Query the CADEC (CSIRO Adverse Drug Event Corpus). Use whenever the user asks about adverse drug event mentions in consumer health text, entity annotations from patient forum posts, MedDRA/SNOMED-CT normalised ADR spans, or wants to look up drugs, symptoms, or coded entities in the CADEC corpus.
The DDI Corpus 2013 is the standard benchmark for drug-drug interaction (DDI) extraction from biomedical text. Each XML file contains sentences with annotated drug entities and pairwise DDI labels.
Query drug/chemical and gene/protein entities in the BioCreative VII DrugProt dataset. Returns annotated relations (e.g., INHIBITOR, ACTIVATOR, SUBSTRATE) between chemicals and genes/proteins from biomedical literature.
Query the PHEE pharmacovigilance event extraction dataset. Use whenever the user asks about annotated adverse drug events, pharmacovigilance case reports, drug–effect associations from medical literature, or wants to find PHEE examples mentioning a drug name, adverse effect, or condition.
Query the PsyTAR psychiatric adverse-reaction corpus. Use when the user asks about patient-reported ADRs, withdrawal symptoms, drug indications, or effectiveness for Zoloft, Lexapro, Cymbalta, or Effexor XR. Accepts drug names (brand or generic), symptom terms, or UMLS CUIs.
Query TAC 2017 ADR annotated drug labels for adverse drug reactions. Use whenever the user asks about ADRs extracted from FDA drug labels, MedDRA-normalized adverse reactions, or wants to look up a drug name, ADR string, or MedDRA code in the TAC 2017 ADR corpus.
Query the WHO ATC/DDD Classification System. Use whenever the user asks about ATC codes, drug classification hierarchy, Defined Daily Doses (DDD), or wants to look up drugs by ATC class or find the ATC code for a drug name.
Query the ChEBI (Chemical Entities of Biological Interest) database. Use whenever the user asks about small molecule identifiers, chemical ontology roles, molecular formulae, SMILES, InChI, synonyms, or cross-references for biologically relevant chemical compounds via ChEBI.
Query NDF-RT (National Drug File Reference Terminology) via the NCI EVS REST API. Use when looking up drug mechanisms of action, physiological effects, pharmacologic classes, chemical structures, or drug–disease relationships (maytreat / mayprevent) in NDF-RT. Accepts drug names or NDF-RT codes.
Query the RxNorm drug naming and normalization API. Use whenever the user asks to look up an RxCUI, normalize a drug name, find drug interactions, retrieve brand/trade names, or resolve any clinical drug name via RxNorm. Supports single drug or batch queries. Trigger on mentions of RxNorm, RxCUI, drug normalization…
Query the DRKG (Drug Repurposing Knowledge Graph). Use whenever the user asks about drug–gene, drug–disease, gene–disease, or other biomedical entity relationships in a knowledge-graph context, drug repurposing candidates, COVID-19 drug repurposing, or wants to explore neighbours of any biomedical entity (compound…
Query the DrugRepoBank drug repurposing evidence database. Use whenever the user asks about repurposing candidates, drug–disease–target repurposing evidence, or wants to look up any entity (drug name, DrugBank ID, ChEMBL ID, PubChem CID, TTD target ID, UniProt ID, disease name) in DrugRepoBank.
Query the OREGANO knowledge graph for computational drug repurposing. Use whenever the user asks about drug–target–disease–gene–pathway relationships, compound cross-references, drug repurposing hypotheses, or wants to explore neighbors of any biomedical entity in a knowledge graph that includes natural compounds.
Query the RepoDB drug repurposing database. Use whenever the user asks about drug-disease associations, drug repurposing candidates, or wants to look up any entity (drug name, indication, DrugBank ID, UMLS CUI, NCT ID) in RepoDB.
Query the RepurposeDrugs single-agent drug repurposing database. Use whenever the user asks about drug-disease repurposing associations, clinical trial phases for repurposed drugs, or wants to look up any entity (drug name, disease name, NCT ID) in RepurposeDrugs.
Query the Broad Institute Drug Repurposing Hub (6,800 compounds). Look up drugs by name, gene target, MOA, disease area, Broad ID, or InChIKey. Returns clinical phase, mechanism of action, targets, disease area, indication, and chemical identifiers.
Query the DrugLib.com Drug Review Dataset (UCI #461). Use whenever the user asks about patient drug reviews, drug effectiveness ratings, side-effect profiles, or condition-specific treatment experiences from DrugLib.com.
Query the WebMD Drug Reviews dataset (362 k patient reviews, 2007–2020). Use whenever the user asks about patient-reported drug effectiveness, ease of use, satisfaction ratings, side effects, or reviews for a specific drug or medical condition.
Query the DILIrank/FDA Liver Toxicity Knowledge Base (LTKB). Use whenever the user asks about drug-induced liver injury (DILI) risk, hepatotoxicity classification, or wants to look up any drug (by name, LTKB ID, or DILIst ID) in the DILIrank or DILIst datasets.
Query the UniTox drug toxicity database. Use whenever the user asks about organ-system toxicity ratings for a drug, multi-organ toxicity profiles, or wants to look up any entity (drug name, SMILES, SPLID) in UniTox.
Query the BindingDB drug-target binding affinity database. Use whenever the user asks about protein-ligand binding data, affinity measurements (Ki, IC50, Kd, EC50), or wants to look up binding partners for a UniProt ID, PDB ID, or compound SMILES string.
Query the ChEMBL database for drug molecules, bioactivity data, and drug targets via the ChEMBL REST API. Use whenever the user asks about drug properties (molecular weight, logP, Lipinski violations), drug-target interactions, bioactivity assay results, or wants to look up any entity by ChEMBL ID or drug/gene name in…
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