hmdb-database

hmdb-database is a skill for Claude Code, Codex from thesecondfox/skill. It costs 46 tokens per session (1,752 once invoked), scanned A, a copy of hmdb-database, MIT.

A searchable resource for metabolites, the small molecules involved in human biology, including their chemical, clinical, pathway, and measurement data.

In plain words
What is it for?
Use it for metabolomics research, clinical chemistry, biomarker discovery, metabolite identification, and searching NMR or mass-spectrometry spectra.
Why use it?
It brings together information needed to identify metabolites and understand their links to diseases, biomarkers, and biological processes.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/thesecondfox/skill/hmdb-database
Any agent
npx skills add thesecondfox/skill --skill hmdb-database
Clone the repo
git clone --depth 1 https://github.com/thesecondfox/skill

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for hmdb-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/thesecondfox/skill/hmdb-database.svg)](https://agentmods.dev/skills/thesecondfox/skill/hmdb-database)
Your own site
<a href="https://agentmods.dev/skills/thesecondfox/skill/hmdb-database"><img src="https://agentmods.dev/badge/skills/thesecondfox/skill/hmdb-database.svg" alt="Measured on agentmods" height="20"></a>
Per session 46 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,752 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. Scan, not verified.
Origin 100% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00046 $0.01752
Opus 5 $0.00023 $0.00876
Sonnet 5 $0.00009 $0.00350
Haiku 4.5 $0.00005 $0.00175

Measured 2d ago against content hash fb4f6a903010, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-05, from the pricing page.

Security

Grade A, and why

hmdb-database scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

100% identical to hmdb-database — 3 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

Common_Skills/hmdb-database/SKILL.md · 195 lines

How it starts

The opening of the file, as written. The whole thing — 195 lines — stays where its author put it; the contents beside it link to each section on GitHub.

HMDB Database

Overview

The Human Metabolome Database (HMDB) is a comprehensive, freely available resource containing detailed information about small molecule metabolites found in the human body.

When to Use This Skill

This skill should be used when performing metabolomics research, clinical chemistry, biomarker discovery, or metabolite identification tasks.

Database Contents

HMDB version 5.0 (current as of 2025) contains:

  • 220,945 metabolite entries covering both water-soluble and lipid-soluble compounds
  • 8,610 protein sequences for enzymes and transporters involved in metabolism
  • 130+ data fields per metabolite including:
    • Chemical properties (structure, formula, molecular weight, InChI, SMILES)
    • Clinical data (biomarker associations, diseases, normal/abnormal concentrations)
    • Biological information (pathways, reactions, locations)
    • Spectroscopic data (NMR, MS, MS-MS spectra)
    • External database links (KEGG, PubChem, MetaCyc, ChEBI, PDB, UniProt, GenBank)

Core Capabilities

1. Web-Based Metabolite Searches

Access HMDB through the web interface at https://www.hmdb.ca/ for:

Text Searches:

  • Search by metabolite name, synonym, or identifier (HMDB ID)
  • Example HMDB IDs: HMDB0000001, HMDB0001234
  • Search by disease associations or pathway involvement
  • Query by biological specimen type (urine, serum, CSF, saliva, feces, sweat)

Structure-Based Searches:

  • Use ChemQuery for structure and substructure searches
  • Search by molecular weight or molecular weight range
  • Use SMILES or InChI strings to find compounds

Spectral Searches:

  • LC-MS spectral matching
  • GC-MS spectral matching
  • NMR spectral searches for metabolite identification

Advanced Searches:

  • Combine multiple criteria (name, properties, concentration ranges)
  • Filter by biological locations or specimen types
  • Search by protein/enzyme associations

2. Accessing Metabolite Information

When retrieving metabolite data, HMDB provides:

Read the full file on GitHub · 195 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2d ago First seen · 195 lines · 46 tokens per session scan A fb4f6a903010

Subscribe to this mod's changes

hmdb-database is a skill published in the GitHub repository thesecondfox/skill (3 stars, last pushed 5mo ago), licensed MIT. It adds 46 tokens to every session and 1,752 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. It is 100% identical to hmdb-database, differing in 3 lines, and is treated as a copy.

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