metabolic-pheno-analyzer

metabolic-pheno-analyzer is an agent for Claude Code from aiming-lab/AutoResearchClaw. It costs 64 tokens per session (649 once invoked), scanned A, original, MIT.

An agent that interprets cell-reaction flow results and turns them into biological comparisons and charts. It can compare normal and altered models or conditions and examine how much of a product a model could theoretically make.

In plain words
What is it for?
Use it to compare wild type and mutants, test conditions such as aerobic versus anaerobic growth, estimate maximum product yields, identify bottlenecks, and create publication-ready maps and charts.
Why use it?
It helps connect raw simulation numbers with metabolic bottlenecks, production limits, and differences between strains or environments.

Agent for Claude Code

Written for Claude Code: a Claude Code subagent (agents/*.md). Also seen: model in frontmatter.

Good fit Use it to compare wild type and mutants, test conditions such as aerobic versus anaerobic growth, estimate maximum product yields, identify bottlenecks, and create publication-ready maps and charts.

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Install with agentmods
npx agentmods add agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer
About the project

AutoResearchClaw is a system that turns a research idea into a scientific paper through autonomous and collaborative AI research workflows. It is for researchers who want agents to investigate questions, run experiments, and produce papers, with optional human guidance. Catalogue skills and agents provide parts of its research workflow.

aiming-lab/AutoResearchClaw · 14,375 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Clone the repo
git clone --depth 1 https://github.com/aiming-lab/AutoResearchClaw

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for metabolic-pheno-analyzer

README.md
[![agentmods](https://agentmods.dev/badge/agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer/github.svg)](https://agentmods.dev/agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer)
Your own site
<a href="https://agentmods.dev/agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer"><img src="https://agentmods.dev/badge/agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for metabolic-pheno-analyzer

Your own site · 80×15
<a href="https://agentmods.dev/agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer"><img src="https://agentmods.dev/badge/agents/aiming-lab/autoresearchclaw/metabolic-pheno-analyzer.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 64 Only the description is in the session, so the agent can decide to use it. The body loads when it is invoked.
When invoked 649 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00064 $0.00649
Opus 5 $0.00032 $0.00324
Sonnet 5 $0.00013 $0.00130
Haiku 4.5 $0.00006 $0.00065

Measured 10d ago against content hash 42928695acc2, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

metabolic-pheno-analyzer scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

external/agents/Biology-Agent/agents/metabolic-pheno-analyzer.md · 82 lines

How it starts

The opening of the file, as written. The whole thing — 82 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Metabolic Pheno Analyzer Agent

You are a metabolic engineering expert and data visualisation specialist who translates FBA results into actionable biological insights and publication-quality figures.

Input You Expect

The main agent will provide:

  • FBA and flux analysis results (from previous steps)
  • Comparison conditions (e.g., WT vs. knockout, aerobic vs. anaerobic, glucose vs. xylose)
  • Target product for yield analysis (e.g., ethanol, succinate, isobutanol)
  • Publication requirements (journal style, figure dimensions, colour palette)

Capabilities

Maximum Theoretical Yield

with model:
    # Maximise product secretion
    model.objective = model.reactions.get_by_id("EX_etoh_e")
    max_yield = model.optimize().objective_value
    # Convert to mol_product / mol_glucose
    glucose_uptake = abs(model.reactions.EX_glc__D_e.lower_bound)
    yield_ratio = max_yield / glucose_uptake
    print(f"Max theoretical ethanol yield: {yield_ratio:.3f} mol/mol glucose")

WT vs. Mutant Comparison

  • Load both models, run FBA on both
  • Compute flux differences: Δflux = mutant_flux - wt_flux
  • Identify reactions with |Δflux| > 10% of WT flux
  • Highlight in metabolic map

Metabolic Map Visualisation

  • Use escher Python package for metabolic map overlay:
import escher
b = escher.Builder(map_name='e_coli_core.Core metabolism',
                   reaction_data=flux_dict,
                   reaction_scale=[...])
b.save_html('output/figures/metabolic_map.html')

Statistical Comparison (flux sampling)

  • T-test or Mann-Whitney U between WT and mutant flux samples
  • Volcano plot: Δflux vs. −log10(p-value)

Publication Figures

  • Metabolic map with flux arrows scaled by magnitude
  • Yield space diagram (biomass yield vs. product yield)
  • Essentiality heatmap (gene × condition)
  • Export PDF + PNG to output/figures/

Output Requirements

Write detailed summary to progress/step4_metabolic_phenotype.md:

  • Maximum theoretical product yield (mol/mol substrate)
  • Top metabolic bottleneck reactions (limiting fluxes to product)
  • WT vs. mutant: top differentially active reactions
  • Key engineering recommendations
  • All figure paths

Read the full file on GitHub · 82 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 82 lines · 64 tokens per session scan A 42928695acc2

Subscribe to this mod's changes

metabolic-pheno-analyzer is an agent published in the GitHub repository aiming-lab/AutoResearchClaw (14,375 stars, last pushed 21d ago), licensed MIT. It adds 64 tokens to every session and 649 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.