thesecondfox/skill

3Stars on the repository
200Mods indexed here, across every type
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thesecondfox/skill

Skill Claude CodeCodex

End-to-end DNA sequencing workflow from FASTQ files to variant calls. Covers QC, alignment with BWA, BAM processing, and variant calling with bcftools or GATK HaplotypeCaller. Use when calling variants from raw sequencing reads.

not rated 3 5mo ago A 59 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end gene regulatory network inference pipeline from processed single-cell data to regulon discovery and perturbation simulation. Supports RNA-only (pySCENIC) and multiome (SCENIC+) paths. Use when building gene regulatory networks from single-cell transcriptomic or multiome data.

not rated 3 5mo ago A 65 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end GWAS workflow from VCF to association results. Covers PLINK QC, population structure correction, and association testing for case-control or quantitative traits. Use when running genome-wide association studies.

not rated 3 5mo ago A 48 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end Hi-C analysis workflow from contact pairs to compartments, TADs, and loops. Covers cooler matrices, cooltools analysis, and visualization. Use when processing Hi-C data to compartments and TADs.

not rated 3 5mo ago A 52 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end imaging mass cytometry workflow from raw acquisitions to spatial cell analysis. Orchestrates image preprocessing, segmentation, phenotyping, and spatial statistics. Use when analyzing imaging mass cytometry data end-to-end.

not rated 3 5mo ago A 51 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end workflow for detecting structural variants from long-read sequencing data. Covers ONT/PacBio alignment with minimap2 and SV calling with Sniffles or cuteSV. Use when detecting structural variants from long reads.

not rated 3 5mo ago A 55 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end MeRIP-seq analysis from FASTQ to m6A peaks and differential methylation. Use when analyzing epitranscriptomic m6A modifications from immunoprecipitation data.

not rated 3 5mo ago A 50 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end genome-scale metabolic modeling from genome sequence to flux predictions. Covers automated reconstruction with CarveMe, model validation with memote, FBA/FVA analysis, and gene essentiality prediction. Use when building metabolic models or predicting metabolic phenotypes from genomic data.

not rated 3 5mo ago A 64 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end multi-omics integration workflow. Orchestrates data harmonization, MOFA/mixOmics integration, factor interpretation, and downstream analysis across transcriptomics, proteomics, metabolomics, and other modalities. Use when integrating multiple omics datasets.

not rated 3 5mo ago A 62 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end multiome workflow for joint scRNA-seq + scATAC-seq analysis. Covers data loading, separate modality processing, and WNN integration with Seurat/Signac. Use when analyzing joint scRNA+scATAC data.

not rated 3 5mo ago A 60 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end outbreak investigation from pathogen isolates to transmission networks. Orchestrates MLST typing, AMR surveillance, phylodynamic dating, and transmission inference with TransPhylo. Use when investigating disease outbreaks or tracking pathogen transmission chains.

not rated 3 5mo ago A 55 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end Ribo-seq analysis from FASTQ to translation efficiency and ORF detection. Use when analyzing ribosome profiling data to study translation.

not rated 3 5mo ago A 40 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end small RNA-seq analysis from FASTQ to differential miRNA expression. Use when analyzing miRNA, piRNA, or other small RNA sequencing data.

not rated 3 5mo ago A 41 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end spatial transcriptomics workflow for Visium/Xenium data. Covers data loading, preprocessing, spatial analysis, domain detection, and visualization with Squidpy. Use when analyzing spatial transcriptomics data.

not rated 3 5mo ago A 50 tokens original MIT

bio-splicing-pipeline

159

thesecondfox/skill

Skill Claude CodeCodex

End-to-end alternative splicing analysis from FASTQ to differential splicing results. Aligns with STAR 2-pass mode, performs junction QC, runs rMATS-turbo for differential analysis, and generates sashimi visualizations. Use when performing comprehensive splicing analysis from raw RNA-seq data.

not rated 3 5mo ago A 66 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end TCR/BCR repertoire analysis from FASTQ to clonotype diversity metrics. Use when analyzing immune repertoire sequencing data from bulk or single-cell experiments.

not rated 3 5mo ago A 40 tokens original MIT

thesecondfox/skill

Skill Claude CodeCodex

End-to-end time-course analysis from expression matrix to temporal patterns and enrichment. Covers temporal DE, Mfuzz soft clustering, optional rhythm detection, GAM trajectory fitting, and per-cluster pathway enrichment. Use when analyzing bulk time-series expression experiments from any omics platform.

not rated 3 5mo ago A 61 tokens original MIT

biopython

162

thesecondfox/skill

Skill Claude CodeCodex

Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use…

not rated 3 5mo ago A 76 tokens copy · 91% MIT

biorxiv-database

163

thesecondfox/skill

Skill Claude CodeCodex needs its repo

Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.

not rated 3 5mo ago A 52 tokens copy · 97% MIT

bioservices

164

thesecondfox/skill

Skill Claude CodeCodex

Unified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt, KEGG, ChEMBL, Reactome) in a single workflow with consistent API. Best for cross-database analysis, ID mapping across services. For quick single-database lookups use gget; for sequence/file manipulation use…

not rated 3 5mo ago A 73 tokens copy · 78% MIT

brenda-database

165

thesecondfox/skill

Skill Claude CodeCodex

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.

not rated 3 5mo ago A 43 tokens copy · 98% MIT

cbioportal-database

166

thesecondfox/skill

Skill Claude CodeCodex

Query cBioPortal for cancer genomics data including somatic mutations, copy number alterations, gene expression, and survival data across hundreds of cancer studies. Essential for cancer target validation, oncogene/tumor suppressor analysis, and patient-level genomic profiling.

not rated 3 5mo ago A 57 tokens copy · 100% MIT

cellxgene-census

167

thesecondfox/skill

Skill Claude CodeCodex

Query the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell atlas. Best for population-scale queries, reference atlas comparisons. For analyzing your own data use scanpy or scvi-tools.

not rated 3 5mo ago A 67 tokens copy · 97% MIT

chembl-database

168

thesecondfox/skill

Skill Claude CodeCodex

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

not rated 3 5mo ago A 45 tokens copy · 97% MIT

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