opentargets-database

opentargets-database is a skill for Claude Code, Codex from x-cmd/skill. It costs 40 tokens per session (3,237 once invoked), scanned A, a copy of opentargets-database, Apache-2.0.

A programming interface for the Open Targets Platform, a public database linking genes and other drug targets to diseases and medicines.

In plain words
What is it for?
Use it to find disease targets, review evidence, assess safety and druggability, and look up known drugs, trials, and adverse events.
Why use it?
It brings evidence from genetics, biological studies, literature, and chemical data together when assessing possible treatments.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/x-cmd/skill/opentargets-database
Any agent
npx skills add x-cmd/skill --skill opentargets-database
Clone the repo
git clone --depth 1 https://github.com/x-cmd/skill

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for opentargets-database

README.md
[![agentmods](https://agentmods.dev/badge/skills/x-cmd/skill/opentargets-database.svg)](https://agentmods.dev/skills/x-cmd/skill/opentargets-database)
Your own site
<a href="https://agentmods.dev/skills/x-cmd/skill/opentargets-database"><img src="https://agentmods.dev/badge/skills/x-cmd/skill/opentargets-database.svg" alt="Measured on agentmods" height="20"></a>
Per session 40 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,237 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. Scan, not verified.
Origin 89% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00040 $0.03237
Opus 5 $0.00020 $0.01618
Sonnet 5 $0.00008 $0.00647
Haiku 4.5 $0.00004 $0.00324

Measured 2d ago against content hash a307922ca59f, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-05, from the pricing page.

Security

Grade A, and why

opentargets-database scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/query_opentargets.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

89% identical to opentargets-database — 6 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

data/k-dense-ai/opentargets-database/SKILL.md · 373 lines

How it starts

The opening of the file, as written. The whole thing — 373 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Open Targets Database

Overview

The Open Targets Platform is a comprehensive resource for systematic identification and prioritization of potential therapeutic drug targets. It integrates publicly available datasets including human genetics, omics, literature, and chemical data to build and score target-disease associations.

Key capabilities:

  • Query target (gene) annotations including tractability, safety, expression
  • Search for disease-target associations with evidence scores
  • Retrieve evidence from multiple data types (genetics, pathways, literature, etc.)
  • Find known drugs for diseases and their mechanisms
  • Access drug information including clinical trial phases and adverse events
  • Evaluate target druggability and therapeutic potential

Data access: The platform provides a GraphQL API, web interface, data downloads, and Google BigQuery access. This skill focuses on the GraphQL API for programmatic access.

When to Use This Skill

This skill should be used when:

  • Target discovery: Finding potential therapeutic targets for a disease
  • Target assessment: Evaluating tractability, safety, and druggability of genes
  • Evidence gathering: Retrieving supporting evidence for target-disease associations
  • Drug repurposing: Identifying existing drugs that could be repurposed for new indications
  • Competitive intelligence: Understanding clinical precedence and drug development landscape
  • Target prioritization: Ranking targets based on genetic evidence and other data types
  • Mechanism research: Investigating biological pathways and gene functions
  • Biomarker discovery: Finding genes differentially expressed in disease
  • Safety assessment: Identifying potential toxicity concerns for drug targets

Core Workflow

1. Search for Entities

Start by finding the identifiers for targets, diseases, or drugs of interest.

For targets (genes):

from scripts.query_opentargets import search_entities

# Search by gene symbol or name
results = search_entities("BRCA1", entity_types=["target"])
# Returns: [{"id": "ENSG00000012048", "name": "BRCA1", ...}]

Read the full file on GitHub · 373 lines

Files

What ships with it

4 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2d ago First seen · 373 lines · 40 tokens per session scan A a307922ca59f

Subscribe to this mod's changes

opentargets-database is a skill published in the GitHub repository x-cmd/skill (26 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 40 tokens to every session and 3,237 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. It is 89% identical to opentargets-database, differing in 6 lines, and is treated as a copy.

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