bioinformatics

bioinformatics is a skill for Claude Code, Codex from AndyZhuang/Opentest. It costs 0 tokens per session (518 once invoked), scanned A, a copy of bioinformatics, MIT.

A guide to computational analysis of biological and genomic data. It covers workflows such as RNA sequencing, single-cell sequencing, and genetic-association studies.

In plain words
What is it for?
Use it to plan or carry out workflows including sequencing quality control, alignment, gene-count analysis, cell clustering, cell-type labeling, pathway analysis, and genome-wide association studies.
Why use it?
It brings the usual analysis stages together, helping you choose steps for quality checks, measurement, comparison, visualization, and biological interpretation.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan or carry out workflows including sequencing quality control, alignment, gene-count analysis, cell clustering, cell-type labeling, pathway analysis, and genome-wide association studies.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/andyzhuang/opentest/bioinformatics
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AndyZhuang/Opentest --skill bioinformatics
Clone the repo
git clone --depth 1 https://github.com/AndyZhuang/Opentest

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bioinformatics

README.md
[![agentmods](https://agentmods.dev/badge/skills/andyzhuang/opentest/bioinformatics/github.svg)](https://agentmods.dev/skills/andyzhuang/opentest/bioinformatics)
Your own site
<a href="https://agentmods.dev/skills/andyzhuang/opentest/bioinformatics"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/bioinformatics/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bioinformatics

Your own site · 80×15
<a href="https://agentmods.dev/skills/andyzhuang/opentest/bioinformatics"><img src="https://agentmods.dev/badge/skills/andyzhuang/opentest/bioinformatics.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 0 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 518 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 100% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00000 $0.00518
Opus 5 $0.00000 $0.00259
Sonnet 5 $0.00000 $0.00104
Haiku 4.5 $0.00000 $0.00052

Measured 9d ago against content hash f60535f6e2eb, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

bioinformatics scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

100% identical to bioinformatics — 0 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/labclaw/bio/bioinformatics/SKILL.md · 51 lines

What it actually says

Bioinformatics Analysis

Overview

Computational biology and genomics analysis pipelines. GENERAL: not locked to any specific tool — use Scanpy, Seurat, DESeq2, or any appropriate package.

Common Workflows

RNA-seq Analysis

  1. Quality control (FastQC, MultiQC)
  2. Alignment (STAR, HISAT2) or pseudo-alignment (Salmon, kallisto)
  3. Quantification (featureCounts, Salmon quant)
  4. Normalization (DESeq2 vst/rlog, edgeR TMM)
  5. Differential expression (DESeq2, edgeR, limma-voom)
  6. Visualization (volcano plot, MA plot, heatmap)
  7. Pathway analysis (clusterProfiler GO/KEGG, GSEA)

scRNA-seq Analysis (Scanpy / Seurat)

  1. Quality control (filter cells: mito%, gene count, UMI count)
  2. Normalization (library size, log1p)
  3. Feature selection (highly variable genes)
  4. Dimensionality reduction (PCA → UMAP/tSNE)
  5. Clustering (Leiden, Louvain)
  6. Marker identification (Wilcoxon, t-test)
  7. Cell type annotation (manual markers or automated)
  8. Trajectory analysis (PAGA, diffusion pseudotime)

GWAS / Genomics

  1. Quality control (MAF, HWE, call rate, relatedness)
  2. Association testing (PLINK, REGENIE)
  3. Multiple testing correction (Bonferroni, FDR)
  4. Manhattan plot, Q-Q plot
  5. Fine-mapping, colocalization

Key Databases

  • GEO (Gene Expression Omnibus): public expression datasets
  • TCGA (The Cancer Genome Atlas): cancer genomics
  • GTEx (Genotype-Tissue Expression): tissue-specific expression
  • ClinVar: clinical variant interpretations
  • UniProt: protein sequences and annotations
  • Ensembl: genome annotation

File Formats

Format Content Tools
FASTQ Raw sequencing reads FastQC, Trimmomatic
BAM/SAM Aligned reads samtools, IGV
VCF Variant calls bcftools, GATK
h5ad AnnData (scRNA-seq) Scanpy
RDS R object Seurat, DESeq2
BED Genomic regions bedtools
Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 51 lines · 0 tokens per session scan A f60535f6e2eb

Subscribe to this mod's changes

bioinformatics is a skill published in the GitHub repository AndyZhuang/Opentest (22 stars, last pushed 6mo ago), licensed MIT. It costs nothing until one of its globs matches a file; then it loads 518 tokens. A static security scan graded it A with 0 findings. It is 100% identical to bioinformatics, differing in 0 lines, and is treated as a copy.

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