repository JimLiu/science-skills (229 stars, last pushed 8d ago), with no licence file. It adds 223 tokens to every session and 3,099 once invoked, about $0.0009 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Scientificbiomodels
Related

esmfold2 compared with skills from other repositories

esmfold2 next to 6 skills from other repositories
ModTypeStarsLast pushLicenceScanTokensWorks with
esmfold2JimLiu/science-skillsSkill2298d agononeA223Claude Code, Codex
esmfold2aipoch/open-scienceSkill5.5kyesterdayApache-2.0A223Claude Code, Codex
openfold3aipoch/open-scienceSkill5.5kyesterdayApache-2.0A60Claude Code, Codex
ligandmpnnaipoch/open-scienceSkill5.5kyesterdayApache-2.0A100Claude Code, Codex
alphafold2aipoch/open-scienceSkill5.5kyesterdayApache-2.0A117Claude Code, Codex
boltzaipoch/open-scienceSkill5.5kyesterdayApache-2.0A88Claude Code, Codex
chai1aipoch/open-scienceSkill5.5kyesterdayApache-2.0A98Claude Code, Codex