genomic-intelligence

genomic-intelligence is a skill for Claude Code, Codex from synthetic-sciences/openscience. It costs 150 tokens per session (5,589 once invoked), scanned A, original, Apache-2.0.

A hosted DNA-sequence analysis service that uses machine-learning models to predict biological features. It accepts a gene, genomic region, or DNA/FASTA sequence and returns predictions through a web API, so models and GPUs run remotely.

In plain words
What is it for?
Use it to predict promoters, splice sites, enhancer activity, chromatin state, expression, or gene and transcript annotations from DNA sequence.
Why use it?
It avoids installing large models or providing a local GPU for these analyses. The structured results make it easier to use sequence predictions in automated workflows.

Skill for Claude CodeCodex

Which agent this was written for is unclear — built for openclaw. Also seen: built for openclaw.

Good fit Use it to predict promoters, splice sites, enhancer activity, chromatin state, expression, or gene and transcript annotations from DNA sequence.

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Install with agentmods
npx agentmods add skills/synthetic-sciences/openscience/genomic-intelligence
About the project

synthetic-sciences/openscience is an AI workbench that carries out scientific research by reading papers, forming hypotheses, writing and running code, conducting experiments, analyzing results, and preparing reports. Researchers use it for work in machine learning, biology, physics, and chemistry with remote or local models. Catalogue add-ons extend its scientific workflows through skills and instructions.

synthetic-sciences/openscience · 4,004 stars · on GitHub · openscience.sh

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add synthetic-sciences/openscience --skill genomic-intelligence
Clone the repo
git clone --depth 1 https://github.com/synthetic-sciences/openscience

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for genomic-intelligence

README.md
[![agentmods](https://agentmods.dev/badge/skills/synthetic-sciences/openscience/genomic-intelligence/github.svg)](https://agentmods.dev/skills/synthetic-sciences/openscience/genomic-intelligence)
Your own site
<a href="https://agentmods.dev/skills/synthetic-sciences/openscience/genomic-intelligence"><img src="https://agentmods.dev/badge/skills/synthetic-sciences/openscience/genomic-intelligence/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for genomic-intelligence

Your own site · 80×15
<a href="https://agentmods.dev/skills/synthetic-sciences/openscience/genomic-intelligence"><img src="https://agentmods.dev/badge/skills/synthetic-sciences/openscience/genomic-intelligence.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 150 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 5,589 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00150 $0.05589
Opus 5.5 $0.00060 $0.02236
Sonnet 5.5 $0.00030 $0.01118
Haiku 4.5 $0.00015 $0.00559

Measured 29d ago against content hash 8da9957aa192, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

genomic-intelligence scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 29d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

r = requests.post(f"{BASE}/v1/tasks/{task}/predict", headers=HEADERS, json=body)
Origin

Copies of this mod

1 near-identical copy found in the catalogue:

backend/cli/skills/biology/genomic-intelligence/SKILL.md · 371 lines

How it starts

The opening of the file, as written. The whole thing — 371 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Genomic Intelligence — DNA Sequence Models

Genomic Intelligence (GI) serves transformer DNA language models over six sequence-analysis tasks on managed GPUs. Give it a gene symbol, a genomic region, or a DNA/FASTA sequence; it returns structured predictions — promoter regions, splice sites, enhancer activity, chromatin state, expression (log TPM), and de-novo gene annotation. Nothing runs locally: no model weights, no GPU, no heavy Python stack. It is a thin client over a hosted, versioned inference API.

Official docs: docs.genomicintelligence.ai · REST contract at api.genomicintelligence.ai/v1/openapi.json · hosted MCP server at https://mcp.genomicintelligence.ai/mcp

When to use this skill

Use GI when the user has DNA and wants a model prediction:

  • Find promoters in a genomic region (promoter)
  • Predict splice donor/acceptor sites (splice)
  • Score enhancer activity — developmental & housekeeping (enhancer)
  • Annotate chromatin state across hundreds of tracks (chromatin)
  • Predict expression as log(TPM+1) from a sequence + cell-type context (expression)
  • Annotate genes/transcripts de novo, no reference needed (annotation)
  • Find the genes in a region and predict each one's expression (composite)

Not for local alignment, variant calling, or file I/O — use a local tool (BioPython, bcftools) for those. GI is for model inference from sequence.

Research and development use. Not for clinical or diagnostic decisions.

Two ways to call GI

Hosted MCP server (keyless; preferred on MCP hosts)

GI hosts an MCP server at https://mcp.genomicintelligence.ai/mcp (Streamable HTTP). When your agent host supports MCP, prefer it: it works keyless against a rate- and concurrency-limited public demo tier, and an optional gi_ bearer key raises those limits. It exposes acquisition tools that return a sequence handle (sequence_ref) and predict_* tools that take that handle, so large sequences stay out of the context. See MCP workflow below and references/mcp.md.

Read the full file on GitHub · 371 lines

Files

What ships with it

4 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 29d ago Changed · +5 lines 8da9957aa192
  2. 1mo ago First seen · 366 lines · 150 tokens per session scan A 17790b792930

Subscribe to this mod's changes

genomic-intelligence is a skill published in the GitHub repository synthetic-sciences/openscience (4,004 stars, last pushed 3d ago), licensed Apache-2.0. It adds 150 tokens to every session and 5,589 once invoked, about $0.0006 per session on Opus 5.5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-14.