ena-database

ena-database is a skill for Claude Code, Codex from synthetic-sciences/openscience. It costs 43 tokens per session (1,561 once invoked), scanned A, original, Apache-2.0.

A programming guide to the European Nucleotide Archive, a public repository of DNA and RNA sequences and sequencing data. It helps retrieve raw reads, genome assemblies, annotations, and study information through APIs and file transfer.

In plain words
What is it for?
Use it to find studies, samples, or assemblies, download FASTQ files and genome assemblies, query organism information, and feed archived data into bioinformatics pipelines.
Why use it?
It removes the need to manually locate and download sequence datasets from different archive pages and formats.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

About the project

synthetic-sciences/openscience is an AI workbench that carries out scientific research by reading papers, forming hypotheses, writing and running code, conducting experiments, analyzing results, and preparing reports. Researchers use it for work in machine learning, biology, physics, and chemistry with remote or local models. Catalogue add-ons extend its scientific workflows through skills and instructions.

synthetic-sciences/openscience · 3,491 stars · on GitHub · openscience.sh

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/synthetic-sciences/openscience/ena-database
Any agent
npx skills add synthetic-sciences/openscience --skill ena-database
Clone the repo
git clone --depth 1 https://github.com/synthetic-sciences/openscience

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for ena-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/synthetic-sciences/openscience/ena-database.svg)](https://agentmods.dev/skills/synthetic-sciences/openscience/ena-database)
Your own site
<a href="https://agentmods.dev/skills/synthetic-sciences/openscience/ena-database"><img src="https://agentmods.dev/badge/skills/synthetic-sciences/openscience/ena-database.svg" alt="Measured on agentmods" height="20"></a>
Per session 43 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,561 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. Scan, not verified.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00043 $0.01561
Opus 5 $0.00022 $0.00781
Sonnet 5 $0.00009 $0.00312
Haiku 4.5 $0.00004 $0.00156

Measured 2d ago against content hash 289060fe4901, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-06, from the pricing page.

Security

Grade A, and why

ena-database scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

response = requests.get(base_url, params=params)
Origin

Copies of this mod

8 near-identical copies found in the catalogue:

backend/cli/skills/databases/ena-database/SKILL.md · 204 lines

How it starts

The opening of the file, as written. The whole thing — 204 lines — stays where its author put it; the contents beside it link to each section on GitHub.

ENA Database

Overview

The European Nucleotide Archive (ENA) is a comprehensive public repository for nucleotide sequence data and associated metadata. Access and query DNA/RNA sequences, raw reads, genome assemblies, and functional annotations through REST APIs and FTP for genomics and bioinformatics pipelines.

When to Use This Skill

This skill should be used when:

  • Retrieving nucleotide sequences or raw sequencing reads by accession
  • Searching for samples, studies, or assemblies by metadata criteria
  • Downloading FASTQ files or genome assemblies for analysis
  • Querying taxonomic information for organisms
  • Accessing sequence annotations and functional data
  • Integrating ENA data into bioinformatics pipelines
  • Performing cross-reference searches to related databases
  • Bulk downloading datasets via FTP or Aspera

Core Capabilities

1. Data Types and Structure

ENA organizes data into hierarchical object types:

Studies/Projects - Group related data and control release dates. Studies are the primary unit for citing archived data.

Samples - Represent units of biomaterial from which sequencing libraries were produced. Samples must be registered before submitting most data types.

Raw Reads - Consist of:

  • Experiments: Metadata about sequencing methods, library preparation, and instrument details
  • Runs: References to data files containing raw sequencing reads from a single sequencing run

Assemblies - Genome, transcriptome, metagenome, or metatranscriptome assemblies at various completion levels.

Sequences - Assembled and annotated sequences stored in the EMBL Nucleotide Sequence Database, including coding/non-coding regions and functional annotations.

Analyses - Results from computational analyses of sequence data.

Taxonomy Records - Taxonomic information including lineage and rank.

2. Programmatic Access

ENA provides multiple REST APIs for data access. Consult references/api_reference.md for detailed endpoint documentation.

Read the full file on GitHub · 204 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2d ago First seen · 204 lines · 43 tokens per session scan A 289060fe4901

Subscribe to this mod's changes

ena-database is a skill published in the GitHub repository synthetic-sciences/openscience (3,491 stars, last pushed today), licensed Apache-2.0. It adds 43 tokens to every session and 1,561 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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