personal-genomics-analysis

personal-genomics-analysis is a skill for Claude Code, Codex from zocomputer/skills. It costs 33 tokens per session (5,279 once invoked), scanned A, original, MIT.

A pipeline that reads raw 23andMe genetic data and produces a searchable genome database, database annotations, visualizations, and a personal report about ancestry, traits, health risks, and drug sensitivities.

In plain words
What is it for?
Use it to examine ancestry estimates, genetic traits, possible health-related variants, and pharmacogenomics findings. These results are informational and should not replace advice from a qualified clinician.
Why use it?
It organizes raw genotype records and compares them with clinical and drug-related databases, making the data easier to query and summarize.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to examine ancestry estimates, genetic traits, possible health-related variants, and pharmacogenomics findings. These results are informational and should not replace advice from a qualified clinician.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/zocomputer/skills/personal-genomics-analysis
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add zocomputer/skills --skill personal-genomics-analysis
Clone the repo
git clone --depth 1 https://github.com/zocomputer/skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for personal-genomics-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/zocomputer/skills/personal-genomics-analysis/github.svg)](https://agentmods.dev/skills/zocomputer/skills/personal-genomics-analysis)
Your own site
<a href="https://agentmods.dev/skills/zocomputer/skills/personal-genomics-analysis"><img src="https://agentmods.dev/badge/skills/zocomputer/skills/personal-genomics-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for personal-genomics-analysis

Your own site · 80×15
<a href="https://agentmods.dev/skills/zocomputer/skills/personal-genomics-analysis"><img src="https://agentmods.dev/badge/skills/zocomputer/skills/personal-genomics-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 33 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 5,279 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00033 $0.05279
Opus 5 $0.00016 $0.02639
Sonnet 5 $0.00007 $0.01056
Haiku 4.5 $0.00003 $0.00528

Measured 9d ago against content hash 5266347045f5, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

personal-genomics-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Community/personal-genomics-analysis/SKILL.md · 657 lines

How it starts

The opening of the file, as written. The whole thing — 657 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Personal Genomics Analysis Pipeline

How to Use This Prompt

This prompt transforms raw 23andMe genome data into a comprehensive, queryable genomics knowledge base with clinical annotations and personalized health insights.

Prerequisites:

  • 23andMe raw genome data file (V3, V4, or V5 format, typically ~600k-900k SNPs)
  • The file should be in tab-delimited format with columns: rsid, chromosome, position, genotype
  • Approximately 10-15 minutes of processing time
  • ~5GB of disk space for databases

What This Pipeline Creates:

  1. genome.db - Your personal genome database (631k SNPs, ~50MB)
  2. clinvar.db - Clinical variant database (3.8M variants, 472k pathogenic, ~600MB)
  3. pharmgkb.db - Pharmacogenomics database (drug-gene interactions)
  4. Analysis scripts - Reusable Python tools for querying your genome
  5. Visualizations - Ancestry charts, trait summaries
  6. Personalized report - Comprehensive markdown document with all findings

What You'll Discover:

  • 🧬 Ancestry composition - Estimated genetic ancestry from key markers
  • 💊 Pharmacogenomics - How you metabolize common drugs (critical for medical records!)
  • 🧠 Cognitive/behavioral traits - COMT, OXTR, BDNF variants
  • 💪 Athletic performance - ACTN3, ACE genes
  • ❤️ Health risks - Diabetes, cardiovascular, Alzheimer's markers
  • 🍽️ Dietary genetics - Lactose tolerance, caffeine metabolism, taste perception
  • 👁️ Physical traits - Eye color, earwax type, hair characteristics
  • 🚨 Pathogenic variants - Screened against 472k known disease variants

Warning: This analysis is for informational and research purposes only. It is not a substitute for professional genetic counseling or medical advice. Critical findings (especially pharmacogenomics) should be shared with your healthcare provider.

Database Schemas

1. genome.db (Your Personal Genome)

CREATE TABLE snps (
    rsid TEXT PRIMARY KEY,
    chromosome TEXT NOT NULL,
    position INTEGER NOT NULL,
    genotype TEXT NOT NULL
);

CREATE INDEX idx_chromosome ON snps(chromosome);
CREATE INDEX idx_position ON snps(position);
CREATE INDEX idx_chrom_pos ON snps(chromosome, position);

Read the full file on GitHub · 657 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 657 lines · 33 tokens per session scan A 5266347045f5

Subscribe to this mod's changes

personal-genomics-analysis is a skill published in the GitHub repository zocomputer/skills (45 stars, last pushed 1mo ago), licensed MIT. It adds 33 tokens to every session and 5,279 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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