clinpgx-database

clinpgx-database is a skill for Claude Code, Codex from x-cmd/skill. It costs 45 tokens per session (5,236 once invoked), scanned A, a copy of clinpgx-database, Apache-2.0.

A programming interface to ClinPGx, a database about pharmacogenomics—the study of how genetic differences affect a person's response to medicines. It combines gene–drug relationships, clinical guidelines, allele functions, and drug-label information.

In plain words
What is it for?
Use it to look up gene–drug interactions, CPIC clinical guidelines, allele functions, pharmacogenomic annotations, and regulatory drug labels.
Why use it?
It brings scattered information about genetic variants and medicines into one queryable source. This can support research into drug metabolism, treatment response, and genotype-guided dosing.

Skill for Claude CodeCodex

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/x-cmd/skill/clinpgx-database
Any agent
npx skills add x-cmd/skill --skill clinpgx-database
Clone the repo
git clone --depth 1 https://github.com/x-cmd/skill

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for clinpgx-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/x-cmd/skill/clinpgx-database.svg)](https://agentmods.dev/skills/x-cmd/skill/clinpgx-database)
Your own site
<a href="https://agentmods.dev/skills/x-cmd/skill/clinpgx-database"><img src="https://agentmods.dev/badge/skills/x-cmd/skill/clinpgx-database.svg" alt="Measured on agentmods" height="20"></a>
Per session 45 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 5,236 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. Scan, not verified.
Origin 89% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5 $0.00045 $0.05236
Opus 5 $0.00023 $0.02618
Sonnet 5 $0.00009 $0.01047
Haiku 4.5 $0.00005 $0.00524

Measured yesterday against content hash 0bd0ad3a953f, method: parsed. Prices are Anthropic first-party input rates as of 2026-08-30, from the pricing page.

Security

Grade A, and why

clinpgx-database scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured yesterday.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/query_clinpgx.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

response = requests.get("https://api.clinpgx.org/v1/gene/CYP2D6")
Origin

This is a copy

89% identical to clinpgx-database — 6 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

data/k-dense-ai/clinpgx-database/SKILL.md · 638 lines

How it starts

The opening of the file, as written. The whole thing — 638 lines — stays where its author put it; the contents beside it link to each section on GitHub.

ClinPGx Database

Overview

ClinPGx (Clinical Pharmacogenomics Database) is a comprehensive resource for clinical pharmacogenomics information, successor to PharmGKB. It consolidates data from PharmGKB, CPIC, and PharmCAT, providing curated information on how genetic variation affects medication response. Access gene-drug pairs, clinical guidelines, allele functions, and drug labels for precision medicine applications.

When to Use This Skill

This skill should be used when:

  • Gene-drug interactions: Querying how genetic variants affect drug metabolism, efficacy, or toxicity
  • CPIC guidelines: Accessing evidence-based clinical practice guidelines for pharmacogenetics
  • Allele information: Retrieving allele function, frequency, and phenotype data
  • Drug labels: Exploring FDA and other regulatory pharmacogenomic drug labeling
  • Pharmacogenomic annotations: Accessing curated literature on gene-drug-disease relationships
  • Clinical decision support: Using PharmDOG tool for phenoconversion and custom genotype interpretation
  • Precision medicine: Implementing pharmacogenomic testing in clinical practice
  • Drug metabolism: Understanding CYP450 and other pharmacogene functions
  • Personalized dosing: Finding genotype-guided dosing recommendations
  • Adverse drug reactions: Identifying genetic risk factors for drug toxicity

Installation and Setup

Python API Access

The ClinPGx REST API provides programmatic access to all database resources. Basic setup:

uv pip install requests

API Endpoint

BASE_URL = "https://api.clinpgx.org/v1/"

Rate Limits:

  • 2 requests per second maximum
  • Excessive requests will result in HTTP 429 (Too Many Requests) response

Authentication: Not required for basic access

Data License: Creative Commons Attribution-ShareAlike 4.0 International License

For substantial API use, notify the ClinPGx team at [email protected]

Core Capabilities

1. Gene Queries

Read the full file on GitHub · 638 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. yesterday First seen · 638 lines · 45 tokens per session scan A 0bd0ad3a953f

Subscribe to this mod's changes

clinpgx-database is a skill published in the GitHub repository x-cmd/skill (26 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 45 tokens to every session and 5,236 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). It is 89% identical to clinpgx-database, differing in 6 lines, and is treated as a copy.

Related

Other skills, from other repositories

kaggle-research-compute

Use when a research or engineering task needs automatic heavy-compute routing to free Kaggle Kernels through the local broker, with agent-driven push, poll, fetch, and a multi-run resume loop across concurrent kernels; free CPU (quota-free) and GPU under a self-imposed weekly GPU-hour cap.

hoanganhduc/ai-agents-skills · 69 tokens

lean-strict-verification-gate

Use when checking whether a Lean artifact can safely support a research claim.

hoanganhduc/ai-agents-skills · 22 tokens

modal-research-compute

Use when a research or engineering task needs automatic heavy-compute routing through the unified local broker, including Modal-backed remote CPU, high-memory CPU, or GPU execution.

hoanganhduc/ai-agents-skills · 39 tokens

digest-bridge

Use when the user wants to extract arXiv IDs or DOIs from research or RSS digests and turn them into getscipapers requests or manifests.

hoanganhduc/ai-agents-skills · 36 tokens

lean-research-library

Use when any Lean formalization task starts (reuse Mathlib and the personal research library before proving anything new) and when it ends (gate finished results into the library and flag mathlib-PR candidates, always asking the user first). Also scaffolds and publishes paper artifacts from the personal template.

hoanganhduc/ai-agents-skills · 64 tokens

venue-ranking-evidence

Use when identifying a journal, conference, or proceedings series from a partial name, acronym, alias, ISSN, or source ID; preserving source-specific rank, quartile, metric, classification, membership, or coverage observations; or proving that the public ICORE detail page displayed one ICORE claim. Live bulk paths are…

hoanganhduc/ai-agents-skills · 116 tokens