cellxgene-census

cellxgene-census is a skill for Claude Code from agentlas-ai/agentlas-desktop. It costs 97 tokens per session (2,728 once invoked), scanned A, a copy of cellxgene-census, Apache-2.0.

A programmatic interface to the CZ CELLxGENE Census, a versioned public collection of standardized single-cell and spatial gene-expression data.

In plain words
What is it for?
It helps find cells by type, tissue, or disease; retrieve expression data and summaries; access embeddings and spatial data; and compare or model data across public datasets.
Why use it?
It lets you query selected cells and metadata without first downloading an entire large dataset, while keeping analyses tied to a specific data release.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Good fit It helps find cells by type, tissue, or disease; retrieve expression data and summaries; access embeddings and spatial data; and compare or model data across public datasets.

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Install with agentmods
npx agentmods add skills/agentlas-ai/agentlas-desktop/cellxgene-census
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add agentlas-ai/agentlas-desktop --skill cellxgene-census
Clone the repo
git clone --depth 1 https://github.com/agentlas-ai/agentlas-desktop

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for cellxgene-census

README.md
[![agentmods](https://agentmods.dev/badge/skills/agentlas-ai/agentlas-desktop/cellxgene-census/github.svg)](https://agentmods.dev/skills/agentlas-ai/agentlas-desktop/cellxgene-census)
Your own site
<a href="https://agentmods.dev/skills/agentlas-ai/agentlas-desktop/cellxgene-census"><img src="https://agentmods.dev/badge/skills/agentlas-ai/agentlas-desktop/cellxgene-census/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for cellxgene-census

Your own site · 80×15
<a href="https://agentmods.dev/skills/agentlas-ai/agentlas-desktop/cellxgene-census"><img src="https://agentmods.dev/badge/skills/agentlas-ai/agentlas-desktop/cellxgene-census.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 97 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,728 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 92% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00097 $0.02728
Opus 5.5 $0.00039 $0.01091
Sonnet 5.5 $0.00019 $0.00546
Haiku 4.5 $0.00010 $0.00273

Measured 1mo ago against content hash 3e7cee2dc141, method: parsed. Prices are Anthropic first-party input rates as of 2026-10-07, from the pricing page.

Security

Grade A, and why

cellxgene-census scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 1mo ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

92% identical to cellxgene-census — 96 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

plugins/agentlas-science-skills/skills/cellxgene-census/SKILL.md · 301 lines

How it starts

The opening of the file, as written. The whole thing — 301 lines — stays where its author put it; the contents beside it link to each section on GitHub.

CZ CELLxGENE Census

Overview

The CZ CELLxGENE Census provides programmatic access to a comprehensive, versioned collection of standardized single-cell and spatial transcriptomics data from CZ CELLxGENE Discover. This skill enables efficient querying and analysis of public Census releases without downloading whole datasets first.

The Census includes:

  • 217+ million total cells and 125+ million unique cells in the 2025-11-08 stable LTS release
  • 1,845 datasets in the 2025-11-08 stable LTS release
  • Human, mouse, marmoset, rhesus macaque, and chimpanzee data in the current schema
  • Standardized metadata (cell types, tissues, diseases, donors)
  • Raw gene expression matrices and source H5AD lookup/download helpers
  • Pre-calculated summary counts, embeddings, and spatial data
  • Integration with AnnData, Scanpy, TileDB-SOMA, TileDB-SOMA-ML, and other analysis tools

When to Use This Skill

This skill should be used when:

  • Querying single-cell expression data by cell type, tissue, or disease
  • Exploring available single-cell datasets and metadata
  • Training machine learning models on single-cell data
  • Performing large-scale cross-dataset analyses
  • Integrating Census data with scanpy or other analysis frameworks
  • Computing statistics across millions of cells
  • Accessing pre-calculated embeddings or model predictions

Installation and Setup

Install the Census API:

uv pip install "cellxgene-census==1.17.*"

For spatial workflows:

uv pip install "cellxgene-census[spatial]==1.17.*" "spatialdata[extra]>=0.2.5"

For PyTorch model training, use TileDB-SOMA-ML. The old cellxgene_census.experimental.ml loaders are deprecated:

uv pip install "cellxgene-census==1.17.*" tiledbsoma-ml

Core Workflow Patterns

Eight patterns, each with code, are in references/core_workflow_patterns.md:

  1. Opening the Census — always pin census_version so an analysis stays reproducible.
  2. Exploring Census information — available datasets, cell counts, and summary tables.
  3. Querying expression data — small to medium scale into an AnnData.
  4. Large-scale queries — out-of-core processing when the slice will not fit in memory.
  5. Machine learning with PyTorch — the Census data loaders.
  6. Spatial Census data — accessing spatial assays.
  7. Integration with Scanpy — handing a Census slice to a standard Scanpy workflow.
  8. Multi-dataset integration — combining datasets and handling batch effects.

Read the full file on GitHub · 301 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 1mo ago First seen · 301 lines · 97 tokens per session scan A 3e7cee2dc141

Subscribe to this mod's changes

cellxgene-census is a skill published in the GitHub repository agentlas-ai/agentlas-desktop (6 stars, last pushed today), licensed Apache-2.0. It adds 97 tokens to every session and 2,728 once invoked, about $0.0004 per session on Opus 5.5. A static security scan graded it A with 0 findings. It is 92% identical to cellxgene-census, differing in 96 lines, and is treated as a copy.

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