The open-source AI workbench for scientific research
synthetic-sciences/openscience is an AI workbench that carries out scientific research by reading papers, forming hypotheses, writing and running code, conducting experiments, analyzing results, and preparing reports. Researchers use it for work in machine learning, biology, physics, and chemistry with remote or local models. Catalogue add-ons extend its scientific workflows through skills and instructions.
This repository also configures its own agents. See what openscience tells them →
synthetic-sciences/openscience
Skill Claude CodeCodex
Post-training 4-bit quantization for LLMs with minimal accuracy loss. Use for deploying large models (70B, 405B) on consumer GPUs, when you need 4× memory reduction with <2% perplexity degradation, or for faster inference (3-4× speedup) vs FP16. Integrates with transformers and PEFT for QLoRA fine-tuning.
synthetic-sciences/openscience
Skill Claude CodeCodex
Expert guidance for GRPO/RL fine-tuning with TRL for reasoning and task-specific model training.
synthetic-sciences/openscience
Skill Claude CodeCodex
Half-Quadratic Quantization for LLMs without calibration data. Use when quantizing models to 4/3/2-bit precision without needing calibration datasets, for fast quantization workflows, or when deploying with vLLM or HuggingFace Transformers.
synthetic-sciences/openscience
Skill Claude CodeCodex needs its repo
Add and manage evaluation results in Hugging Face model cards. Supports extracting eval tables from README content, importing scores from Artificial Analysis API, and running custom model evaluations with vLLM/lighteval. Works with the model-index metadata format.
synthetic-sciences/openscience
Skill Claude CodeCodex
This skill should be used when users want to train or fine-tune language models using TRL (Transformer Reinforcement Learning) on Hugging Face Jobs infrastructure. Covers SFT, DPO, GRPO and reward modeling training methods, plus GGUF conversion for local deployment. Includes guidance on the TRL Jobs package, UV…
synthetic-sciences/openscience
Skill Claude CodeCodex
Compress large language models using knowledge distillation from teacher to student models. Use when deploying smaller models with retained performance, transferring GPT-4 capabilities to open-source models, or reducing inference costs. Covers temperature scaling, soft targets, reverse KLD, logit distillation, and…
At most 3 mods per repository are shown here, and a mod shipped inside a plugin is left to that plugin's page — the rest are on their repository pages: