pseudobulk_design_helper

pseudobulk_design_helper is a skill for Claude Code from Azealoo/miniAgent. It costs 26 tokens per session (474 once invoked), scanned A, original, no licence file.

A guide for choosing a pseudobulk analysis strategy for single-cell differential expression. Pseudobulk combines cells from the same biological replicate before statistical testing.

In plain words
What is it for?
It is for recommending a replicate-aware design and explaining its statistical choices.
Why use it?
It helps account for biological replicates instead of treating every individual cell as an independent sample.

Skill for Claude Code

Written for Claude Code: user-invocable in frontmatter.

Good fit It is for recommending a replicate-aware design and explaining its statistical choices.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/azealoo/miniagent/pseudobulk_design_helper
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add Azealoo/miniAgent --skill pseudobulk_design_helper
Clone the repo
git clone --depth 1 https://github.com/Azealoo/miniAgent

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for pseudobulk_design_helper

README.md
[![agentmods](https://agentmods.dev/badge/skills/azealoo/miniagent/pseudobulk_design_helper.svg)](https://agentmods.dev/skills/azealoo/miniagent/pseudobulk_design_helper)
Your own site
<a href="https://agentmods.dev/skills/azealoo/miniagent/pseudobulk_design_helper"><img src="https://agentmods.dev/badge/skills/azealoo/miniagent/pseudobulk_design_helper.svg" alt="Measured on agentmods" height="20"></a>
Per session 26 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 474 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00026 $0.00474
Opus 5 $0.00013 $0.00237
Sonnet 5 $0.00005 $0.00095
Haiku 4.5 $0.00003 $0.00047

Measured 7d ago against content hash d1b92d0d1189, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-07, from the pricing page.

Security

Grade A, and why

pseudobulk_design_helper scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 7d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

backend/skills/pseudobulk_design_helper/SKILL.md · 59 lines

The source is not reproduced here

No licence file

A repository with no LICENSE is all rights reserved by default, so the body is not copied here. The metadata, the measurements and the link are.

Read it on GitHub

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 7d ago First seen · 59 lines · 26 tokens per session scan A d1b92d0d1189

Subscribe to this mod's changes

pseudobulk_design_helper is a skill published in the GitHub repository Azealoo/miniAgent (2 stars, last pushed 2mo ago), with no licence file. It adds 26 tokens to every session and 474 once invoked, about $0.0001 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

Related

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spatial-de

Load when ranking spatial cluster markers or comparing two spatial groups in spatial transcriptomics. Skip when the data is single-cell (use sc-de); bulk (use bulkrna-de); spatially variable expression discovery (use spatial-genes).

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spatial-condition-comparison

Experimental condition comparison using pseudobulk differential expression with proper multi-sample statistics.

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sc-de

Load when finding marker genes per cluster or comparing condition expression in single-cell RNA-seq. Skip when the data is bulk (use bulkrna-de); spatial (use spatial-de); cluster-only markers without conditions (use sc-markers).

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proteomics-de

Load when computing two-group differential protein abundance (group2 vs group1, log2FC + p-value + BH-adjusted FDR) via Welch t-test, equal-variance t-test, or Mann-Whitney on a wide protein × sample CSV. Skip when you need multi-condition DE (run pairwise contrasts manually); label-based TMT linear-mixed models.

TianGzlab/OmicsClaw · 79 tokens

bulkrna-de

Load when comparing gene expression between two conditions in bulk RNA-seq count data. Skip when the data is single-cell (use sc-de); spatial (use spatial-de); you need exon-level alternative splicing (use bulkrna-splicing).

TianGzlab/OmicsClaw · 54 tokens