Skill Claude CodeCodex
Precheck biological and interpretation risks before selecting perturbation targets or guide designs.
Skill Claude CodeCodex
Precheck biological and interpretation risks before selecting perturbation targets or guide designs.
Skill Claude CodeCodex
Summarize the current literature consensus, disagreements, and evidence strength for a biological question.
Skill Claude CodeCodex
Validate whether a marker set supports a proposed cell type or cell state and explain the main caveats.
Skill Claude CodeCodex
Build positive and negative marker panels for a cell type or state and explain the confidence of the proposed panel.
Skill Claude CodeCodex
Convert between molarity, mass, and volume using molecular weight.
Skill Claude CodeCodex
Look up gene description and location via NCBI Gene (esearch/efetch).
Skill Claude CodeCodex
Advise on normalization for scRNA (library size, log, SCTransform, etc.).
Skill Claude CodeCodex
Map genes across species and explain confidence, ambiguity, and biological caveats.
Skill Claude CodeCodex
Triage a paper for biological relevance, extract the main claims, and separate evidence-backed takeaways from abstract-only impressions.
Skill Claude CodeCodex
Check whether paralogs or compensatory family members may weaken interpretation of a perturbation target.
Skill Claude CodeCodex
Look up pathway or GO/Reactome/KEGG term definitions and key genes.
Skill Claude CodeCodex
Suggest a control strategy for perturbation experiments, including non-targeting, positive, and interpretation controls.
Skill Claude CodeCodex
Compare gene signatures across perturbations and suggest clustering or grouping.
Skill Claude CodeCodex
Estimate the cell budget and practical coverage needed for a Perturb-seq design.
Skill Claude CodeCodex
Generate a 96- or 384-well plate map for perturbations and replicates.
Skill Claude CodeCodex
Advise on PCR primer design (Tm, length, GC%, avoiding secondary structure).
Skill Claude CodeCodex
Retrieve a lab protocol or SOP from the local knowledge base and summarize the parts that matter for the current experiment.
Skill Claude CodeCodex
Recommend a replicate-aware pseudobulk strategy for single-cell differential expression and explain the design choices.
Skill Claude CodeCodex
Fetch and summarize a PubMed article by PMID (abstract, key methods, key findings).
Skill Claude CodeCodex
Search PubMed for articles by query; return top N PMIDs with titles, year, journal, and link.
Skill Claude CodeCodex
Parse common pipeline log/output and summarize metrics and status.
Skill Claude CodeCodex
Propose safe commands and directory hygiene for running a pipeline.
Skill Claude CodeCodex
Turn single-cell RNA-seq summary metrics into a practical QC checklist with explicit assumptions and threshold recommendations.
Skill Claude CodeCodex
Suggest Scanpy/Python commands for basic scRNA QC (filtering, mito, UMI).