FBA simulation agent. Runs standard FBA, parsimonious FBA, Flux Variability Analysis, and gene/reaction knockout simulations using COBRApy. Use after a validated metabolic model is available and the user wants to compute growth rates, flux distributions, or knockout phenotypes.
Metabolic flux analysis agent. Performs gene essentiality analysis, phenotypic phase plane construction, flux sampling, and subsystem-level pathway analysis. Use after FBA simulations are complete and the user wants deeper phenotypic characterisation or to identify metabolic engineering targets.
Metabolic phenotype interpretation and publication figure agent. Compares wild-type vs. mutant flux distributions, predicts maximum theoretical product yields, identifies metabolic bottlenecks, and generates publication-quality metabolic maps and charts. Use after flux analysis is complete and the user needs…
Genome-scale metabolic model builder. Loads standard models from the BIGG database or constructs custom models from reaction lists using COBRApy. Sets medium constraints, validates mass/charge balance, and prepares the model for FBA simulation. Use when the user specifies an organism, BIGG model ID, or a custom set of…
Statistical comparison agent. Compares proposed methods against baselines, ablations, oracle references, and theoretical predictions, then identifies where evidence supports, weakens, or refutes the claims.
Statistical experiment designer and executor. Designs simulations, empirical studies, perturbations, diagnostics, and evaluation protocols that test the formulation, method proposal, and theoretical predictions.
Statistical method proposal agent. Proposes candidate methods, baselines, variants, diagnostics, and ablations that directly address the formal problem formulation.
Statistical problem formulation agent. Converts a prompt, topic file, paper idea, or dataset description into a rigorous mathematical/statistical problem statement with notation, data model, estimand, assumptions, hypotheses, evaluation criteria, and theory targets.
Statistical research quality auditor. Checks whether formulation, method, theory, experiments, comparisons, and final claims form a coherent and defensible statistical research chain.
Statistical result synthesis agent. Writes the final research narrative, combining formulation, proposed method, theory, experiments, comparisons, and limitations into a coherent report.
Statistical theory analysis agent. Derives or sketches theoretical properties of the proposed methods, including identifiability, bias, variance, consistency, asymptotic behavior, coverage, error bounds, robustness, and limitations under stated assumptions.