molfeat

molfeat is a skill for Claude Code, Codex from Zaoqu-Liu/ScienceClaw. It costs 47 tokens per session (3,778 once invoked), scanned A, a copy of molfeat, MIT.

A Python toolkit that turns chemical structures, such as SMILES strings, into numerical data for machine-learning models. These numerical representations can describe fingerprints, chemical properties, or learned patterns.

In plain words
What is it for?
Use it to prepare molecular data for property prediction, QSAR models, virtual screening, similarity searches, clustering, or other cheminformatics tasks.
Why use it?
Machine-learning models cannot use most chemical structures directly, so they need consistent numerical inputs. This toolkit gathers many ways to create those inputs in one interface.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to prepare molecular data for property prediction, QSAR models, virtual screening, similarity searches, clustering, or other cheminformatics tasks.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/zaoqu-liu/scienceclaw/molfeat
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add Zaoqu-Liu/ScienceClaw --skill molfeat
Clone the repo
git clone --depth 1 https://github.com/Zaoqu-Liu/ScienceClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for molfeat

README.md
[![agentmods](https://agentmods.dev/badge/skills/zaoqu-liu/scienceclaw/molfeat.svg)](https://agentmods.dev/skills/zaoqu-liu/scienceclaw/molfeat)
Your own site
<a href="https://agentmods.dev/skills/zaoqu-liu/scienceclaw/molfeat"><img src="https://agentmods.dev/badge/skills/zaoqu-liu/scienceclaw/molfeat.svg" alt="Measured on agentmods" height="20"></a>
Per session 47 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,778 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 89% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00047 $0.03778
Opus 5 $0.00023 $0.01889
Sonnet 5 $0.00009 $0.00756
Haiku 4.5 $0.00005 $0.00378

Measured 5d ago against content hash c32661864533, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

molfeat scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 5d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

89% identical to molfeat — 6 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/molfeat/SKILL.md · 511 lines

How it starts

The opening of the file, as written. The whole thing — 511 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Molfeat - Molecular Featurization Hub

Overview

Molfeat is a comprehensive Python library for molecular featurization that unifies 100+ pre-trained embeddings and hand-crafted featurizers. Convert chemical structures (SMILES strings or RDKit molecules) into numerical representations for machine learning tasks including QSAR modeling, virtual screening, similarity searching, and deep learning applications. Features fast parallel processing, scikit-learn compatible transformers, and built-in caching.

When to Use This Skill

This skill should be used when working with:

  • Molecular machine learning: Building QSAR/QSPR models, property prediction
  • Virtual screening: Ranking compound libraries for biological activity
  • Similarity searching: Finding structurally similar molecules
  • Chemical space analysis: Clustering, visualization, dimensionality reduction
  • Deep learning: Training neural networks on molecular data
  • Featurization pipelines: Converting SMILES to ML-ready representations
  • Cheminformatics: Any task requiring molecular feature extraction

Installation

uv pip install molfeat

# With all optional dependencies
uv pip install "molfeat[all]"

Optional dependencies for specific featurizers:

  • molfeat[dgl] - GNN models (GIN variants)
  • molfeat[graphormer] - Graphormer models
  • molfeat[transformer] - ChemBERTa, ChemGPT, MolT5
  • molfeat[fcd] - FCD descriptors
  • molfeat[map4] - MAP4 fingerprints

Core Concepts

Molfeat organizes featurization into three hierarchical classes:

1. Calculators (molfeat.calc)

Callable objects that convert individual molecules into feature vectors. Accept RDKit Chem.Mol objects or SMILES strings.

Use calculators for:

  • Single molecule featurization
  • Custom processing loops
  • Direct feature computation

Example:

from molfeat.calc import FPCalculator

calc = FPCalculator("ecfp", radius=3, fpSize=2048)
features = calc("CCO")  # Returns numpy array (2048,)

Read the full file on GitHub · 511 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 5d ago First seen · 511 lines · 47 tokens per session scan A c32661864533

Subscribe to this mod's changes

molfeat is a skill published in the GitHub repository Zaoqu-Liu/ScienceClaw (60 stars, last pushed 5mo ago), licensed MIT. It adds 47 tokens to every session and 3,778 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. It is 89% identical to molfeat, differing in 6 lines, and is treated as a copy.

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