clinical-research

clinical-research is a skill for Claude Code from aks-builds/healthcareskills. It costs 311 tokens per session (4,533 once invoked), scanned A, original, MIT.

Guidance for building clinical research software and workflows. Clinical research is the organized study of treatments, diseases, or health outcomes using data from participants or records.

In plain words
What is it for?
Use it to design study forms, research-data integrations, and workflows for clinical trials, observational studies, registries, and related projects.
Why use it?
It helps teams turn a study plan into reliable data while considering participant protection, regulations, and the systems used by research sites.

Skill for Claude Code

Written for Claude Code: shipped in a Claude Code plugin.

Part of the healthcare-skills plugin — 41 skills shipped together , and of healthcare-skills

Good fit Use it to design study forms, research-data integrations, and workflows for clinical trials, observational studies, registries, and related projects.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/aks-builds/healthcareskills/clinical-research
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aks-builds/healthcareskills --skill clinical-research
Clone the repo
git clone --depth 1 https://github.com/aks-builds/healthcareskills

Made for: Claude Code.

Or install healthcare-skills, the plugin that ships this one along with the rest of its 41 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for clinical-research

README.md
[![agentmods](https://agentmods.dev/badge/skills/aks-builds/healthcareskills/clinical-research/github.svg)](https://agentmods.dev/skills/aks-builds/healthcareskills/clinical-research)
Your own site
<a href="https://agentmods.dev/skills/aks-builds/healthcareskills/clinical-research"><img src="https://agentmods.dev/badge/skills/aks-builds/healthcareskills/clinical-research/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for clinical-research

Your own site · 80×15
<a href="https://agentmods.dev/skills/aks-builds/healthcareskills/clinical-research"><img src="https://agentmods.dev/badge/skills/aks-builds/healthcareskills/clinical-research.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 311 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,533 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00311 $0.04533
Opus 5 $0.00156 $0.02266
Sonnet 5 $0.00062 $0.00907
Haiku 4.5 $0.00031 $0.00453

Measured 12d ago against content hash f5559fb84a74, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

clinical-research scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/clinical-research/SKILL.md · 309 lines

How it starts

The opening of the file, as written. The whole thing — 309 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Clinical Research

You are an expert in clinical research informatics — the systems, standards, and regulatory workflows that turn a protocol into clean, regulator-ready data while protecting human subjects. Your goal is to help engineers, data managers, study coordinators, and informaticists choose tools, design eCRFs and integrations, and meet GCP and 21 CFR Part 11 expectations without inventing requirements that don't apply to the specific study type.

Initial Assessment

Check .agents/healthcare-context.md (fallback: .claude/healthcare-context.md) before answering. Focus on:

  • Sponsor type — academic / NIH-funded, industry sponsor, sponsor-investigator, CRO, site network.
  • Study phase and type — Phase 1-4, IND/IDE, post-market, pragmatic, observational, registry, RWE, DCT.
  • Regulatory scope — FDA-regulated (drug, device, biologic), EMA / MHRA, ICH-regulated, Common Rule, FDA-exempt research, quality improvement.
  • Geography — US single-site, US multi-site, EU (GDPR + CTR 536/2014), global.
  • EDC and CTMS in use — affects integration patterns and Part 11 posture.
  • Site mix — academic medical center, community, virtual / DCT, mixed.

If the file is missing, ask only what is needed and offer to save it.


Study Types

Type Description Typical regulatory frame
Randomized Controlled Trial (RCT) Prospective, randomized, controlled IND/IDE if regulated product; ICH GCP; full IRB
Single-arm / open-label Prospective, no concurrent control IND/IDE; ICH GCP
Observational No protocol-driven intervention May be IRB-exempt or expedited
Registry Long-term observational cohort IRB review of registry protocol; ongoing consent management
Pragmatic trial Embedded in routine care Often uses cluster randomization, waiver of consent considerations
Real-world evidence (RWE) study Secondary use of EHR / claims / wearables HIPAA waiver or de-identified data; FDA RWE guidance
Decentralized clinical trial (DCT) Site-light; tech-mediated participation Same regulatory bar; new operational risks
Post-marketing surveillance / Phase 4 Marketed product safety/effectiveness Often FDA-mandated (REMS, PMR/PMC)

Read the full file on GitHub · 309 lines

Files

What ships with it

4 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 309 lines · 311 tokens per session scan A f5559fb84a74

Subscribe to this mod's changes

clinical-research is a skill published in the GitHub repository aks-builds/healthcareskills (1 stars, last pushed 2d ago), licensed MIT. It adds 311 tokens to every session and 4,533 once invoked, about $0.0016 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

Related

Other skills, from other repositories

pkpd-modeling

Pharmacokinetic and pharmacodynamic modelling and simulation - non-compartmental analysis, compartmental and population PK, PK/PD and exposure-response, TMDD, PBPK orientation, bioequivalence, allometric scaling and first-in-human dose, drug interaction prediction, and Bayesian therapeutic drug monitoring. Use when…

K-Dense-AI/scientific-agent-skills · 273 tokens

statistical-analysis

Guided statistical analysis for research data - test selection, assumption checking, effect sizes, power analysis, Bayesian alternatives, and APA-formatted reporting. Use whenever a user wants to compare groups, test a hypothesis, analyze experimental or survey data, check statistical assumptions, compute required…

K-Dense-AI/scientific-agent-skills · 111 tokens

biopython

Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use…

K-Dense-AI/scientific-agent-skills · 76 tokens

hypothesis-generation

Formulate evidence-bounded scientific questions, candidate hypotheses, rival explanations, causal or associational claims, discriminating predictions, measurements, and preregistration-ready analysis plans. Use when turning observations or preliminary findings into transparent, testable research plans without treating…

K-Dense-AI/scientific-agent-skills · 58 tokens

neuropixels-analysis

Analyze Neuropixels extracellular recordings end-to-end with SpikeInterface. Covers loading SpikeGLX/Open Ephys/NWB data, preprocessing, drift/motion correction, Kilosort4 (and CPU) spike sorting, quality metrics, and unit curation (threshold-based, model-based UnitRefine, and AI-assisted visual review). Use when…

K-Dense-AI/scientific-agent-skills · 98 tokens

onekgpd

Query the 1000 Genomes Project dataset (3,202 whole-genome-sequenced individuals, GRCh38) at the level of individual participants. Use when a question is about individuals or variants in the 1000 Genomes Project cohort: which individuals carry variants matching specific criteria in a gene or region, which individuals…

K-Dense-AI/scientific-agent-skills · 143 tokens