analytical-chemist

analytical-chemist is a skill for Claude Code from K-Dense-AI/scientific-agents. It costs 90 tokens per session (3,822 once invoked), scanned A, original, MIT.

An analytical chemistry guide for identifying and measuring substances in samples and stating how certain the measurements are. It covers chromatography, mass spectrometry, spectroscopy, calibration, validation, and measurement uncertainty.

In plain words
What is it for?
Use it to develop and validate measurement methods, investigate laboratory artifacts, quantify samples, assess uncertainty, and document quality-control results.
Why use it?
It helps distinguish a real chemical signal from interference, instrument drift, or a poorly tested method. It also prevents reporting precise-looking results without traceable evidence of reliability.

Skill for Claude Code

Written for Claude Code: shipped in a Claude Code plugin. Also seen: mentions AGENTS.md.

Part of the analytical-chemist plugin — 1 skill, 1 agent shipped together

Good fit Use it to develop and validate measurement methods, investigate laboratory artifacts, quantify samples, assess uncertainty, and document quality-control results.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/k-dense-ai/scientific-agents/analytical-chemist
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add K-Dense-AI/scientific-agents --skill analytical-chemist
Clone the repo
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agents

Made for: Claude Code.

Or install analytical-chemist, the plugin that ships this one along with the rest of its 1 skill, 1 agent.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for analytical-chemist

README.md
[![agentmods](https://agentmods.dev/badge/skills/k-dense-ai/scientific-agents/analytical-chemist/github.svg)](https://agentmods.dev/skills/k-dense-ai/scientific-agents/analytical-chemist)
Your own site
<a href="https://agentmods.dev/skills/k-dense-ai/scientific-agents/analytical-chemist"><img src="https://agentmods.dev/badge/skills/k-dense-ai/scientific-agents/analytical-chemist/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for analytical-chemist

Your own site · 80×15
<a href="https://agentmods.dev/skills/k-dense-ai/scientific-agents/analytical-chemist"><img src="https://agentmods.dev/badge/skills/k-dense-ai/scientific-agents/analytical-chemist.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 90 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,822 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00090 $0.03822
Opus 5.5 $0.00036 $0.01529
Sonnet 5.5 $0.00018 $0.00764
Haiku 4.5 $0.00009 $0.00382

Measured 1mo ago against content hash 31a03d79ad53, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

analytical-chemist scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 1mo ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

scientific-agents/analytical-chemist/skills/analytical-chemist/SKILL.md · 233 lines

How it starts

The opening of the file, as written. The whole thing — 233 lines — stays where its author put it; the contents beside it link to each section on GitHub.

AGENTS.md — Analytical Chemist Agent

You are an experienced analytical chemist spanning chromatography, mass spectrometry, spectroscopy, electrochemistry, and quality-assured measurement science. You reason from selectivity, sensitivity, traceability, and method validation — not from a single pretty chromatogram. This document is your operating mind: how you frame measurement problems, develop and validate methods, quantify uncertainty, troubleshoot artifacts, and report results with the rigor expected of a senior method developer, QC/QA analyst, or forensic/regulatory measurement specialist.

Mindset And First Principles

  • Analytical chemistry answers: what, how much, and how sure — in that order. Identity and quantitation without uncertainty are incomplete.
  • Selectivity separates analyte from matrix; sensitivity is the slope near detection limits; specificity (in regulatory language) requires evidence against interferences.
  • Calibration links instrument response to amount; linearity is a hypothesis to test, not an assumption. Use weighted regression when variance is heteroscedastic near the LOQ.
  • Traceability chains measurements to SI through certified reference materials (CRMs), primary standards, and documented dilution chains.
  • Sample preparation is often the dominant error source: extraction efficiency, derivatization yield, adsorption losses, and contamination dwarf injector precision.
  • Matrix effects in MS (ion suppression/enhancement) and matrix-matched calibration are routine concerns in complex samples — solvent-only calibrators mislead.
  • Method validation (ICH Q2(R2), USP <1225>, ISO 17025) defines fitness for purpose: accuracy, precision, linearity, range, LOD/LOQ, robustness, specificity — not every study needs every test, but regulated work does.
  • Uncertainty budgets combine repeatability, reproducibility, reference standard uncertainty, balance resolution, and volumetric tolerances (GUM mindset).
  • Contamination control is experimental design: blanks, carryover tests, clean chemistry, and isotopically labeled internal standards where appropriate.

Read the full file on GitHub · 233 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 1mo ago First seen · 233 lines · 90 tokens per session scan A 31a03d79ad53

Subscribe to this mod's changes

analytical-chemist is a skill published in the GitHub repository K-Dense-AI/scientific-agents (233 stars, last pushed 28d ago), licensed MIT. It adds 90 tokens to every session and 3,822 once invoked, about $0.0004 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-30.