ct-status-diff

ct-status-diff is a skill for Claude Code from agentii-ai/agentii-investment-intelligence. It costs 115 tokens per session (1,689 once invoked), scanned A, original, Apache-2.0.

A weekly report that compares stored snapshots of clinical-trial records to show status changes. Clinical trials are studies that test medical treatments in people.

In plain words
What is it for?
Use it to monitor trials on a watchlist and identify changed completion dates, recruitment status, enrollment size, or risk signals.
Why use it?
It makes delays, terminations, recruitment changes, and enrollment changes visible without manually comparing registry records.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Part of the bio-pharm plugin — 15 skills shipped together

Good fit Use it to monitor trials on a watchlist and identify changed completion dates, recruitment status, enrollment size, or risk signals.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/agentii-ai/agentii-investment-intelligence/ct-status-diff
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add agentii-ai/agentii-investment-intelligence --skill ct-status-diff
Clone the repo
git clone --depth 1 https://github.com/agentii-ai/agentii-investment-intelligence

Made for: Claude Code.

Or install bio-pharm, the plugin that ships this one along with the rest of its 15 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for ct-status-diff

README.md
[![agentmods](https://agentmods.dev/badge/skills/agentii-ai/agentii-investment-intelligence/ct-status-diff/github.svg)](https://agentmods.dev/skills/agentii-ai/agentii-investment-intelligence/ct-status-diff)
Your own site
<a href="https://agentmods.dev/skills/agentii-ai/agentii-investment-intelligence/ct-status-diff"><img src="https://agentmods.dev/badge/skills/agentii-ai/agentii-investment-intelligence/ct-status-diff/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for ct-status-diff

Your own site · 80×15
<a href="https://agentmods.dev/skills/agentii-ai/agentii-investment-intelligence/ct-status-diff"><img src="https://agentmods.dev/badge/skills/agentii-ai/agentii-investment-intelligence/ct-status-diff.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 115 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,689 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00115 $0.01689
Opus 5.5 $0.00046 $0.00676
Sonnet 5.5 $0.00023 $0.00338
Haiku 4.5 $0.00012 $0.00169

Measured 1mo ago against content hash 44f3ef00f00b, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

ct-status-diff scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 1mo ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

marketplace-beachhead/plugins/bio-pharm/skills/agentii/ct-status-diff/SKILL.md · 153 lines

How it starts

The opening of the file, as written. The whole thing — 153 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Methodology inspired by publicly taught clinical-trial monitoring frameworks; all text is an original paraphrase.

Defaults

Parameter Default Value Rationale
window latest two snapshots The diff is always between consecutive stored states
categories all 11 Complete change report; filter on request
risk_flags on Terminated / Downsized are surfaced first
gap_statement on Missing snapshot weeks are stated, never inferred

Preflight

Run canonical pre-flight per contracts/preflight.md. Include the X-Agentii-Trace header on every tool call per contracts/x-agentii-trace-header.md — carry the _run_id from your first tool result and name yourself (and your parent, if you were spawned). Confirm the snapshot coverage via get_ct_status_changes before framing any readout.

Triggers

  • "What changed on clinicaltrials.gov for my coverage this week?"
  • "Which of [ticker]'s trials moved this week?"
  • "Any trial delays or accelerations in my watchlist?"
  • "Flag every terminated or downsized trial since last week."
  • "Did any recruitment complete for [ticker]?"
  • "Show the previous and new primary-completion dates for [drug]'s program."
  • "Which trials were upsized this week?"
  • "Is [trial]'s enrollment collapsing?"
  • "Summarize the week's trial-registry changes for the sector."
  • "What should I re-check ahead of [readout] based on registry moves?"
  • "Compare this week's diff to the month-ago diff."

Production Grounding

  • The diff is a stored-state comparison: every row pairs a NEW value with the PREVIOUS value from the prior snapshot — the previous-value column is the discipline; a row without both is a defect.
  • The 11-category taxonomy: New / Suspended / Withdrawn / Terminated / Recruiting / Recruitment-Complete / Completed / Ahead / Delayed / Upsized / Downsized.
  • Risk signals: Terminated and Downsized (enrollment collapse is the earliest visible distress). Re-timing alerts: Ahead / Delayed primary-completion moves.
  • Recruitment-Complete means the readout clock has started — treat it as a catalyst-date confirmation.
  • Gap windows: if snapshots are not consecutive archive writes, the gap is stated on the rows — a change is never attributed across a missing week.
  • Determinism: identical snapshots yield byte-identical diffs; never invent an intermediate state.
  • Badge discipline: [FACT] registry rows, [DEDUCTED] interpretations, [VIEW] positioning, with the summary table.

Read the full file on GitHub · 153 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 1mo ago Changed 44f3ef00f00b
  2. 1mo ago First seen · 153 lines · 115 tokens per session scan A a25101ced681

Subscribe to this mod's changes

ct-status-diff is a skill published in the GitHub repository agentii-ai/agentii-investment-intelligence (208 stars, last pushed yesterday), licensed Apache-2.0. It adds 115 tokens to every session and 1,689 once invoked, about $0.0005 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-15.

Related

Other skills, from other repositories

neuropixels-analysis

Analyzes Neuropixels extracellular recordings end-to-end with SpikeInterface. Covers loading SpikeGLX/Open Ephys/NWB data, preprocessing, drift/motion correction, Kilosort4 (and CPU) spike sorting, quality metrics, and unit curation (threshold-based, model-based UnitRefine, and AI-assisted visual review). Use when…

K-Dense-AI/scientific-agent-skills · 99 tokens

onekgpd

Queries the 1000 Genomes Project dataset (3,202 whole-genome-sequenced individuals, GRCh38) at the level of individual participants. Use when a question is about individuals or variants in the 1000 Genomes Project cohort: which individuals carry variants matching specific criteria in a gene or region, which…

K-Dense-AI/scientific-agent-skills · 143 tokens

biopython

Provides Biopython workflows for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Supports batch processing, custom molecular-biology pipelines, BLAST automation, structure analysis, and motif analysis.

K-Dense-AI/scientific-agent-skills · 65 tokens

experimental-design

Designs experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone is planning a study, asks how to assign subjects/samples to groups, mentions randomization, blocking, stratification, controls…

K-Dense-AI/scientific-agent-skills · 201 tokens

exploratory-data-analysis

Performs bounded, local exploratory analysis of explicitly supported scientific files. Supports redacted CSV/TSV/JSON profiles; optional NumPy, HDF5, FASTA/FASTQ, and basic image metadata inspection; missingness/leakage audits; outlier and transformation sensitivity; and rigorous EDA report scaffolds. Other domain…

K-Dense-AI/scientific-agent-skills · 83 tokens

matlab

Builds, reviews, migrates, and plans MATLAB or GNU Octave numerical workflows. Use for arrays, tabular/time data, tests, projects, graphics, MAT files, and explicit Python interoperability.

K-Dense-AI/scientific-agent-skills · 44 tokens