clawbio-guide

clawbio-guide is a skill for Claude Code, Codex from wentorai/research-plugins. It costs 16 tokens per session (1,181 once invoked), scanned A, original, MIT.

A bioinformatics skill library for OpenClaw that guides common genomics analyses, such as aligning DNA reads, finding genetic variants, studying gene activity, and building evolutionary trees.

In plain words
What is it for?
It helps with genome sequencing analysis, variant calling, RNA sequencing, metagenomics, protein-structure prediction, and other biological data workflows.
Why use it?
It removes the need to assemble each analysis pipeline from separate bioinformatics tools and remember every command. You can describe the task in ordinary language while following established analysis methods.

Skill for Claude CodeCodex

Which agent this was written for is unclear — built for openclaw. Also seen: built for openclaw.

Good fit It helps with genome sequencing analysis, variant calling, RNA sequencing, metagenomics, protein-structure prediction, and other biological data workflows.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/wentorai/research-plugins/clawbio-guide
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add wentorai/research-plugins --skill clawbio-guide
Clone the repo
git clone --depth 1 https://github.com/wentorai/research-plugins

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for clawbio-guide

README.md
[![agentmods](https://agentmods.dev/badge/skills/wentorai/research-plugins/clawbio-guide/github.svg)](https://agentmods.dev/skills/wentorai/research-plugins/clawbio-guide)
Your own site
<a href="https://agentmods.dev/skills/wentorai/research-plugins/clawbio-guide"><img src="https://agentmods.dev/badge/skills/wentorai/research-plugins/clawbio-guide/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for clawbio-guide

Your own site · 80×15
<a href="https://agentmods.dev/skills/wentorai/research-plugins/clawbio-guide"><img src="https://agentmods.dev/badge/skills/wentorai/research-plugins/clawbio-guide.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 16 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,181 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00016 $0.01181
Opus 5 $0.00008 $0.00590
Sonnet 5 $0.00003 $0.00236
Haiku 4.5 $0.00002 $0.00118

Measured 6d ago against content hash c991ade95be6, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

clawbio-guide scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/domains/biomedical/clawbio-guide/SKILL.md · 168 lines

How it starts

The opening of the file, as written. The whole thing — 168 lines — stays where its author put it; the contents beside it link to each section on GitHub.

ClawBio Guide

Overview

ClawBio is a bioinformatics skill library for OpenClaw that provides pre-built skills for common genomics and biological analysis tasks — sequence alignment, variant calling, differential expression, pathway analysis, and more. Each skill encapsulates best-practice bioinformatics pipelines as conversational agent capabilities, making complex analyses accessible through natural language.

Installation

# Install as OpenClaw plugin
openclaw plugins install @clawbio/clawbio

# Or add to your OpenClaw configuration
# In openclaw.config.json:
{
  "plugins": ["@clawbio/clawbio"]
}

Available Skills

Skill Pipeline Description
sequence-align BWA/Bowtie2 Align reads to reference genome
variant-call GATK/BCFtools Call SNPs and indels
rna-seq STAR + DESeq2 Differential expression analysis
chip-seq MACS2 + DiffBind Peak calling and differential binding
metagenomics Kraken2 + Bracken Taxonomic classification
phylogenetics IQ-TREE + RAxML Phylogenetic tree construction
protein-structure AlphaFold/ESMFold Structure prediction
pathway-analysis GSEA + enrichR Gene set enrichment

Usage Examples

RNA-Seq Analysis

# Through OpenClaw conversational interface:
# "Analyze differential expression between treated and control
#  samples in the data/rnaseq/ directory"

# ClawBio executes:
# 1. Quality control (FastQC)
# 2. Trimming (Trimmomatic)
# 3. Alignment (STAR)
# 4. Quantification (featureCounts)
# 5. Differential expression (DESeq2)
# 6. Visualization (volcano plot, MA plot, heatmap)
# 7. Pathway enrichment (GSEA)

Variant Calling

# "Call variants from the whole-genome sequencing data
#  in samples/ against hg38 reference"

# Pipeline:
# 1. Alignment: BWA-MEM2 → sorted BAM
# 2. Preprocessing: MarkDuplicates, BQSR
# 3. Variant calling: GATK HaplotypeCaller
# 4. Filtering: VQSR or hard filters
# 5. Annotation: VEP or SnpEff
# 6. Report: variant statistics, quality metrics

Read the full file on GitHub · 168 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 168 lines · 16 tokens per session scan A c991ade95be6

Subscribe to this mod's changes

clawbio-guide is a skill published in the GitHub repository wentorai/research-plugins (291 stars, last pushed 2mo ago), licensed MIT. It adds 16 tokens to every session and 1,181 once invoked, about $0.0001 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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