AndyZhuang/Opentest

Claw-like Agent for bioinformatics

22Stars on the repository
200Mods indexed here, across every type
6mo agoLast push, which is what freshness is scored on
MITLicence, which decides whether bodies are shown

AndyZhuang/Opentest

Skill Claude CodeCodex

Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases. Maps protein identifiers, retrieves interaction networks with confidence scores, performs functional enrichment analysis (GO/KEGG/Reactome), and optionally includes structural data. No API key required for core functionality…

not rated 22 6mo ago A 82 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles. Creates detailed structure reports with experimental metadata, ligand information, and download links. Use when users need protein structures, 3D models…

not rated 22 6mo ago A 94 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Analyze mass spectrometry proteomics data including protein quantification, differential expression, post-translational modifications (PTMs), and protein-protein interactions. Processes MaxQuant, Spectronaut, DIA-NN, and other MS platform outputs. Performs normalization, statistical analysis, pathway enrichment, and…

not rated 22 6mo ago A 110 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Production-ready RNA-seq differential expression analysis using PyDESeq2. Performs DESeq2 normalization, dispersion estimation, Wald testing, LFC shrinkage, and result filtering. Handles multi-factor designs, multiple contrasts, batch effects, and integrates with gene enrichment (gseapy) and ToolUniverse annotation…

not rated 22 6mo ago A 124 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Retrieves biological sequences (DNA, RNA, protein) from NCBI and ENA with gene disambiguation, accession type handling, and comprehensive sequence profiles. Creates detailed reports with sequence metadata, cross-database references, and download options. Use when users need nucleotide sequences, protein sequences…

not rated 22 6mo ago A 84 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering, differential expression (Wilcoxon, t-test, DESeq2), cell type annotation, per-cell-type statistical analysis, gene-expression correlation, batch…

not rated 22 6mo ago A 230 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Computational analysis framework for spatial multi-omics data integration. Given spatially variable genes (SVGs), spatial domain annotations, tissue type, and disease context from spatial transcriptomics/proteomics experiments (10x Visium, MERFISH, DBiTplus, SLIDE-seq, etc.), performs comprehensive biological…

not rated 22 6mo ago A 178 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Analyze spatial transcriptomics data to map gene expression in tissue architecture. Supports 10x Visium, MERFISH, seqFISH, Slide-seq, and imaging-based platforms. Performs spatial clustering, domain identification, cell-cell proximity analysis, spatial gene expression patterns, tissue architecture mapping, and…

not rated 22 6mo ago A 122 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Comprehensive structural variant (SV) analysis skill for clinical genomics. Classifies SVs (deletions, duplications, inversions, translocations), assesses pathogenicity using ACMG-adapted criteria, evaluates gene disruption and dosage sensitivity, and provides clinical interpretation with evidence grading. Use when…

not rated 22 6mo ago A 94 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Comprehensive systems biology and pathway analysis using multiple pathway databases (Reactome, KEGG, WikiPathways, Pathway Commons, BioModels). Performs pathway enrichment, protein-pathway mapping, keyword searches, and systems-level analysis. Use when analyzing gene sets, exploring biological pathways, or…

not rated 22 6mo ago A 70 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions. Parses VCF files (streaming, large files), classifies mutation types (missense, nonsense, synonymous, frameshift, splice, intronic, intergenic) and structural variants…

not rated 22 6mo ago A 238 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Systematic clinical variant interpretation from raw variant calls to ACMG-classified recommendations with structural impact analysis. Aggregates evidence from ClinVar, gnomAD, CIViC, UniProt, and PDB across ACMG criteria. Produces pathogenicity scores (0-100), clinical recommendations, and treatment implications. Use…

not rated 22 6mo ago A 103 tokens original MIT

umap-learn

85

AndyZhuang/Opentest

Skill Claude CodeCodex

UMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.

not rated 22 6mo ago A 43 tokens copy · 91% MIT

uniprot-database

86

AndyZhuang/Opentest

Skill Claude CodeCodex

Direct REST API access to UniProt. Protein searches, FASTA retrieval, ID mapping, Swiss-Prot/TrEMBL. For Python workflows with multiple databases, prefer bioservices (unified interface to 40+ services). Use this for direct HTTP/REST work or UniProt-specific control.

not rated 22 6mo ago A 66 tokens copy · 89% MIT

aeon

87

AndyZhuang/Opentest

Skill Claude CodeCodex

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard…

not rated 22 6mo ago A 74 tokens copy · 100% MIT

article-writing

88

AndyZhuang/Opentest

Skill Claude CodeCodex

Write articles, guides, blog posts, tutorials, newsletter issues, and other long-form content in a distinctive voice derived from supplied examples or brand guidance. Use when the user wants polished written content longer than a paragraph, especially when voice consistency, structure, and credibility matter.

not rated 22 6mo ago A 57 tokens copy · 100% MIT

dask

89

AndyZhuang/Opentest

Skill Claude CodeCodex

Distributed computing for larger-than-RAM pandas/NumPy workflows. Use when you need to scale existing pandas/NumPy code beyond memory or across clusters. Best for parallel file processing, distributed ML, integration with existing pandas code. For out-of-core analytics on single machine use vaex; for in-memory speed…

not rated 22 6mo ago A 69 tokens copy · 83% MIT

AndyZhuang/Opentest

Skill Claude CodeCodex needs its repo

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with…

not rated 22 6mo ago A 89 tokens copy · 88% MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Exports any structured experimental data (JSON, tables, time series) to well-formatted Excel (.xlsx) files. Auto-names sheets (Raw Data, Growth Curves, Cell Counts, etc.), adds unit headers and annotation rows, applies consistent styling, and produces lab-ready spreadsheets for sharing, archival, or downstream…

not rated 22 6mo ago A 79 tokens original MIT

fair-data

92

AndyZhuang/Opentest

Skill Claude CodeCodex

Guidelines for making scientific data FAIR: Findable, Accessible, Interoperable, and Reusable.

not rated 22 6mo ago A 0 tokens copy · 100% MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Generates natural language scene descriptions from 3D Gaussian Splatting reconstructions built from lab photos or short video clips. Outputs structured text with instrument placement, sample positions, spatial layout keywords, and relational predicates — optimized for VLM or spatial intelligence model consumption in…

not rated 22 6mo ago A 72 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Domain-specialized chart generator for cell biology video analysis outputs. Consumes structured JSON from analyzelabvideocellbehavior or compatible sources and produces publication-ready figures — growth curves, cell trajectory maps, phenotype distribution charts, MSD plots, wound-closure timeseries, dose-response…

not rated 22 6mo ago A 94 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Assembles experimental data, figures, methods, and results into a journal-style double-column PDF report. Uses reportlab or PyMuPDF for programmatic generation with title page, embedded figures/tables, section headings, body text flow, and reference placeholders — suitable for internal lab reports, preprint drafts, or…

not rated 22 6mo ago A 74 tokens original MIT

AndyZhuang/Opentest

Skill Claude CodeCodex

Automated SCI-standard Methods section generator from experiment execution records. Parses LabOS skill call chains, structured JSON logs (extractexperimentdatafromvideo, analyzelabvideocellbehavior), protocol text, and ELN entries to produce flowing, past-tense, passive-voice Methods prose with full reagent citations…

not rated 22 6mo ago A 102 tokens original MIT

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